Partial response
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The prognosis of patients with Relapsed/Refractory Osteosarcoma (R/R OS) remains dismal without an agreement on systemic therapy. The use of High-Dose Ifosfamide (14 g/sqm) with an external pump in outpatient setting (14-IFO) in R/R OS patients is limited. This study represents the first retrospective cohort analysis focused on evaluating the activity and toxicity of 14-IFO in this setting.
12p vikoch 27-06-2024 1 1 Download
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The irreversible epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) afatinib and dac‑ omitinib are approved for first-line treatment of EGFR mutation-positive non-small cell lung cancer (NSCLC). We aimed to compare the efficacy and safety of afatinib and dacomitinib in this setting.
11p vikoch 27-06-2024 1 1 Download
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The purpose of this study is to evaluate the effects of university social responsibility (USR) on brand equity in the context of private universities in Ho Chi Minh city, Vietnam. The quantitative data set was collected from 167 students in private higher education institutions located in Ho Chi Minh city. Partial least squares structural equation modeling (PLS-SEM) was used to analyse the measurement model and test proposed hypotheses in this study.
12p leminhvu111 07-06-2024 1 0 Download
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This study employs the Stimulus-Organism-Response theory in consumer behavior research to investigate the decision-making process of consumers regarding Buy Now, Pay Later (BNPL) services. Data from 348 university student questionnaires were analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM). The findings highlight the significantly mediating roles of emotion and cognition in shaping trust during the pre-purchase process, ultimately influencing consumers’ intentions to adopt BNPL services.
12p leminhvu111 07-06-2024 1 0 Download
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The primary objective of this study is to examine the factors that influence the implementation of Industry 4.0 among Malaysian and Nigerian Small and Medium Enterprises. The Questionnaires were distributed to SMEs operators in both countries while analysis was done with 74 and 95 responses from Malaysia and Nigeria respectively using Partial Least Square Structural Equation Modelling (PLS-SEM 3).
11p longtimenosee10 26-04-2024 1 1 Download
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The Computer has occupied a comprehensive coverage, especially in education scopes, including in learning-teaching processes, testing, and evaluating. This research aimed to develop computerized adaptive testing (CAT) to measure physics higher-order thinking skills (HOTS), namely PhysTHOTS-CAT.
11p viarnault 25-04-2024 1 1 Download
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Human resource and Technology are the important assets of the organization. For this reason, the purpose of the present study was to examine the impact of advanced Manufacturing technology, human capital and employee empowerment on supply chain performance, furthermore, the mediating role of organizational innovation is examined as well. The data is collected from the employees of manufacturing firms in Indonesia in the form of questionnaire. The response rate of the current study is 63.4 percent.
8p longtimenosee06 27-03-2024 3 2 Download
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Metagenome sampling bias for geographical location and lifestyle is partially responsible for the incomplete catalog of reference genomes of gut microbial species. Thus, genome assembly from currently underrepresented populations may effectively expand the reference gut microbiome and improve taxonomic and functional profiling.
20p vibransone 28-03-2024 4 2 Download
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The gut microbiome plays an important role in immune modulation. Specifically, presence or absence of certain gut bacterial taxa has been associated with better antitumor immune responses. Furthermore, in trials using fecal microbiota transplantation (FMT) to treat melanoma patients unresponsive to immune checkpoint inhibitors (ICI), complete responses (CR), partial responses (PR), and durable stable disease (SD) have been observed.
11p vileonardodavinci 23-12-2023 7 2 Download
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Stereotactic Body Radiation Therapy (SBRT) has been found beneficial for adrenal gland metastases (AGMs) with a high local control rate and low toxicity. The role of SBRT for AGMs in patients with liver cancer has not been well-discussed before. We, therefore, report our two-institution experience to further elaborate on the feasibility and effectiveness of SBRT in the treatment of AGMs from liver cancer.
