Perinatal stress
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This paper describes the background, aim, and design of a prospective birth-cohort study in Korea called the COhort for Childhood Origin of Asthma and allergic diseases (COCOA). COCOA objectives are to investigate the individual and interactive effects of genetics, perinatal environment, maternal lifestyle, and psychosocial stress of mother and child on pediatric susceptibility to allergic diseases.
12p vimontana2711 05-04-2021 15 1 Download
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Bereaved parents experience higher rates of depressive and post-traumatic stress symptoms after the stillbirth of a baby than after live-birth. Yet, these effects remain underreported in the literature and, consequently, insufficiently addressed in health provider education and practice.
8p vigeorgia2711 30-11-2020 14 2 Download
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Autism Spectrum Disorders (ASD) are neurodevelopmental disorders characterized by varying deficits in social interactions, communication, and learning, as well as stereotypic behaviors. Despite the significant increase in ASD, there are few if any clues for its pathogenesis, hampering early detection or treatment.
12p virubber2711 21-03-2020 8 2 Download
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Vasopressin is one of the most important physiological stress and shock hormones. Copeptin, a stable vasopressin precursor, is a promising sepsis marker in adults. In contrast, its involvement in neonatal diseases remains unknown.
8p virubber2711 21-03-2020 8 2 Download
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Human Mesenchymal Stem Cells (hMSCs) undergo senescence in lifespan. In most clinical trials, hMSCs experience long-term expansion ex vivo to increase cell number prior to transplantation, which unfortunately leads to cell senescence, hampering post-transplant outcomes.
16p vihasaki2711 12-11-2019 12 1 Download
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In summary, recent evidence shows that the prevalence of mental health problems in the perinatal period in LMICs is higher than in HICs, and is more likely to be persistent. There have been no specific studies about the treatment coverage of these conditions in LMICs, but from what is known about the identification and treatment of mental disorders in general in these countries, it can be reasonably expected that perinatal mental health problems are both under-identified and under-treated.
127p can_thai 12-12-2012 52 4 Download