Obese

Today, the global challenge of malnutrition encompasses both undernutrition and overweight, particularly prevalent in low and middle-income nations. Excessive body fat accumulation poses health risks for overweight and obese individuals. Objectives: To assess nutritional status and identify related factors among Can Tho University of Medicine and Pharmacy (CTUMP) medical students.

7p vinara 11-01-2025 0 0   Download

Obesity is well known that in various human pathological states such as: essential hypertension, coronary heart disease, type 2 diabetes mellitus,... Insulin resistance plays an important role in pathological state of diabetes. Recently, Katz et al provided QUICKI index (Quantitative insulin sensitivity check index) for insulin resistance condition evaluation. We carried out this study to determine the prevalence of insulin resistance by the QUICKI index and to evaluate the correlation between QUICKI index and the fasting glucose, insulin concentration.

4p viuchiha 06-01-2025 0 0   Download

Pancreatic lipase is one of the safest targets of anti-obesity drugs. To date, orlistat is the only pancreatic lipase inhibitor approved for the long-term treatment of obesity. Therefore, there is an elevated need to find new drugs for this disease.

6p viharuno 03-01-2025 1 1   Download

Skeletal muscle-related studies have recently been applied in the combat of obesity and metabolic disorders. Culture skeletal muscle cells in in vitro plays an important role in being a promising model for those researches. In the present study, the C2C12 skeletal muscle cells were grown and differentiated in in vitro.

7p vibenya 31-12-2024 2 1   Download

Nội dung của bài giảng bao gồm các kiến thức như: tăng huyết áp khiến bệnh tim mạch đến sớm; gánh nặng tăng huyết áp tại Việt Nam; tăng huyết áp phi mã trên toàn quốc năm 2015; xu thế tăng huyết áp và cân nặng trên thế giới; xu thế huyết áp và béo phì tại Việt Nam…

26p angicungduoc 13-10-2019 38 4   Download

The aim of this study was to investigate the potential impact of obesity on patients’ clinical outcome and response to the usual post orthopaedic surgery thromboprophylaxis enoxaparin or aspirin. Additionally, the participants perceived barrier(s) to adherence to the prescribed prophylaxis were explored.

224p runthenight04 02-02-2023 3 1   Download

Obesity is a central feature of the metabolic syndrome and is associated with increased risk for insulin resistance and type II diabetes. Here, we investigated the contribution of human apoliprotein E3 and mouse apoli-protein E to the development of diet-induced obesity in response to western-type diet. Our data show that apolipoprotein E contributes to the development of obesity and other related metabolic disorders, and that human apolipoprotein E3 is more potent than mouse apolipoprotein E in promoting obesity in response to western-type diet. ...

14p research12 29-04-2013 48 3   Download

Mitochondrial uncoupling protein 1 (UCP1) is a speci®c marker of multilocular brown adipocytes. Ectopic UCP1 in white fat of aP2-Ucp1micemitigates development of obesity byboth, increasing energy expenditure anddecreasingin situ lipogenesis. In order to further analyse consequences of respiratory uncoupling inwhite fat, the e€ects of the ectopic UCP1 on the morphology of adipocytes and biogenesis of mitochondria in these cells were studied.

10p research12 29-04-2013 42 4   Download

Inhibition of the mitochondrial adenine nucleotide translocator (ANT) by long-chain acyl-CoA esters has been proposed to contribute to cellular dys-function in obesity and type 2 diabetes by increasing formation of reactive oxygen species and adenosine via effects on the coenzyme Q redox state, mitochondrial membrane potential (Dw) and cytosolic ATP concentrations.

15p inspiron33 23-03-2013 55 4   Download

Plasma concentrations of free fatty acids are increased in metabolic syn-drome, and the increased fatty acids may cause cellular damage via the induction of oxidative stress. The present study was designed to determine whether the increase in fatty acids can modify the free sulfhydryl group in position 34 of albumin (Cys34) and enhance the redox-cycling activity of the copper–albumin complex in high-fat diet-induced obese mice.

