Ovarian cancer stem cells
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Immune checkpoint inhibitors, including PD-L1 (programmed death ligand-1) inhibitors have well documented anticancer therapeutic effects in most types of cancers but its use in the treatment of ovarian cancer is not yet proven. The aim of our study is to explore the predictive biomarkers in ovarian cancer and its association with the outcomes.
16p vileonardodavinci 23-12-2023 4 2 Download
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The aim of this work was to screen and validate biomarkers of ovarian cancer-initiating cells to detect the mechanisms of recurrence of epithelial ovarian cancer (EOC). Methods: Stably labelled the amino acid in side population (SP) cells of epithelial ovarian cancer which were rich in cancer-initiating cells and non-SP cells with isotope in culture and differentially expressed cellular membrane proteins in SP cells were identified through proteomics technology.
15p vialfrednobel 23-12-2023 5 3 Download
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Ovarian cancer is the most lethal gynecologic disease and is one of the most commonly diagnosed cancers among women worldwide. The phosphatidylinositol 3-kinase (PI3K) family plays an important regulatory role in various cancer signalling pathways, including those involved in ovarian cancer development; however, its exact function remains to be fully understood.
13p visusanwojcicki 28-06-2022 12 3 Download
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Ovarian cancer is one of the most common cancers in women. Due to the difficulty in early detection and treatment of ovarian cancer, many research studies and clinical trials have been developed to discover more efficient therapies. Besides Western medicine, traditional medicine has gained increased interest as a research field with potential to lead to the production of marketable therapeutic products. With the diversity of tropical plants in Asia, traditional medicine has been very popular and has served as a traditional therapy for generations.
6p trinhthamhodang9 10-12-2020 21 2 Download
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Current treatment of ovarian cancer patients with chemotherapy leaves behind a residual tumor which results in recurrent ovarian cancer within a short time frame. We have previously demonstrated that a single short-term treatment of ovarian cancer cells with chemotherapy in vitro resulted in a cancer stem cell (CSC)-like enriched residual population which generated significantly greater tumor burden compared to the tumor burden generated by control untreated cells.
22p virose2711 24-09-2020 17 0 Download
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To characterize prognostic and risk factors of central nervous system (CNS) metastases in patients with epithelial ovarian cancer (EOC). Methods: A retrospective analysis of Xijing Hospital electronic medical records was conducted to identify patients with pathologically confirmed EOC and CNS metastases.
12p vilisa271 22-09-2020 9 1 Download
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We previously reported that polyploid giant cancer cells (PGCCs) exhibit cancer stem cell properties and express cell cycle-related proteins. HEY PGCCs induced by cobalt chloride generated daughter cells and the daughter cells had a strong migratory and invasive ability.
9p vilisa271 22-09-2020 9 0 Download
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Aldehyde dehydrogenase 1 (ALDH1) is widely used as a specific cancer stem cell marker in a variety of cancers, and may become a promising target for cancer therapy. However, the role of its expression in tumor cells and the microenvironment in different cancers is still controversial.
10p viamsterdam 18-09-2020 10 1 Download
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As ovarian cancer stem cells (CSCs) are responsible for tumor initiation, invasion, metastasis, and chemo-resistance, new stratagems that selectively target ovarian CSCs are critically significant. Our previous work have demonstrated that ovarian cancer spheroid cells are tumorigenic and chemo-resistant, and have the properties of ovarian CSCs.
15p vimoscow2711 29-08-2020 16 1 Download
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Ovarian cancer is a metastatic disease and one of the leading causes of gynaecology malignancy-related deaths in women. Cancer stem cells (CSCs) are key contributors of cancer metastasis and relapse.
16p vinaypyidaw2711 26-08-2020 5 1 Download
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The existence of cancer stem cells (CSCs) within a tumor bulk has been demonstrated for many solid tumors including epithelial ovarian carcinoma (EOC). CSCs have been associated to tumor invasion, metastasis and development of chemoresistant recurrences.
11p vidhaka2711 31-07-2020 11 1 Download
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The tumour microenvironment conferred by mesenchymal stem cells (MSCs) plays a key role in tumour development and progression. We previously determined that platelet-activating factor receptor (PAFR) was overexpressed in ovarian cancer cells (OCCs) and that PAF can promote ovarian cancer progression via PAF/PAFRmediated inflammatory signalling pathways.
10p vimanila2711 25-06-2020 12 1 Download
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Ovarian cancer is the most common malignant tumor of the female reproductive tract. Chemoresistance is a major challenge for current ovarian cancer therapy. However, the mechanism underlying epithelial ovarian cancer (EOC) chemoresistance is not completely uncovered.
12p vikuala271 13-06-2020 14 1 Download
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Applicants are required to provide scholarships to participants. These scholarships should correspond to at least 15% of the total number of participants and cover at least the participation fees. It is recommended that they also cover expenses for travel and subsistence. This requirement will be carefully verified at final report submission stage. The final report of the activity will include scholarship forms filled in and signed by the scholarship holders, stating the expenses covered by the applicant.
48p thamgiacongdong 02-05-2013 29 3 Download
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3D animation in the other hand can be further classified into 3D CGI and 3D motion capture. These forms of animation give a more realistic view of the character because it gives the object the illusion of movement in a three-dimensional perspective. Unlike 2D animation, 3D CGI and 3D motion capture rely more on computer technology rather than the creativity of the artist in drawing an inanimate object. 3D CGI for instance can be done by using three-dimensional animation software alone.
5p seketnoi 29-04-2013 48 6 Download
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In this study they reported the number of patients who were adherent to the ADA diet recommendations and were able to achieve the recommended intakes of various types of fats. They found that levels of adherence to the recommendations was low with only 26.6% of patients consuming the recommended amount of saturated fatty acids (SFAs), 13.0% consuming the recommended ≥10% of dietary energy from polyunsaturated fats, and 38.5% consuming the recommended ≥60% of dietary energy from carbohydrates and monounsaturated fats. They also estimated that 46.
35p dacotaikhoan 26-04-2013 80 2 Download
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Prior to the Separation on October 27, 2004, we were a business division of Old DreamWorks Studios, the diversified entertainment company formed in October 1994 by Steven Spielberg, Jeffrey Katzenberg and David Geffen. As a division of Old DreamWorks Studios, we conducted our business primarily through Old DreamWorks Studios’ animation division. On October 28, 2004, our Class A common stock began trading on the New York Stock Exchange in connection with our initial public offering.
32p hoangphiyeah1tv 24-04-2013 48 4 Download
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ORRAF was established in 1960 to improve the livelihood of small-scale rubber producers, especially those that are located in Southern Thailand. ORRAF is a government enterprise under the administration of the Ministry of Agriculture and Cooperatives.
65p thieubaotrang 23-04-2013 57 5 Download
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In science contexts, it is a problem that argument for aesthetic qualities of products is unclear since science is traditionally based on clear or explicit statements. Particularly, in integrated design processes with a systematic selection of solutions based on statements about quantity and quality, it is unfortunate that the statements about product aesthetics are unclear [1]. When the aesthetics is made the focus of design, many students have a hard time structuring the process.
13p giamdocamnhac 06-04-2013 65 3 Download
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Although nothing can replace the need for you to acquire firsthand experience, if you begin your telemarketing efforts equipped with the right knowledge and strategies, your chances for success increase exponentially. Sure, telemarketing can be challenging and time-consuming, but, with practice, you’ll learn to enjoy acquiring the skills and experience you need to close sale after sale using the telephone!
50p hongphuocidol 03-04-2013 82 8 Download