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Plasma mtDNA level
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Mitochondrial DNA (mtDNA) is a critical activator of infammation. Circulating mtDNA released causes lung injury in experimental models. We hypothesized that elevated plasma mtDNA levels are associated with acute lung injury (ALI) in septic patients.
9p
vimichigan2711
26-03-2021
10
2
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The mortality rate due to severe sepsis is approximately 30–60%. Sepsis readily progresses to septic shock and multiple organ dysfunction, representing a significant problem in the pediatric intensive care unit (PICU). The aim of this study was to explore the value of plasma mitochondrial DNA (mtDNA) for early diagnosis and prognosis in children with sepsis.
8p
vidublin2711
13-01-2020
16
1
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