![](images/graphics/blank.gif)
Pro-peptide
-
Bài viết Nghiên cứu khoảng tham chiếu dấu ấn chu chuyển xương ở phụ nữ chưa mãn kinh tại Bệnh viện Đại học Y Dược thành phố Hồ Chí Minh trình bày việc xây dựng khoảng tham chiếu dấu ấn tạo xương Osteocalcin (OC), Procollagen type 1 aminoterminal propeptid (P1NP) và dấu ấn hủy xương Beta-CrossLaps (β-CTX) ở phụ nữ chưa mãn kinh tại Bệnh viện Đại học Y Dược thành phố Hồ Chí Minh.
6p
vighostrider
01-06-2023
8
4
Download
-
Plant defensins are small (45–54 amino acids), basic, cysteine-rich proteins that have a major role in innate immunity in plants. Many defensins are potent antifungal molecules and are being evaluated for their potential to create crop plants with sustainable disease resistance.
13p
vijichea2711
28-05-2021
8
1
Download
-
Our classification of bone turnover status is based on internationally recommended biomarkers of both bone formation (N-terminal propeptide of type1 procollagen, P1NP) and bone resorption (beta C-terminal cross-linked telopeptide of type I collagen, bCTX), using the cutoffs proposed as therapeutic targets.
16p
vinasaki2711
12-11-2019
14
1
Download
-
Arecombinant streptococcalC5apeptidasewas expressed in Escherichia coliand its catalytic properties and thermal sta-bility were subjected to examination. It was shown that the NH2 -terminal region ofC5a peptidase (Asn32–Asp79/ Lys90) forms the pro-sequence segment. Upon maturation the propeptide is hydrolyzed either via an autocatalytic intramolecular cleavage or by exogenous protease strepto-pain. At pH 7.4 the enzyme exhibited maximum activity in the narrow range oftemperatures between 40 and 43C....
13p
research12
29-04-2013
41
2
Download
-
The heat- and pressure-induced unfolding of the glycosyl-ated and unglycosylated forms of mature carboxypeptidase Y and the precursor procarboxypeptidase Y were analysed by differential scanning calorimetry and/or by their intrinsic fluorescence in the temperature range of 20–75Corthe pressure range of 0.1–700 MPa. Under all conditions, the precursor form showed a clear two-state transition from a folded to an unfolded state, regardless of the presence of the carbohydrate moiety.
7p
fptmusic
12-04-2013
48
1
Download
-
To study the roles of the catalytic activity, propeptide, and N-glycosylation of the intracellular aspartic proteinase cathepsin E in biosynthesis, process-ing, and intracellular trafficking, we constructed various rat cathepsin E mutants in which active-site Asp residues were changed to Ala or which lacked propeptides and N-glycosylation.
11p
dell39
27-03-2013
48
2
Download
-
Mature lung surfactant protein C (SP-C) corresponds to residues 24–58 of the 21 kDa proSP-C. A late processing intermediate, SP-C i, corresponding to residues 12–58 of proSP-C, lacks the surface activity of SP-C, and the SP-Ci a-helical structure does not unfold in contrast to the metastable nature of the SP-C helix.
10p
inspiron33
26-03-2013
36
4
Download
-
Papain-like cysteine proteases of pathogenic protozoa play important roles in parasite growth, differentiation and host cell invasion. The main cysteine proteases of Trypanosoma cruzi(cruzipain) and of Trypanosoma brucei (brucipain) are validated targets for the development of new chemothera-pies.
11p
galaxyss3
21-03-2013
54
3
Download
-
The proprotein convertase PC1⁄3 preferentially cleaves its substrates in the dense core secretory granules of endocrine and neuroendocrine cells. Sim-ilar to most proteinases synthesized first as zymogens, PC1⁄3 is synthesized as a larger precursor that undergoes proteolytic processing of its signal peptide and propeptide.
10p
galaxyss3
19-03-2013
31
2
Download
-
Vibrio mimicusis a causative agent of human gastroenteritis and food poisoning, and this species produces an enterotoxic hemolysin (V. mimi-cus hemolysin) as a virulence determinant. Vibrio mimicushemolysin is secreted as an 80 kDa precursor, which is later converted to the 66 kDa mature toxin through removal of an N-terminal propeptide via cleavage of the Arg151–Ser152 bond.
10p
vinaphone15
27-02-2013
34
2
Download
-
Matrix metalloprotease-2 is implicated in many biological processes and degrades extracellular and non-extracellular matrix molecules. Matrix metalloprotease-2 maintains a latent state through a cysteine–zinc ion pairing which, when disrupted, results in full enzyme activation. This pairing can be disrupted by a conformational change or cleavage within the propeptide.
14p
viettel02
20-02-2013
43
2
Download
-
Pro-Tk-SP fromThermococcus kodakaraensisconsists of the four domains: N-propeptide, subtilisin (EC 3.4.21.62) domain,b-jelly roll domain and C-propeptide. To analyze the maturation process of this protein, the Pro-Tk-SP derivative with the mutation of the active-site serine residue to Cys (Pro-Tk-S359C), Pro-Tk-S359C derivatives lacking the N-propeptide (ProC-Tk-S359C) and both propeptides (Tk-S359C), and a His-tagged form of the isolated C-propeptide (ProC*) were constructed.
11p
cosis54
05-01-2013
35
3
Download
-
Các túi được cho là di chuyển từ các vùng trong bộ máy Golgi để nghỉ giải lao sâu tế bào chất, nơi mà họ hoàn thành nội dung của họ. Các nghiên cứu trên mô phôi cho thấy rằng N-propeptides vẫn còn gắn liền với sợi 20-30 nm
34p
meomap10
27-12-2011
44
3
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)