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Peptidylarginine deiminase
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Peptidylarginine deiminase type 4 (PADI4) has been identified as a susceptibility gene for rheumatoid arthritis (RA) by genome-wide association studies. PADI4 is highly expressed in the bone marrow, macrophages, neutrophils, and monocytes.
15p
vioregon2711
22-02-2021
7
2
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The peptidylarginine deiminases (PADIs) convert positively charged arginine residues to neutrally charged citrulline on protein substrates in a process that is known as citrullination or deimination.
10p
vimariana2711
22-12-2020
13
1
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We have recently reported that the expression of peptidylarginine deiminase 2 (PADI2) is regulated by EGF in mammary cancer cells and appears to play a role in the proliferation of normal mammary epithelium; however, the role of PADI2 in the pathogenesis of human breast cancer has yet to be investigated.
17p
viirene2711
03-10-2020
66
1
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Penetration of the mammary gland basement membrane by cancer cells is a crucial first step in tumor invasion. Using a mouse model of ductal carcinoma in situ, we previously found that inhibition of peptidylarginine deiminase 2 (PAD2, aka PADI2) activity appears to maintain basement membrane integrity in xenograft tumors.
14p
vidhaka2711
31-07-2020
15
2
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The number of reproductive references/phrases for the songs in this sample ranged from 0 to 48, with 160 of these songs, or 92% containing one or more reproductive references. Reproductive phrases that were repeated within a song (such as a chorus) were only counted once. For the 57 Country songs there were a total of 340 reproductive references, for an average of 5.96 different reproductive references per song. For the 59 Pop songs a total of 513 reproductive references were identified, with an average of 8.69 references per song. For the 58 R&B...
22p
ut_hai_can
25-12-2012
29
3
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?
9p
thulanh14
19-10-2011
41
2
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case– control study...
6p
thulanh12
13-10-2011
38
1
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