9p galaxyss3 21-03-2013 41 3   Download

Obesity is a known risk factor for induction of myocardial infarction, but, paradoxically, may also confer a protective effect against subsequent remodeling leading to heart failure. In this study, we investigated the effect of leptin, the product of the obese (ob) gene, on cardiomyocyte apoptosis, a well-characterized component of cardiac remodeling after myocardial infarction.

9p galaxyss3 07-03-2013 53 2   Download

Có một số cách như tắt đèn khi đi ngủ, xem ít TV, ngủ trong phòng lạnh, uống vitamin… có thể giúp bạn giảm cân. 1. Uống vitamin Trong nghiên cứu đăng trên chuyên san International Journal of Obesity, 96 phụ nữ béo phì được chia thành 2 nhóm, trong đó 1 nhóm được yêu cầu uống vitamin tổng hợp và calcium trong 26 tuần, nhóm còn lại dùng giả dược.

9p tethys75 27-02-2013 77 7   Download

Circulating tumour necrosis factor-a(TNFa) levels, which are elevated in obesity-associated insulin resistance and diabetes, inhibit insulin signalling at several points in the signalling cascade. The liver is critical in maintaining cir-culating glucose levels and, in a preliminary investigation using the human hepatoma (HepG2) cell line in this study, we demonstrated the role of TNFa in the regulation of this phenomenon and determined the underlying molecular mechanisms.

13p vinaphone15 25-02-2013 43 2   Download

Sterol regulatory element-binding proteins 1 and 2 (SREBP-1 and SREBP-2) are important regulators of genes involved in cholesterol and fatty acid metabolism, but have also been implicated in the regulation of the cell cycle and have been associated with the pathogenesis of type 2 diabetes, atherosclerosis and obesity, among others.

13p viettel02 22-02-2013 37 3   Download

Obesity is associated with a high prevalence of erectile dysfunction; how-ever, the pathophysiological link between obesity and erectile dysfunction remains poorly understood. In this minireview, we have attempted to eval-uate the existing literature pertaining to obesity and erectile dysfunction to determine whether a common pathophysiological link exists.

13p viettel02 20-02-2013 38 3   Download

Adipose tissue is an endocrine organ made up of adipocytes, various stro-mal cells, resident and infiltrating immune cells, and an extensive endo-thelial network. Adipose secretory products, collectively referred to as adipokines, have been identified as contributors to the negative conse-quences of adipose tissue expansion that include cardiovascular disease, diabetes and cancer.

9p viettel02 20-02-2013 43 5   Download

There is a tightly regulated interaction, which is well-conserved in evolution, between the metabolic and immune systems that is deranged in states of over- or under-nutrition. Obesity, an energy-rich condition, is characterized by the activation of an inflammatory process in metaboli-cally active sites such as adipose tissue, liver and immune cells.

8p viettel02 20-02-2013 30 3   Download

Obesity and its associated disorders, including diabetes and cardiovascular disease, have now reached epidemic proportions in the Western world, resulting in dramatic increases in healthcare costs. Understanding the pro-cesses and metabolic perturbations that contribute to the expansion of adi-pose depots accompanying obesity is central to the development of appropriate therapeutic strategies.

9p viettel02 20-02-2013 65 4   Download

Apolipoprotein E is a polymorphic glycoprotein in humans with a molecu-lar mass of 34.5 kDa. It is a component of chylomicron remnants, very low density lipoprotein, low density lipoprotein and high density lipopro-tein, and is primarily responsible for maintaining plasma lipid homeostasis. In addition to these well-documented functions, recent studies in experi-mental mouse models, as well as population studies, show that apolipo-protein E also plays an important role in the development of obesity and insulin resistance. ...

9p viettel02 20-02-2013 49 2   Download

Obesity is a low-grade chronic inflammatory disease associated with an increased number of macrophages (adipose tissue macrophages) in adipose tissue. Within the adipose tissue, adipose tissue macrophages are the major source of visfatin⁄pre-B-cell colony-enhancing factor⁄nicotinamide phos-phoribosyl transferase.

13p viettel02 19-02-2013 39 3   Download