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Primary immunodeficiency
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Diagnosis of primary immunodeficiencies (PIDs) is complex and cumbersome yet important for the clinical management of the disease. Exome sequencing may provide a genetic diagnosis in a significant number of patients in a single genetic test.
15p
vibransone
28-03-2024
2
2
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Part 1 book "Case studies in veterinary immuneology" includes content: Primary ciliary dyskinesia—canine; leukocyte adhesion deficiency—bovine; cyclic neutropenia—canine; chediak–higashi syndrome—feline; severe combined immunodeficiency—equine; selective iga deficiency—canine; failure of passive transfer—equine; feline leukemia virus—feline; feline immunodeficiency virus—feline; bovine viral diarrhea virus—bovine; marek’s disease—avian; infectious bursal disease—avian,... and other contents.
100p
muasambanhan05
16-01-2024
3
0
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Part 3 book "Veterinary immunology" includes content: Organ graft rejection and pregnancy; cancer immunology and immunotherapy; autoimmunity; organ specific autoimmune diseases; immune mediated inflammatory diseases; primary immunodeficiencies; secondary immunological defects; drugs and other agents that affect the immune system; immunodiagnostic techniques; evolution of the immune system.
625p
muasambanhan03
02-01-2024
3
2
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Part 2 book "Veterinary immunology" includes content: Immunity to bacteria and fungi, immunity to viruses, immunity to parasites, type I hypersensitivity, red cell antigens and type ii hypersensitivity, immune complexes and type III, hypersensitivity, type IV hypersensitivity; organ graft rejection; resistance to tumors; autoimmunity; organ specific autoimmune diseases; systemic immunological diseases; primary immunodeficiencies; secondary immunological defects; drugs and other agents that affect the immune system,...and other contents.
291p
muasambanhan03
02-01-2024
5
2
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This study aimed to understand and compare cancer incidence and risk in three patient groups: recipients of solid organ transplant (SOT) or hematopoietic stem cell transplant (HSCT); diagnosis of primary or secondary immunodeficiency disorder (PID/SID); and recipients of tumor necrosis factor inhibitor (TNF-i) therapy.
9p
vileonardodavinci
23-12-2023
4
2
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Part 2 book "Immunology" includes content: Immunity to protozoa and worms; primary immunodeficiencies; aids, secondary immunodeficiency and immunosuppression; vaccination; immunological tolerance; autoimmunity and autoimmune disease; transplantation and rejection; immunity to cancers; immediate hypersensitivity; hypersensitivity; hypersensitivity; hypersensitivity.
289p
oursky08
04-11-2023
1
1
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Prior reports described cases of lymphoproliferative diseases occurring after methotrexate (MTX) administration, which are called methotrexate-associated lymphoproliferative disorders (MTX-LPDs). It has become clear that these lymphoproliferative diseases also occur following treatment with other immunosuppressive drugs, and they have been termed as other iatrogenic immunodeficiency-associated lymphoproliferative disorders (OIIA-LPDs).
7p
viintuit
26-09-2023
4
0
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Primary colorectal lymphoma is incredibly rare and cases of iatrogenic immunodeficiency associated lymphoproliferative disorder (IILPD) isolated to colorectal area are even more uncommon. Immunodeficiency associated lymphoproliferative disorders can occur in association with primary immune disorders such as inflammatory bowel diseases (IBDs) which are often treated with various immunomodulatory drugs.
4p
viwhitewolf
03-07-2023
6
2
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Wiskott–Aldrich syndrome is a rare X-linked primary immunodeficiency that mostly presents with a classic triad of eczema, macrothrombocytopenia, recurrent infections, and increased risk of autoimmunity/ malignancies.
5p
vigamora
23-05-2023
3
2
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Immune dysregulation-Polyendocrinopathy-Enteropathy-X-linked (IPEX) syndrome is a lifethreatening congenital autoimmune disorder caused by mutations in the forkhead box protein 3 (FOXP3) gene. Typical clinical manifestations of IPEX patients are early onset of intractable diarrhea, type 1 diabetes mellitus, and skin diseases.
