Ornithine decarboxylase

Leucine decarboxylase (LDC) is a recently proposed enzyme with no official enzyme commission number yet. It is encoded by the Mus musculus gene Gm853 which is expressed at kidneys, generating isopentylamine, an alkylmonoamine that has not been described to be formed by any metazoan enzyme yet. Although the relevance of LDC in mammalian physiology has not been fully determined, isopentylamine is a potential modulator which may have effects on insulin secretion and healthy gut microbiota formation.

16p tudichquannguyet 29-11-2021 4 1   Download

The aim of the study was to speciate the CoNS isolates from various clinical samples and to study their antibiotic susceptibility pattern. Over a period of 18 months from December 2013 to May 2015, 142 Coagulase negative staphylococcal isolates grown in pure culture from various clinical samples were isolated and identified by standard procedure. Speciation of CoNS was done using novobiocin resistance test, urease activity, ornithine decarboxylase, pyrrolidonyl arylamidase and aerobic acid production from mannose.

9p trinhthamhodang7 31-08-2020 11 1   Download

With the increasing interest in metabolic engineering of plants using genetic manipulation and gene editing technologies to enhance growth, nutritional value and environmental adaptation, a major concern is the potential of undesirable broad and distant effects of manipulating the target gene or metabolic step in the resulting plant.

15p vihashirama2711 21-05-2020 7 1   Download

Roscovitine and purvalanol are specific cyclin-dependent kinase (CDK) inhibitors, which induce apoptosis by triggering cell cycle arrest in various cancer cells such as colon, prostate, and breast cancer cells. Although the apoptotic action of roscovitine was clarified at the molecular level, the exact mechanism of purvalanol-induced apoptosis is still under investigation.

13p vikimsa 22-02-2019 16 1   Download

Sáu chủng vi khuẩn phân lập từ lươn đồng (Monopterus albus) bệnh xuất huyết được định danh là Aeromonas hydrophila. Các chủng vi khuẩn mọc trên môi trường tryptone soya agar sau 24 giờ ở 28oC tạo khuẩn lạc tròn, lồi, màu kem, kích thước từ 2-3 mm và gây tan huyết. Chúng là vi khuẩn Gram âm, hình que ngắn, di động, oxidase và catalase dương tính, có khả năng lên men hiếu khí và kị khí. Tất cả đều cho phản ứng arginin dihydrolase và lysine decarboxylase dương tính nhưng ornithine decarboxylase âm tính. Chúng không sinh ureaza nhưng sinh gelatinaza và indol, sử...

10p sunshine_7 19-07-2013 141 20   Download

Antizyme is a polyamine-induced cellular protein that binds to ornithine decarboxylase (ODC), and targets it to rapid ubiquitin-independent degradation by the 26S proteasome. However, the metabolic fate of antizyme is not clear. We have tested the stability of antizyme in mammalian cells. In contrast with previous studies demonstrating stability in vitro in a reticulocyte lysate-based degradation system, in cells antizyme is rapidly degraded and this degradation is inhibited by specific proteasome inhibitors. ...

7p research12 01-06-2013 37 2   Download