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Perioperative targeted therapy
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Tissue hypoperfusion occurs frequently during surgery and may contribute to postoperative organ dysfunction. There is a need for perioperative treatment protocols aiming at improving tissue oxygenation (StO2). We hypothesised that intra-operative optimisation of StO2 improves tissue perfusion and thus reduces postoperative complications. Furthermore, we evaluated the feasibility of the optimisation algorithm used.
9p
viisaacnewton
26-04-2022
8
1
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Oliguria is associated with a decreased kidney- and organ perfusion, leading to organ damage and increased mortality. While the effects of correcting oliguria on renal outcome have been investigated frequently, whether urine output is a modifiable risk factor for mortality or simply an epiphenomenon remains unclear.
12p
viottohahn
30-03-2022
13
1
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Goal directed therapy (GDT) is able to improve mortality and reduce complications in selected highrisk patients undergoing major surgery. The aim of this study is to compare two different strategies of perioperative hemodynamic optimization: one based on optimization of preload using dynamic parameters of fluidresponsiveness and the other one based on estimated oxygen extraction rate (O2ER) as target of hemodynamic manipulation.
8p
vizhangzhidong
29-12-2021
9
0
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Although Muscle Invasive Bladder Cancer (MIBC) is increasing in incidence, treatment has largely remained limited to radical cystectomy with or without cisplatin-based neoadjuvant and/or adjuvant chemotherapy.
15p
vialabama2711
21-09-2020
8
0
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part 2 book “gynecologic oncology clinical practice and surgical atlas” has contents: perioperative and critical care, targeted therapy and immunotherapy, integrative oncology, quality of life, and supportive care, surgical instrumentation and sutures, uterine procedures, cervical procedures,… and other contents.
862p
tieu_vu13
06-08-2018
32
1
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