8p
vicaptainmarvel
21-04-2023
4
2
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Phosphoinositide 3-kinase (PI3K) signaling pathway is essential for normal physiology and is impaired in diseases such as premalignant hyperproliferative disorders, primary immunodeficiency, metabolic disorders, and cancer. Although the core PI3K pathway components are known today, a long-standing gap in our knowledge of PI3K signaling concerns how distinct PI3K isoforms and their activity patterns contribute to the functional consequences of pathway upregulation.
9p
lyhuyenthu
31-01-2023
3
2
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Skin lesions and dermatoses in cattle are often associated with infections due to bacteria, fungi or environmental risk factors. Dermatoses with genetic etiology have been described in cattle. Among these rare disorders, there are primary congenital dermatoses that are associated with inherited nutritional deficiencies, such as bovine hereditary zinc deficiency or zinc deficiency-like syndrome.
10p
vihagrid
30-01-2023
5
3
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Inborn errors of immunity (IEI) are a group of genetic disorders that impair the immune system, with over 400 genes described so far, and hundreds more to be discovered. To facilitate the search for new genes, we need a way to prioritize among all the genes in the genome those most likely to play an important role in immunity.
8p
vitzuyu2711
29-09-2021
10
1
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GATA-2 transcription factor deficiency has recently been described in patients with a propensity towards myeloid malignancy associated with other highly variable phenotypic features: chronic leukocytopenias (dendritic cell-, monocyto-, granulocyto-, lymphocytopenia), increased susceptibility to infections, lymphatic vasculature abnormalities, and sensorineural deafness.
7p
vimontana2711
05-04-2021
9
2
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Hyperimmunoglobulin E syndrome (HIES) is a rare primary immunodeficiency disorder defined by high serum immunoglobulin E titers that is associated with recurrent respiratory infections, formation of pneumoatoceles, recurrent skin abscesses, and characteristic dental and skeletal abnormalities.
5p
vimontana2711
05-04-2021
8
1
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Common variable immunodeficiency (CVID) is a group of heterogeneous primary immunodeficiencies characterised by a dysregulated and impaired immune response. In addition to an increased susceptibility to infection, it is also associated with noninfectious autoimmune and lymphoproliferative complications.
8p
vimichigan2711
26-03-2021
16
2
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Integrating self-collected, communitybased screening offers a potential primary screening method in areas of limited resources. In this paper, we present a study evaluating knowledge, attitudes, and practices of cervical cancer and Human Papilloma Virus (HPV) in rural Zimbabwe.
10p
vitokyo2711
31-08-2020
22
4
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Human primary myeloma (MM) cells do not survive in culture; current in vitro and in vivo systems for growing these cells are limited to coculture with a specific bone marrow (BM) cell type or growth in an immunodeficient animal model.
14p
vimoscow2711
29-08-2020
7
1
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Human immunodeficiency virus (HIV) is a retro virus known to be the primary aetiological agent of Acquired Immunodeficiency syndrome (AIDS). It is reported that about 39 million people globally are living with HIV. HIV infected patients are frequently present with elevated levels of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST). This has been often attributed to the hepatic effects of Antiretroviral- Protease Inhibitor drugs (PI’s).
7p
nguaconbaynhay6
23-06-2020
8
1
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Enteric microbial agents in HIV differ in several ways between developing and developed world, the awareness of which can often guide appropriate prevention and patient treatment when limitation of resources prevent laboratory diagnosis of exact etiological agent. The primary objective of this study was to define and compare enteric bacterial pathogens in HIV-1 infected with diarrheal symptoms and non-HIV infected controls with diarrheal symptoms at a tertiary care hospital in northern India.
8p
kethamoi5
03-06-2020
6
0
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