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Primary hepatic carcinoma
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Combination therapy is the primary treatment for unresectable hepatocellular carcinoma (u-HCC). The hepatic functional reserve is also critical in the treatment of HCC. In this study, u-HCC was treated with combined hepatic arterial infusion chemotherapy (HAIC), tyrosine kinase inhibitors (TKIs), and programmed cell death protein-1 (PD-1) inhibitors to analyze the therapeutic response, progression-free survival (PFS), and safety.
10p
vishanshan
27-06-2024
2
1
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Our primary objective was to assess whether these miRNAs could serve as potential biomarkers for distinguishing hepatocellular carcinoma (HCC), even in its early stages, from other liver diseases, particularly liver cirrhosis (LC).
7p
vilarry
12-03-2024
3
1
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Hepatocellular carcinoma (HCC) is a primary tumor of the liver. The majority of HCCs are associated most frequently with chronic B or C viral hepatitis, alcohol intake or aflatoxin exposure. Cirrhosis is a strong risk factor associated with HCC.
8p
vitiki
30-01-2024
9
2
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Although antiviral treatments have been shown to affect the recurrence and long-term survival of patients with hepatocellular carcinoma (HCC) who have high viral loads, the effect of different responses to antiviral therapy on the clinical outcomes remains unclear.
12p
visharma
20-10-2023
5
2
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Cholangiocarcinoma (CHOL) is the second most common primary hepatic malignant tumor, following hepatocellular carcinoma (HCC). CHOL is highly aggressive and heterogeneous resulting in poor prognosis.
13p
visharma
20-10-2023
7
2
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CXC-chemokine receptor 2 (CXCR2) expression was found to be down-regulated on circulating monocytes of cancer patients. Here, we analyze the percentage of CD14+CXCR2+ monocyte subsets in hepatocellular carcinoma (HCC) patients, and investigate the mechanisms that regulate CXCR2 surface expression on monocytes and its biological function.
9p
vioracle
29-09-2023
3
2
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Hepatocellular carcinoma (HCC), the most common primary liver cancer, prevails mainly in males and has long been attributed to androgens and higher circumstantial levels of interleukin-6 (IL-6) produced by resident hepatic macrophages.
13p
vioracle
29-09-2023
6
3
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Transarterial chemoembolization (TACE) is the standard treatment for intermediate stage hepatocellular carcinoma (HCC) (Barcelona Clinic Liver Cancer [BCLC] B). However, it often leads to a poor prognosis and decreased hepatic function especially in patients with BCLC substage B2.
9p
vikolindagrabar
27-07-2022
3
1
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Microwave ablation (MWA) is widely used to treat unresectable primary and secondary malignancies of the liver, and a limited number of studies indicate that ablation can cause not only necrosis at the in situ site but also an immunoreaction of the whole body.
10p
vimoscow2711
29-08-2020
5
1
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Patients with primary and metastatic liver malignancies represent a highly heterogeneous patient pool characterised by some of the shortest life expectancies amongst oncology patients. Investigation and better understanding of liver malignancies is an emerging field which requires high-quality multidisciplinary research and collaboration.
11p
vinaypyidaw2711
26-08-2020
10
0
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Hepatocellular carcinoma (HCC) is a frequent type of primary liver cancer, and its prevalence is increasing worldwide. Indeed, the underlying molecular mechanism is not well understood. Previous studies have shown evidence that tight junction (TJ) components were correlated with carcinogenesis and tumor development.
10p
vibaku2711
22-07-2020
14
2
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Blood counting and the liver function tests, as the routine examinations, can reflect the immune and nutritional status of the body, our aim is to assess the prognostic significance of serum gamma-glutamyltransferase (GGT) levels and AST/ALT in primary hepatic carcinoma.
9p
vikuala271
13-06-2020
9
0
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Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis and primary hepatocellular carcinoma in most parts of the world. The prevalence of HCV infection worldwide has been estimated to be about 3%. Hence the present study was carried out to detect the prevalence of hepatitis C in patients of chronic liver disease. Eighty patients with clinically suspected Chronic Liver Disease attending the outpatient department or admitted in the K R Hospital attached to Mysore Medical College and Research Institute, Mysore from January 2012 to December 2012, were screened for anti-HCV.
5p
quenchua4
16-04-2020
9
1
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