Peripheral blood
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Head and neck squamous cell carcinoma (HNSCC) represents a common and heterogeneous malignancy of the oral cavity, pharynx and larynx. Surgery and radio(chemo)therapy are the standard treatment options and also have great influence on the composition of the tumor microenvironment and immune cell functions.
13p vishanshan 27-06-2024 1 1 Download
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Circulating cell-free DNA (cfDNA, liquid biopsy) is a powerful tool to detect molecular alterations. However, depending on tumor characteristics, biology and anatomic localization, cfDNA detection and analysis may be challenging. Gliomas are enclosed into an anatomic sanctuary, which obstacles the release of cfDNA into the peripheral blood.
10p vishanshan 27-06-2024 1 1 Download
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Investigating novel therapeutic strategies for colorectal cancer (CRC) is imperative. However, there is limited research on the use of drugs to target peripheral blood immune cells in this context. To address this gap, we performed a two-sample Mendelian randomization (MR) analysis to identify potential therapeutic targets for CRC.
14p vikoch 27-06-2024 1 1 Download
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In this study, we attempted to non-invasively diagnose glioma development and the presence of IDH mutations using multivariate analysis of the plasma mid-infrared absorption spectra for a comprehensive and sensitive view of changes in blood components associated with the disease and genetic mutations.
14p vikoch 27-06-2024 1 1 Download
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In the context of breast cancer (BC), the correlation between lymphocytes and clinical outcomes, along with treatment response, has garnered attention. Despite this, few investigations have delved into the interplay among distinct peripheral blood lymphocyte (PBL) types, immune attributes, and their clinical implications within the BC landscape.
10p vikoch 27-06-2024 1 1 Download
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Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery.
607p vimeyers 29-05-2024 2 2 Download
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Ebook "DNA damage detection in situ, ex vivo, and in vivo: Methods and protocols" presents all major assays used in molecular and cell biology for the labeling of DNA damage in situ, ex vivo, and in vivo. It brings together recently introduced techniques, as well as those established earlier, which detect and quantify DNA damage at the scales ranging from subcellular to the level of a whole, living organism.
328p dongmelo 27-05-2024 7 2 Download
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Part 1 book "Fitzgerald's clinical neuroanatomy and neuroscience" includes content: Embryologym, cerebral topography; midbrain, hindbrain, spinal cord; meninges; blood supply of the brain; neurons and neuroglia - overview; electrical events; Transmitters and receptors; peripheral nerves; innervation of muscles and joints; innervation of skin, electrodiagnostic examination, autonomic nervous system and visceral afferents.
181p zizaybay1101 30-04-2024 4 2 Download
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Part 1 book "Human physiology" includes content: Introduction to physiology and homeostasis, cell physiology, the plasma membrane and membrane potential, principles of neural and hormonal communication, the central nervous system, the peripheral nervous system - afferent division; special senses, the peripheral nervous system - efferent division, muscle physiology, cardiac physiology, the blood vessels and blood pressure.
412p zizaybay1101 30-04-2024 3 2 Download
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Part 2 book "Human physiology" includes content: The blood; body defenses; the respiratory system; the urinary system; fluid and acid–base balance; the digestive system; energy balance and temperature regulation; principles of endocrinology - the central endocrine glands; the peripheral endocrine glands; the reproductive system.
543p zizaybay1101 30-04-2024 2 2 Download
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Part 2 book "Pocket companion to Robbins cotran pathologic basis of disease" includes content: Red blood cells andbleeding disorders; the lung; head and neck; the gastrointestinal tract; liver and biliary tract; the pancreas; the kidney; the lower urinary tract and male genital system; the female genital tract; the breast; the endocrine system; the skin; bones, joints, and soft tissue tumors; peripheral nerve and skeletal muscle; the central nervous system; the eye.
432p muasambanhan10 06-04-2024 4 0 Download
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Cancer recurrence after tumor resection in early-stage non-small cell lung cancer (NSCLC) is common, yet difficult to predict. The lung microbiota and systemic immunity may be important modulators of risk for lung cancer recurrence, yet biomarkers from the lung microbiome and peripheral immune environment are understudied. Such markers may hold promise for prediction as well as improved etiologic understanding of lung cancer recurrence.
17p viellison 28-03-2024 2 1 Download
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Ebook "Biology and management of unusual plasma cell dyscrasias" focuses on the non-myeloma plasma cell dyscrasias. A key resource for this group of diseases, the book features the latest in emerging knowledge and therapeutic developments, including novel therapies. Each disease-specific chapter discusses biology, disease course, and appropriate therapeutic interventions, covering plasma cell leukemia, plasmacytoma, POEMS Syndrome and Castleman's Disease, Waldenström macroglobulinemia, immunoglobin deposition disease, and cryoglobulinemic syndromes, among others.
207p cotieubac1004 15-03-2024 0 0 Download
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Systemic and local profiles have each been associated with asthma, but parsing causal relationships between system-wide and airway-specific processes can be challenging. We sought to investigate systemic and airway processes in asthma and their causal relationships.
12p vicwell 29-02-2024 2 2 Download
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Positioning a patient on the catheterization table is important for proper cardiac or respiratory function during peripheral vascular interventions. Fowler’s position, where the patient’s head is a 45° angle, is more effective in reducing venous blood volume returning to the heart from the periphery compared with the supine position.
6p vigojek 02-02-2024 2 1 Download
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Part 1 book "Veterinary anatomy - The regional gross anatomy of domestic animals" includes content: Skeletal system (osteology); articular system (syndesmology arthrology); muscular system (myology); digestive system; respiratory system; urinary system; genital system (reproductive system); endocrine organs, heart and pericardium, major blood vessels, lymphatic system, central nervous system, peripheral nervous system, organs of general and special senses,... and other contents.
405p muasambanhan05 22-01-2024 5 2 Download
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Part 1 book "Essentials of domestic animals embryology" includes content: History of embryology, cellular and molecular mechanisms in embryonic development, comparative reproduction, gametogenesis, fertilization, embryo cleavage and blastulation, gastrulation, body folding and coelom formation, neurulation, comparative placentation, development of the central and peripheral nervous system, eye and ear, development of the blood cells, heart and vascular system.
222p muasambanhan04 11-01-2024 7 1 Download
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Early death remains a major factor in survival in APL. We aimed to analyze the risk factors for differentiation syndrome and early death in acute promyelocytic leukemia (APL). The clinical data of APL patients who were newly diagnosed at Mianyang Central Hospital from January 2013 to January 2022 were retrospectively analyzed.
10p vileonardodavinci 23-12-2023 2 2 Download
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Less than half of unselected metastatic cancer patients benefit from the immune checkpoint inhibitor (ICI) therapy. Systemic cancer-related inflammation may influence the efficacy of ICIs and thus, systemic inflammatory markers could have prognostic and/or predictive potential in ICI therapy.
11p vileonardodavinci 23-12-2023 4 2 Download
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To detect circulating tumor cells (CTCs) in the peripheral blood of patients with tumor, and to analyze the significance of CTC detection in tumor diagnosis and monitoring. In the present study, peripheral blood was collected from 125 patients with tumor, and CTCs were isolated and identified.
10p vileonardodavinci 23-12-2023 3 2 Download