Pancreatic neuroendocrine tumors

To present a case of recurrent hypoglycemia following Roux-en-Y gastric bypass (RYGB) surgery whose etiology was determined to be a proinsulin-predominant pancreatic neuroendocrine tumor (a proinsulinoma).

5p caothientrangnguyen 09-05-2020 6 0   Download

Li-Fraumeni syndrome is a cancer predisposition syndrome caused by germline TP53 tumor suppressor gene mutations, with no previous association with pancreatic neuroendocrine tumors (PNETs). Here we present the first case of PNET associated with Li-Fraumeni syndrome.

6p vijakarta2711 09-06-2020 3 0   Download

The American Joint Committee on Cancer (AJCC) and the European Neuroendocrine Tumor Society (ENETS) staging classifications are two broadly used systems for pancreatic neuroendocrine tumors.

8p vijakarta2711 09-06-2020 2 0   Download

Lanreotide depot/autogel antitumor activity in intestinal/pancreatic neuroendocrine tumors (NETs) was demonstrated in the phase-3 CLARINET study (NCT00353496), based on significantly prolonged progressionfree survival (PFS) versus placebo.

9p viputrajaya2711 22-06-2020 1 0   Download

Streptozocin (STZ) based chemotherapy is recommended for patients with metastatic pancreatic neuroendocrine tumors (pNET). Temozolomide as mono- or combination therapy has been suggested to be a promising alternative. However, the treatment is costly and not approved for the treatment of pNETs.

7p vimale2711 25-08-2020 4 0   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Duodenal gastrointestinal stromal tumor resembling a pancreatic neuroendocrine tumor in a patient with neurofibromatosis type I (von Recklinghausen’s disease): a case report

4p toshiba25 09-12-2011 36 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Evolving Diagnostic and Treatment Strategies for Pancreatic Neuroendocrine Tumors...

8p thulanh25 06-12-2011 54 2   Download

Pancreatic neuroendocrine neoplasms (p-NENs) are a group of highly heterogeneous tumors with distinct clinicopathological features and long-term prognosis. In 2017, in order to better stratify patients into prognostic groups and predicting their outcomes, World Health Organization (WHO) officially updated its grading system for p-NENs which distinguished these neoplasms among Grading 1 (G1) pancreatic neuroendocrine tumors (p-NETs), G2 p-NETs, G3 p-NETs and G3 pancreatic neuroendocrine carcinomas (p-NECs).

11p virose2711 25-09-2020 7 0   Download

We assessed the activity and toxicity of the XELBEVOCT regimen in patients with metastatic well-to-moderately differentiated neuroendocrine neoplasms (WMD-NEN). Ancillary studies evaluated hypertension, proteinuria, and vascular endothelial growth factor (VEGF) polymorphisms in predicting progression-free survival (PFS) and the predictive role of serum vitamin D in progression-free survival and proteinuria onset.

10p virose2711 25-09-2020 2 0   Download

Neither randomized clinical trials nor meta- analysis are available and evidence is based on a number of retrospective studies with multivariate for mortality risk factors or data from national cancer registries (Gilliland et al., 1997; Hundahl et al., 1998). Unfortunately, very remarkable differences in patient’s selection, staging systems, and clinical management affect the available studies. In particular, radioiodine treatment is not routinely carried out in a standard manner and outcome results of different studies are thus not comparable (Sciuto et al., 2009).

180p wqwqwqwqwq 20-07-2012 69 5   Download

Harrison's Internal Medicine Chapter 89. Pancreatic Cancer Pancreatic Cancer: Introduction Over 90% of pancreatic cancers are ductal adenocarcinomas of the exocrine pancreas. These tumors occur twice as frequently in the pancreatic head compared to the rest of the organ, and tend to be aggressive, often presenting when locally inoperable or after distal metastases have occurred. Patients with pancreatic cancer have a poor prognosis, with a 5-year survival of only 5%. The discussion of pancreatic cancer here will be limited to ductal adenocarcinomas.

