Nucleotide triplets

Chapter 17 - From gene to protein. This chapter presents the following content: The study of metabolic defects provided evidence that genes specify proteins, transcription and translation are the two main processing linking gene to protein, in the genetic code, nucleotide triplets specify amino acids, in the genetic code, nucleotide triplets specify amino acids.

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Deep-sequencing allows for an in-depth characterization of sequence variation in complex populations. However, technology associated errors may impede a powerful assessment of low-frequency mutations. Fortunately, base calls are complemented with quality scores which are derived from a quadruplet of intensities, one channel for each nucleotide type for Illumina sequencing.

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Answers to Review Questions Chapter 1 1.1 Nucleotide insertion. This is a frameshift mutation. Following this mutation, all but the first triplet encode different amino acids. The functionality is changed and therefore mutation is unlikely to be neutral.

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