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Pattern disease
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Bone tumors account for approximately 6% of all cancers in children. Malignant bone tumors, commonly occurring in children and adolescents, are associated with high mortality and morbidity. The overall survival of children with primary malignant bone tumors is affected by the stage of disease, time of diagnosis, and treatment response.
10p
vishanshan
27-06-2024
1
1
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Childhood cancer survivors (CCS) are subject to a substantial burden of treatment-related morbidity. Engaging in health protective behaviors and eliminating risk behaviors are critical to preventing chronic diseases and premature deaths. This study is aimed to provide updated information on currently smoking, physical inactivity, binge drinking patterns and associated factors among CCS using a nationwide dataset.
18p
vikoch
27-06-2024
2
1
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The human personality is inextricably bound up with, among other things, the function of the central nervous system. Diseases and malfunctions of the brain, head injuries and neurosurgical operations can all result in permanently altered behaviour patterns. This interrelation between brain and behaviour is most clearly demonstrated in cases involving functional neurosurgery and severe traumatic lesions.
179p
vimeyers
29-05-2024
4
2
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Ebook "Current topics in innate immunity II" compiles the latest advances in this rapidly evolving field as presented by eminent scientists at the 7th International Aegean Conference on Innate Immunity in Rhodes, Greece. It includes topics related to the biology and function of Toll-like and other pattern-recognition receptors, complement and its crosstalk with other physiological systems, inflammatory mechanisms and diseases, natural killer cells, and the cooperative interplay between innate and adaptive immune cells.
357p
ladongphongthanh1008
22-04-2024
6
3
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Heterotaxy (Htx) syndrome comprises a class of congenital disorders resulting from malformations in left-right body patterning. Approximately 90% of patients with heterotaxy have serious congenital heart diseases; as a result, the survival rate and outcomes of Htx patients are not satisfactory.
13p
vibransone
28-03-2024
3
2
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We investigated the features of the genomic rearrangements in a cohort of 50 male individuals with proteolipid protein 1 (PLP1) copy number gain events who were ascertained with Pelizaeus-Merzbacher disease (PMD; MIM: 312080). We then compared our new data to previous structural variant mutagenesis studies involving the Xq22 region of the human genome.
17p
vibransone
28-03-2024
5
2
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In cancer, normal epigenetic patterns are disturbed and contribute to gene expression changes, disease onset, and progression. The cancer epigenome is composed of the epigenetic patterns present in the tumor-initiating cell at the time of transformation, and the tumor-specific epigenetic alterations that are acquired during tumor initiation and progression.
19p
vibransone
28-03-2024
4
2
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Left-sided lesions (LSLs) account for an important fraction of severe congenital cardiovascular malformations (CVMs). The genetic contributions to LSLs are complex, and the mutations that cause these malformations span several diverse biological signaling pathways: TGFB, NOTCH, SHH, and more.
10p
vioraclene
31-03-2024
8
2
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Patterns in expression data conserved across multiple independent disease studies are likely to represent important molecular events underlying the disease. We present the INSPIRE method to infer modules of co-expressed genes and the dependencies among the modules from multiple expression datasets that may contain different sets of genes.
31p
vioraclene
31-03-2024
4
2
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Epigenetic alterations are associated with normal biological processes such as aging or differentiation. Changes in global epigenetic signatures, together with genetic alterations, are driving events in several diseases including cancer. Comparative studies of cancer and healthy tissues found alterations in patterns of DNA methylation, histone posttranslational modifications, and changes in chromatin accessibility.
12p
vibransone
28-03-2024
7
2
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Metastatic breast cancer is a deadly disease with a low 5-year survival rate. Tracking metastatic spread in living patients is difficult and thus poorly understood. Methods: Via rapid autopsy, we have collected 30 tumor samples over 3 timepoints and across 8 organs from a triple-negative metastatic breast cancer patient.
18p
vibransone
28-03-2024
3
1
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Part 2 book "Mayo clinic neurology board review - Basic sciences and psychiatry for initial certification" includes content: Cellular signaling, cellular processes, cellular injury and death, neuropharmacology, sleep pathophysiology, patterns of inheritance in neurogenetic disease, chromosomal syndromes, electroencephalography, nerve conduction studies and needle electromyography, cerebrospinal fluid, evoked potentials, neuroimaging,... and other contents.
206p
muasambanhan07
20-02-2024
4
0
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Factor XII deficiency can be related to either homozygous or compound heterozygous pathogenic variants in the F12 gene. The disease is commonly known as Hageman trait and is inherited in both autosomal recessive or dominant patterns.
4p
vitiki
30-01-2024
4
2
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Diabetes is one of the most widespread endocrine disease with increasingly prevalence in developing countries. To describe the result of glycemia management in type 2 diabetes patients and kidney disorder treated in Vinh Phuc General Hospital in Vietnam, 2023.
7p
vimichaelfaraday
28-12-2023
8
3
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Women from Asian and western countries have vastly different ages of onset of breast cancer, with the disease tending to occur at an older age in the West. Through an investigation of the patterns of old-onset breast cancer (OBC) in Korean women, we aimed to identify the characteristics of Korean OBC and evaluate whether these patterns are changing in relation to increasing westernization.
15p
vileonardodavinci
23-12-2023
4
3
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Nonalcoholic fatty liver disease affects about 24% of the world’s population and may progress to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma (HCC). While more common in those that are obese, NASH-HCC can develop in lean individuals. The mechanisms by which HCC develops and the role of epigenetic changes in the context of obesity and normal weight are not well understood.
13p
vileonardodavinci
23-12-2023
4
2
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COPD affects the quality of a patient’s life and leads to death. Identifying TCM symptoms and clinical patterns proportions in the community will make diagnosis and treatment more effective. This study wished to survey stable COPD patients to find out the proportions of symptoms and patterns in TCM to create a basis for further practice.
6p
vikissinger
21-12-2023
3
1
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To study the pattern and treatment outcome of rectal cancer (RC) with concurrent locoregional recurrence (LR) and distant metastasis (DM) after total mesorectal excision (TME) and to identify patient-, disease-, and treatment-related factors associated with differences in prognosis after concurrent LR and DM.
9p
vileonardodavinci
23-12-2023
10
3
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Gastroesophageal reflux disease (GERD) is a prevalent condition with growing interest in traditional medicine (TM) treatment. However, there is a dearth of TM epidemiological data on GERD in Vietnam. This study aimed to examine the prevalence of TM patterns and evaluate their association with the severity of GERD to lay the groundwork for clinical practice.
5p
vikissinger
21-12-2023
5
2
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Part 2 book "Fundamentals of small animal surgery" includes content: Surgical knot tying, suture materials and basic suture patterns, basic wound healing and wound closure, surgical hemostasis, surgical tubes and drains, canine ovariohysterectomy, postoperative pain management, patient aftercare and followup.
287p
muasambanhan01
11-12-2023
3
2
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