Premenopausal patients
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Diphereline is a Gonadotropin-Releasing Hormone agonist commonly used in patients with breast cancer. This study aimed to compare the efficacy and safety of one-month and three-month Microrelin injections produced by Homa Pharmed Company with three-month Diphereline injections manufactured by IPSEN, France.
10p vileonardodavinci 23-12-2023 3 2 Download
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Interleukin-10 and tumor necrosis factor α play an important role in breast carcinogenesis. Genes, encoding those two cytokines, contain single nucleotide polymorphisms, which are associated with differential levels of gene transcription.
11p vinarcissa 21-03-2023 1 1 Download
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Young breast cancer (BC) patients less than 45 years old are at higher risk of dying from the disease when compared to their older counterparts. However, specific risk factors leading to this poorer outcome have not been identified.
9p vijennie2711 29-09-2020 15 0 Download
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Toremifene (TOR) is a selective oestrogen receptor modulator (SERM) and has comparable efficacy to that of tamoxifen (TAM) in breast cancer patients. Herein, we compared the safety of TOR to that of TAM in the adjuvant treatment of premenopausal breast cancer.
10p vidhaka2711 31-07-2020 13 1 Download
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Breast cancer (BC) patients with late-stage and/or rapidly growing tumors are prone to develop high serum calcium levels which have been shown to be associated with larger and aggressive breast tumors in post and premenopausal women respectively.
8p vidhaka2711 31-07-2020 14 1 Download
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The numerous side effects of chemotherapy in patients with breast cancer are well known. However, the precise effects of chemotherapy on ovarian function in premenopausal women are poorly investigated. The patients are at risk of developing sexual hormone deficiency and impaired fertility.
9p vimanama2711 30-07-2020 12 1 Download
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Tamoxifen is a frontline therapy for estrogen receptor (ER)-positive breast cancer in premenopausal women. However, many patients develop resistance to tamoxifen, and the mechanism underlying tamoxifen resistance is not well understood.
13p vibaku2711 22-07-2020 11 1 Download
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Several trials evaluated the role of ovarian function suppression for the adjuvant treatment of premenopausal patients with hormone receptor-positive early breast cancer.
11p vimanila2711 25-06-2020 11 1 Download
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In this study, we observe the patterns initial palliative treatment for premenopausal patients with HRpositive/HER2-negative MBC and determine if nonadherence to clinical guidelines are associated with worse clinical outcomes in terms of progression-free survival (PFS) and overall survival (OS) in the South Korean population.
8p viputrajaya2711 22-06-2020 7 1 Download
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Premenopausal women had a higher survival rate than postmenopausal patients in groups treated by endocrine therapy or chemotherapy. Postmenopausal women had lower levels of survival than premenopausal women. This might be attributable to more poor prognostic factors in postmenopausal women. The cancer-specific survival in the present study was comparable to that for patients from other Asian and Western countries.
11p nguyentuananh2502 03-04-2019 23 0 Download
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Treatment algorithm for tomography; chemotherapy. PET, positron squamous cell CUP. tomography; RT, CT, computed radiation; C, emission Treatment of Favorable Subsets of CUP Women with Isolated Axillary Adenopathy Women with isolated axillary adenopathy with adenocarcinoma or carcinoma should be treated for stage II or III breast cancer. These patients should undergo a breast MRI if mammogram and ultrasound are negative. Radiation therapy to the ipsilateral breast is indicated if the breast MRI is positive.
5p thanhongan 07-12-2010 58 3 Download
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Screening In contrast to patients who present with advanced disease, patients with early ovarian cancers (stages I and II) are commonly curable with conventional therapy. Thus, effective screening procedures would improve the cure rate in this disease. Although pelvic examination and CA-125 can occasionally detect early disease, these are relatively insensitive screening procedures. Transvaginal sonography is often used, but significant false-positive results are noted, particularly in premenopausal women.
5p konheokonmummim 03-12-2010 72 4 Download