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Potential indicators
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In this study, we demonstrated that the expression of MUC1 was greater in neoplastic tissues than in non-neoplastic tissues of the cervix, and cervical squamous cell carcinoma patients with high MUC1 expression had significantly worse overall survival than did those with low MUC1 expression, indicating its potential for early diagnosis of cervical squamous cell carcinoma.
14p
vishanshan
27-06-2024
1
1
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RACGAP1 not only indicates poor prognosis and limited immunotherapy benefits but also serves as a potential targeted biomarker influencing tumor stemness. Investigating the key genes and mechanisms that influence stemness in lung adenocarcinoma.
13p
vishanshan
27-06-2024
1
1
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Previous studies have identified substantial regional variations in outpatient antibiotic prescribing in Germany, both in the paediatric and adult population. This indicates inappropriate antibiotic prescribing in some regions, which should be avoided to reduce antimicrobial resistance and potential side effects.
13p
vishanshan
27-06-2024
2
1
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Dental caries is the most prevalent chronic childhood disease with numerous predisposing factors. Salivary properties have been linked to progressive dental caries in previous studies. To assess the salivary characteristics among school-going children aged 12 years from two urban and suburban schools in Can Tho city.
7p
vikoch
27-06-2024
3
1
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Accumulating evidence indicates that the use of antibiotics (ATBs) in cancer patients is potentially correlated with patient prognosis. Interestingly, the use of these agents is not uncommon in colorectal cancer (CRC) patients during surgery; however, their prognostic value in the clinic has never been addressed.
11p
vikoch
27-06-2024
2
1
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Our previous studies have indicated that mRNA and protein levels of PPIH are significantly upregulated in Hepatocellular Carcinoma (LIHC) and could act as predictive biomarkers for patients with LIHC. Nonetheless, the expression and implications of PPIH in the etiology and progression of common solid tumors have yet to be explored, including its potential as a serum tumor marker.
13p
vikoch
27-06-2024
1
1
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Brachytherapy has been indicated as an alternative option for treating cystic craniopharyngiomas (CPs). The potential benefits of brachytherapy for CPs have not yet been clarified. The purpose of this work was to conduct a meta-analysis to analyze the long-term efficacy and adverse reactions profile of brachytherapy for CPs.
13p
vikoch
27-06-2024
3
1
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The book also describes what cerebral monitoring can do and what its limitations are. In addition, proper selection of the available monitoring devices, set-up procedures, the technique of electrode placement, trouble shooting and data interpretation are fully covered. Various typical cases underline how EEG power spectra and evoked potential changes are interpreted, how they are used in the light of other variables being measured how they can serve to get a deeper insight into the underlying clinical situation.
183p
vimeyers
29-05-2024
4
2
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The melting points of the complexes were >350oC, indicating high thermal stability. Cu-Zn-containing complex showed the least binding energy against the three proteins. The bioactivity scores of the complexes were between -0.50 and 0.0. Against A549 Cu-Zn, Co-Zn and Fe-Zn containing complexes showed potential activity. Against MCF-7, Fe-Cu containing complex had IC50 of 53.5 whereas Co-Zn containing complex was active against HepG2. Three complexes were active against S. aureus in the tested range.
18p
dianmotminh02
03-05-2024
2
1
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The purpose of the study is to develop evaluation methodology and evaluate agro-industrial territorial-economic systems that have a significant production potential of agricultural sectors in the regions of the Russian Federation. The author justifies the choice of indicators and evaluation criteria. The study was based on economic and mathematical modeling of empirical spatial data, calculated on the basis of official statistical information within the Russian Federation regions.
11p
longtimenosee10
26-04-2024
2
1
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The article substantiates the idea that increasing social inequality and persistent large-scale poverty in post-Soviet Russia should be considered as one of the main reasons for the low birth rate in the country and a serious challenge to ensuring its demographic security. The authors propose a concept of demographic security and outline its primary indicators and their threshold values—the methodological basis for diagnosing and forecasting demographic processes from the perspective of Russia’s national and economic security.
10p
longtimenosee09
08-04-2024
4
1
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The research carried out a critical analysis of existing labor potential assessment methodologies at the regional level, which allowed taking into account the identified deficiencies offer the author's approach to express diagnostics, which does not require a special wide survey, allows to get objective results and it is the basis for identifying the most important problems and priority ways of solving them. The essence of the approach is to conduct regional clustering procedure on the level of the state of the labor potential on the basis of the author's indicator system.
8p
longtimenosee09
08-04-2024
3
1
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In the context of a need to expand the export potential of greenhouse vegetables of Uzbekistan, the goal of this research was to develop an approach to determining development strategies for greenhouse businesses in Uzbekistan on the international vegetable market. By means of correlation and regression analysis and a method of expert assessment, a system of indicators has been determined that quantitatively and qualitatively defines the competitiveness of Uzbek greenhouse businesses on the international vegetable market.
11p
longtimenosee09
08-04-2024
7
2
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The study aims to investigate potential instabilities in the dike's soil structure. The findings of the research indicate that using the SLOPE/W module of the GEOSTUDIO software with GLEM provides the recommended factor of safety (FOS).
7p
visergey
02-04-2024
4
1
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Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures. Intriguingly, rapidly emerging data indicate that altered genes representing oncogenic drivers can also be found in sporadic non-malignant conditions, some of which have negligible and/or low potential for transformation to cancer.
19p
vibransone
28-03-2024
1
1
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Despite a myriad of attempts in the last three decades to diagnose ovarian cancer (OC) earlier, this clinical aim still remains a significant challenge. Aberrant methylation patterns of linked CpGs analyzed in DNA fragments shed by cancers into the bloodstream (i.e. cell-free DNA) can provide highly specific signals indicating cancer presence.
14p
vioraclene
31-03-2024
3
1
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The purpose of the study is to develop a supply chain strategy for classifying border cities as supporting and indicators for assessing their development level. The main research methods were the analytical, monographic, statistical methods, the score method, as well as the sum of places method (rating method) for conducting an aggregate assessment of the potential of integration cooperation.
12p
longtimenosee06
27-03-2024
6
2
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Ebola virus disease (EVD) is an often-fatal infection where the effectiveness of medical countermeasures is uncertain. During the West African outbreak (2013–2016), several patients were treated with different types of antiviral therapies including monoclonal antibody-based cocktails that had the potential to neutralise Ebola virus (EBOV). However, at the time, the efficacy of these therapies was uncertain.
18p
vibransone
28-03-2024
5
2
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Evolutionary models of breast cancer progression differ on the extent to which metastatic potential is pre-encoded within primary tumors. Although metastatic recurrences often harbor putative driver mutations that are not detected in their antecedent primary tumor using standard sequencing technologies, whether these mutations were acquired before or after dissemination remains unclear.
19p
vicwell
29-02-2024
4
2
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Ebook "Phytochemicals - Biosynthesis, function and application: Volume 44" were selected to showcase exciting examples of current research in plant chemistry, to highlight the diversity in this field spanning analytical chemistry, ethnobotany, biosynthesis, bioactivity, chemical ecology and biotechnology. Overall, these seven Perspectives and Communications give a very good picture of the state of plant (bio) chemistry research in North America, which is also indicative of the state of the field worldwide.
186p
manmanthanhla0201
26-02-2024
1
1
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