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Potential candidate
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Glioblastoma (GBM) is an aggressive brain tumor that exhibits resistance to current treatment, making the identification of novel therapeutic targets essential. In this context, cellular prion protein (PrPC ) stands out as a potential candidate for new therapies.
17p
vikoch
27-06-2024
0
0
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Infrared cameras are versatile technology studied and utilized in enormous distinct applications ranging from human life-supporting fields such as industrial, building science, and medical to research and development area.
4p
viambani
18-06-2024
4
1
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Pluchea pteropoda, an annual plant in the Asteraceae family, has traditionally been used in Vietnamese folk medicine as an alternative treatment for high fever, indigestion, and painful and swollen wounds. The present study investigates the acute toxicity and antiinflammatory effects of P. pteropoda aerial parts ethanol extract (EtPP) in animal models. EtPP exhibited no toxicity in mice with a single dose of up to 5000 mg/kg.
5p
vicarlos
16-05-2024
0
0
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This plant contains natural compounds such as iridoids, naphthalene glycosides, and especially anthraquinones and anthraquinone glycosides. [9,10] Several compositions of M. longissima stems and roots have been reported to inhibit the in vitro replication of the hepatitis B virus. [11,12] Thus, the search for TNF-α inhibitors from the M. longissima plant and their natural constituents, especially anthraquinone compounds, by molecular docking approaches is necessary for the discovery of potential drug candidates for inflammation-mediated diseases.
7p
dianmotminh02
03-05-2024
4
1
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Shigella is a major diarrheal pathogen for which there is presently no vaccine. Whole genome sequencing provides the ability to predict and derive novel antigens for use as vaccines. Here, we aimed to identify novel immunogenic Shigella antigens that could serve as Shigella vaccine candidates, either alone, or when conjugated to Shigella O-antigen.
13p
vibransone
28-03-2024
3
2
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Ebook "Medicinal chemistry and pharmacological potential of fullerenes and carbon nanotubes" particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances.
411p
manmanthanhla0201
27-02-2024
3
1
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Ebook "Bacteriophage applications - Historical perspective and future potential" explores key applications of phage biotechnology and reviews recent advances in phage display technologies. The applications covered were selected on the basis of their significance and representativeness in the field. The small size and enormous diversity of bacteriophages make them ideal candidates for numerous applications across many industries.
88p
lamquandat
28-12-2023
6
2
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Weizmannia coagulans is a potential bacterial candidate for probiotics because of their advantageous characteristics in endospore formation, antibacterial production, and other beneficial human health effects. In this study, we isolated W. coagulans strains from different sample types collected in Hanoi and examined them for probiotic characteristics.
9p
vimichaelfaraday
28-12-2023
8
4
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In the last few decades, pyrazoline-based substances have emerged as potential antimicrobial and anticancer candidates. In concern with antimicrobial activity, this study aims to build a docking model to predict the structure of potential 2-pyrazoline derivatives. The cytotoxicity of some compounds was also evaluated to get insight into the structure–anticancer activity relationship of the 2- pyrazoline derivatives.
8p
vikissinger
21-12-2023
2
1
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To investigate the potential role of Long Non-coding RNAs (lncRNAs) in the progression of osteosarcoma. Methods: The candidate lncRNAs were screened with RNA-seq and confirmed with quantitative real-time PCR. Using MTS, transwell assay, and fow cytometric analysis, the effects of overexpressed lnc-SELPLG-2:1 on cell functions were determined.
15p
vialfrednobel
23-12-2023
6
3
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Episparis tortuosalis Moore, 1867 is a serious pest of the Chukrasia tabularis A. Juss which is widely planted in plantations in Vietnam. A biocontrol option to manage this pest is a priority for the forest sector. The objective of this study was to evaluate whether there are potential biocontrol candidates within the E. tortuosalis population.
8p
vispacex
16-11-2023
2
2
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Aponermin, a circularly permuted tumor necrosis factor-related apoptosis-inducing ligand, is a potential death receptor 4/5-targeted antitumour candidate. Previous phase 1/2 studies have demonstrated the efcacy of aponermin in patients with relapsed or refractory multiple myeloma (RRMM).
14p
visharma
20-10-2023
6
2
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This paper reports two patients with severe hemorrhagic complications due to aortic disease. Long-term prophylactic treatment is recommended if the underlying aortic disease cannot be surgically managed. Tranexamic acid is a potentially safe option to relieve bleeding tendency.
3p
viintuit
26-09-2023
2
0
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During the recent decade, uncultured bacteria have been special interest as potential candidates for discovering novel antibacterial compounds. Two strains C101 and C102 were negative Gram bacteria, only growing on low nutrient media as R2A/3, NB/3, LB/10 and R4/10 compared to the usual.
8p
vimulcahy
18-09-2023
6
3
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Part 2 book "Antiparasitic and antibacterial drug discovery - From molecular targets to drug candidates" includes content: In search of trypanocidal drugs, trypanosomatid protein kinases as potential drug targets, chemotherapeutic development strategies for schistosomiasis, searching new antiparasitics in virtual space, chemical optimization of anthelmintic compounds – a case study,.... and other contents.
255p
oursky04
14-09-2023
3
3
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Advances in the healthcare sector have driven tremendous possibilities as well as the necessity in developing potential innovation towards smart and wearable sensors. However, the preparation and functionalization of the sensing material remain challenging for real-time application.
8p
viberbers
09-08-2023
4
3
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Lactic acid bacteria have been advocated as probiotics to replace antibiotic growth promoters, improve growth performance, and reduce cost production in swine farming. The aim of this study is to identify and evaluate the probiotic traits of strain LCN13 isolated from traditionally fermented feed for swine.
10p
vicaptainmarvel
21-04-2023
4
2
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Thraustochytrium is a heterotrophic marine microalgae genus belonging to the Labyrinthula class, Thraustochytriaceae (Thraustochytrids) family. Recently, studied results have showed that some species/strains of Thraustochytrium genus are potential candidates to produce biomass rich in lipid containing high polyunsaturated fatty acid (PUFAs), especially docosahexaenoic (DHA C22: 6 ω-3), carotenoid, extracellular polysaccharides (EPSs) and enzymes which play a crucial role in human health.
12p
vicaptainmarvel
21-04-2023
4
2
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It has been shown that hematological traits are strongly associated with the metabolism and the immune system in domestic pig. However, little is known about the genetic architecture of hematological traits.
9p
vinarcissa
21-03-2023
5
1
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This paper is intended to present an overview of recent advances and research progress on WPT systems. Three classes of WPT consisting of short-range, mid-range, and long-range, will be analyzed in detail both in terms of fundamentals and applications.
27p
vidudley
20-02-2023
5
2
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