Premature atherosclerosis
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Early vascular alteration, atherosclerosis and coronary artery disease have emerged as important cardiovascular complications among beta-thalassemia major (B-TM) patients. The aims of the current study were to assess the prevalence of premature atherosclerosis among our B-TM patients, and to investigate the diagnostic value of serum Osteoprotegerin assay as an early biomarker for atherosclerosis.
8p videshiki2711 19-02-2020 8 0 Download
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The aim of the study was to evaluate serum parameters of lipid metabolism, homocysteine, soluble adhesion molecules and common carotid artery wall thickness in children from families with early symptoms of atherosclerosis.
7p vidr2711 19-02-2020 13 1 Download
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Familial hypercholesterolaemia (FH) is the most common inherited metabolic disease with an autosomal dominant mode of inheritance. It is characterised by raised serum levels of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-c), leading to premature coronary artery disease.
8p vidublin2711 13-01-2020 12 1 Download
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Familial hypercholesterolemia (FH) is an inherited disorder of lipid metabolism. FH is characterized by raised serum LDL - C levels, leading to accelerated atherosclerosis and increased risk of premature coronary heart disease. More than 80% of the time, FH is caused by mutations in the LDL receptor. The LDL receptor consists of 18 exons, and the largest number of LDLR mutations are believed to be in exons 4 and 3. The aim of our study was to examine mutations in exons 3 and 4 of the LDLR gene in Vietnamese patients with FH.
8p quenchua1 04-11-2019 20 1 Download