9p vischultz 20-10-2023 4 1 Download
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Partial breast irradiation (PBI) is standard of care in low-risk breast cancer patients after breast-conserving surgery (BCS). Pre-operative PBI can result in tumor downstaging and more precise target definition possibly resulting in less treatment-related toxicity. This study aims to assess the pathologic complete response (pCR) rate one year after MR-guided single-dose pre-operative PBI in low-risk breast cancer patients.
12p visharma 20-10-2023 4 2 Download
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The aim of the NeckTAR trial is to assess the ability of circulating DNA (cDNA), both tumoral and viral, at three months post-treatment, to predict residual disease, at the time of the neck dissection, among patients with partial cervical lymph node response on PET-CT, after potentiated radiotherapy.
7p vioracle 29-09-2023 5 3 Download
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In the paper, the forced transverse vibration of fractional viscoelastic Euler-Bernoulli is studied. Based on the fractional relationship of stress and strain, the partial differential equation describing transverse vibration of Euler-Bernoulli viscoelastic beam is considered.
13p vidudley 20-02-2023 6 2 Download
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Part 1 of ebook "Advances in 3D printing and additive manufacturing technologies" provide readers with content about: influence of process parameters on tensile strength of additive manufactured polymer parts using taguchi method; determination and comparison of the anisotropic strengths of fused deposition modeling P400 ABS; estimation of the effect of process parameters on build time and model material volume for FDM process optimization by response surface methodology and grey relational analysis;...
89p damtuyetha 16-02-2023 5 2 Download
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Lecture Introduction to Circuits for ECE - Lesson 36: Transfer function in the s-Domain and Poles and Zeros. The main topics covered in this chapter include: laplace transform properties, laplace transform pairs, step response with initial condition, partial fractions – faster method, laplace transform of components,...
16p linyanjun_2408 23-04-2022 11 1 Download
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Peripheral blood and haematopoiesis in bone marrow and liver tissue were investigated in Bufo bufo during the sexual cycle. A combined touch and imprinting tissue method were applied for the haematopoietic cell isolation. The liver is the primary site of erythropoiesis and partial lymphopoiesis. There was a positive correlation between body mass and liver mass, but it was not significant (P > 0.05). The primary role of yellow bone marrow is the maturation of haematopoietic cells, while red bone marrow is responsible for the production of blood cells.
9p dolomite36 30-12-2021 7 0 Download
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Around 200 different lipopeptides (LPs) have been identified to date, most of which are produced via Bacillus and Pseudomonas species. The clinical nature of the lipopeptide (LP) has led to a big surge in its research. They show antimicrobial and antitumor activities due to which mass-scale production and purification of LPs are beneficial. Response surface methodology (RSM) approach has emerged as an alternative in the field of computational biology for optimizing the reaction parameters using statistical models. In the present study, Pseudomonas sp.
16p langthannam 29-12-2021 10 0 Download
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New superabsorbent hydrogels were synthesized through free radical graft copolymerization of partially neutralized acrylic acid (AA) and 2-acrylamido-2-methylpropanesulfonic acid (AMPS) onto carboxymethyl cellulose (CMC) backbones. The structure and morphology of the synthesized superabsorbent hydrogels were characterized by Fourier transform infrared spectroscopy and scanning electron microscope. The effect of the molar ratio of AMPS to AA, the APS concentration, and the CMC content on swelling ratio was optimized.
11p langthannam 29-12-2021 8 0 Download
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In livestock, residual variance has been studied because of the interest to improve uniformity of production. Several studies have provided evidence that residual variance is partially under genetic control; however, few investigations have elucidated genes that control it. The aim of this study was to identify genomic regions associated with within-family residual variance of yearling weight (YW; N = 423) in Nellore bulls with high density SNP data, using different response variables.
13p vitzuyu2711 29-09-2021 16 1 Download
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Asarum heterotropides Fr. Schmidt var. mandshuricum (Maxim.) Kitag. is an important medicinal and industrial plant, which is used in the treatment of various diseases. High light induces accumulation of major bioactive ingredients A. heterotropides volatile oil and this is ascribed to upregulation of key genes such as cinnamyl alcohol dehydrogenase and cytochrome p450719As.
19p vilichoo2711 25-06-2021 17 1 Download