5p konheokonmummim 03-12-2010 75 4   Download

Paraneoplastic neurological syndrome (PNS) is a heterogeneous group of disorders affecting any part of the nervous system, in a patient affected by cancer. PNS is estimated to occur in 0.01 to 8 % of cancer patients, with higher incidence in those with small cell lung cancer, gynecological tumours or hematological disease.

4p vimoscow2711 29-08-2020 1 0   Download

Gangliocytic paraganglioma (GP) is an extremely rare benign tumor that commonly arises from the second part of the duodenum. Since GP exhibit neither prominent mitotic activity nor Ki-67 immunoreactivity, this tumor is often misdiagnosed as neuroendocrine tumor (NET) G1 (carcinoid tumor).

9p vialabama2711 21-09-2020 4 0   Download

This process of cohort succession is thus increasing the average literacy rate of the population 60 and older over time. In addition, Phnom Penh elderly represent a larger share of the SEC sample than of the national population of elderly and, as indicated above, since the literacy level of Phnom Penh elderly is above the national average, this also has the effect of raising the average literacy level compared to nationally representative census results. However when tabulations of SEC are limited to persons 66 and older to correspond to the cohorts who were 60 and older in 1998, the...

78p ut_hai_can 26-12-2012 72 17   Download

Combined methods have led to further refinements with, for example, high visuospatial resolution afforded by MRI combined with metabolic information from the lesion site (measured with 18F-fluorodeoxyglucose positron emission tomography; FDG-PET) to indicate location and malignancy of gliomas, which in turn informs radiosurgical targeting. Kapsalaki et al. (Chapter 7) consider MRS spectroscopic profiles for differentiation among ring enhancing lesions including high grade gliomas, abscesses and post-radiation necrosis.

224p wqwqwqwqwq 21-07-2012 84 10   Download

Herein, we describe a novel method that addresses the above-mentioned problems, namely, a semi-intact cell assay coupled with green fluorescence protein (GFP)-visualization techniques. By using the semi-intact cell system, we can observe the morphological changes that occur in “preexisting” organelles during mitosis more easily, and, at the same time, can investigate the effects of exogenously added antibodies, drugs, and recombinant proteins on the process.

330p yeutinh98 22-09-2012 39 7   Download

When someone arrives at a web site, you have a limited amount of attention available. How much time that equates to is unknown. It depends on the competition, visitor's expectations, and how badly they need what your site offers. And when you only have a limited amount of attention, there is a limit to the number of signals you can convey. So aim to make every signal relevant, significant, and helpful . The more efficiently you can communicate what you have to get across, the more likely you are to keep your visitor's attention, and the greater your success.

6p seketnoi 29-04-2013 80 7   Download

Admission to veterinary programmes around the globe is a highly competitive process, with candidates typically required to attain top grades in science-based subjects to qualify for entry. Owing to the large number of applicants to veterinary schools, interviews often form part of the selection process. Although curricula will vary from provider to provider, veterinary programmes are extremely intensive courses of study and typically include pre- clinical, para-clinical and clinical components.

256p wqwqwqwqwq 23-07-2012 41 5   Download

In much of the developing world, health systems at the local level are fundamentally failing to sustain and improve the lives of women. In many cases women are the last to receive adequate health care and are dying because of it. Women are dying because they do not have access to emergency obstetric care when they require it. Women are at risk because their nation, province or village has not placed sufficient priority on ensuring that they are protected from the threat of contracting HIV/AIDS.

12p connicquy 20-12-2012 39 5   Download

This paper provides an overview of the main program of Bank diagnostic work in the field of private sector financial reporting: the Reports on the Observance of Standards and Codes (ROSC) accounting and auditing assessment. It summarizes some of the main findings of the 38 assessments that have been carried out to date, with specific reference to the challenges to the successful implementation of international accounting and auditing standards.

10p taisaovanchuavo 26-01-2013 55 5   Download