Predictive score
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The objective of this study was to externally validate the KELIM (rate of elimination of CA-125) score in patients with high-grade serous ovarian cancer (HGSC) undergoing NACT and explore its relation to the completeness of IDS and survival.
8p vishanshan 27-06-2024 1 1 Download
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The prognostic significance of tumor burden score (TBS) in relation to carcinoembryonic antigen (CEA) has not been investigated among patients undergoing hepatectomy for intrahepatic cholangiocarcinoma (ICC). This study aimed to develop and validate a simplified model, a combination of TBS and CEA (CTC grade), for predicting the long-term outcomes of postoperative ICC patients.
14p vishanshan 27-06-2024 2 1 Download
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Insufficient evidence existed about the prognostic role of the advanced lung cancer inflammation index (ALI) for gastric cancer patients who underwent curative resection. The aim of this study was to identify the predictive ability of ALI for survival after curative gastrectomy.
11p vishanshan 27-06-2024 2 1 Download
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Results regarding whether it is essential to incorporate genetic variants into risk prediction models for esophageal cancer (EC) are inconsistent due to the different genetic backgrounds of the populations studied. We aimed to identify single-nucleotide polymorphisms (SNPs) associated with EC among the Chinese population and to evaluate the performance of genetic and non-genetic factors in a risk model for developing EC.
10p vishanshan 27-06-2024 1 1 Download
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Inflammatory factors have increasingly become a more cost-effective prognostic indicator for gastric cancer (GC). The goal of this study was to develop a prognostic score system for gastric cancer patients based on inflammatory indicators.
13p vikoch 27-06-2024 1 1 Download
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The 17-gene Genomic Prostate Score (GPS) test has been clinically employed to predict adverse prognosis in prostate cancer. In this meta-analysis, we aimed to evaluate the prognostic value of the 17-gene GPS in patients with prostate cancer
9p vikoch 27-06-2024 2 1 Download
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Prognosis prediction for pancreatic cancer has always been difficult in clinical practice because of its high heterogeneity and mortality. The aim of the study was to assess the value of prognostic immune-inflammatorynutritional (PIIN) score on overall survival (OS) in postoperative patients with pancreatic cancer and to develop a nomogram incorporating PIIN score.
10p vikoch 27-06-2024 1 1 Download
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This research aimed to investigate the utility and predictive value of the CRAFITY score in HCC patients receiving combined of TACE plus ICIs and TKIs therapy. We performed a single center retrospective study to broaden the use of the CRAFITY score.
12p vikoch 27-06-2024 2 1 Download
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The melting points of the complexes were >350oC, indicating high thermal stability. Cu-Zn-containing complex showed the least binding energy against the three proteins. The bioactivity scores of the complexes were between -0.50 and 0.0. Against A549 Cu-Zn, Co-Zn and Fe-Zn containing complexes showed potential activity. Against MCF-7, Fe-Cu containing complex had IC50 of 53.5 whereas Co-Zn containing complex was active against HepG2. Three complexes were active against S. aureus in the tested range.
18p dianmotminh02 03-05-2024 2 1 Download
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The purpose of this research was to investigate the relationship between foreign language anxiety, shyness, language learning strategies, speaking scores and academic achievement of university preparatory students learning German. In addition, it was aimed to determine how the independent variables predict the speaking scores and academic achievement.
13p viarnault 25-04-2024 4 1 Download
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Summative assessment of students' writing predicts not only the extent to which the course learning objectives have been achieved but also reveals the relevance of the assessment design with the construct of writing being assessed.
13p viarnault 25-04-2024 1 1 Download
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The main contributions of this research are identifying 4 key categories to predict contractors’ ability to deliver Lean projects, designing an easy to use scoring system for the identified categories and finally using AHP to merge the categories and the scoring system in a flexible well-structured contractor ranking model.
8p longtimenosee10 26-04-2024 2 1 Download
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The paper discusses how the traditional method of association rule mining based on user-defi ned minimum support and confi dence can result in either too many or too few association rules. This could lead to valuable information being missed or redundant rules being generated, which is not practical and can be costly to implement.
7p vijaychest 24-04-2024 3 2 Download
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Several polygenic risk scores (PRS) have been developed for cardiovascular risk prediction, but the additive value of including PRS together with conventional risk factors for risk prediction is questionable. This study assesses the clinical utility of including four PRS generated from 194, 46K, 1.5M, and 6M SNPs, along with conventional risk factors, to predict risk of ischemic heart disease (IHD), myocardial infarction (MI), and first MI event on or before age 50 (early MI).
16p vibransone 28-03-2024 3 2 Download
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Splicing of genomic exons into mRNAs is a critical prerequisite for the accurate synthesis of human proteins. Genetic variants impacting splicing underlie a substantial proportion of genetic disease, but are challenging to identify beyond those occurring at donor and acceptor dinucleotides.
12p vibransone 28-03-2024 3 2 Download
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Accurately quantifying the risk of osteoporotic fracture is important for directing appropriate clinical interventions. While skeletal measures such as heel quantitative speed of sound (SOS) and dual-energy X-ray absorptiometry bone mineral density are able to predict the risk of osteoporotic fracture, the utility of such measurements is subject to the availability of equipment and human resources.
15p vibransone 28-03-2024 4 2 Download
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Acute myocardial infarction (MI) is one of the leading causes of cardiovascular death and can experience many events during illness. The study looked at five major events including death, coronary reintervention, bleeding due to drug use, re-hospitalization, and stroke.
11p vilarry 12-03-2024 6 2 Download
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Early identification of genetic risk factors for complex diseases can enable timely interventions and prevent serious outcomes, including mortality. While the genetics underlying many Mendelian diseases have been elucidated, it is harder to predict risk for complex diseases arising from the combined effects of many genetic variants with smaller individual effects on disease aetiology.
13p vicwell 29-02-2024 5 2 Download
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Although polygenic risk score (PRS) has emerged as a promising tool for predicting cancer risk from genome-wide association studies (GWAS), the individual-level accuracy of lung cancer PRS and the extent to which its impact on subsequent clinical applications remains largely unexplored.
11p vicwell 29-02-2024 4 1 Download
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There is no consensus on the role of serum dehydroepiandrosterone (DHEA) concentrations in the detection of prostate cancer. This study examined the efectiveness of serum DHEA in predicting candidate patients for active surveillance (AS) prior to prostate biopsy.
9p vileonardodavinci 23-12-2023 3 2 Download