Probable protein complexes

Various efforts have been made to elucidate the cooperating proteins involved in maintaining chromatin interactions; however, many are still unknown. Here, we present 3CPET, a tool based on a non-parametric Bayesian approach, to infer the set of the most probable protein complexes involved in maintaining chromatin interactions and the regions that they may control, making it a valuable downstream analysis tool in chromatin conformation studies.

16p viaristotle 29-01-2022 10 0   Download

Streptomyces mobaraensis secretes a Ca 2+ -independent transglutaminase (TGase) that is activated by removing an N-terminal peptide from a precursor protein during sub-merged culture in a complex medium [Pasternack, R., Dorsch, S., Otterbach, J. T., Robenek, I. R., Wolf, S. & Fuchsbauer, H.-L. (1998)Eur. J. Biochem. 257, 570–576]. However, an activating protease could not be identified, probably because of the presence of a 14-kDa protein (P14 ) belonging to theStreptomycessubtilisin inhibitor family. ...

9p tumor12 20-04-2013 26 2   Download

The composition of the chloroplast-localized protease complex, ClpP, from the green alga Chlamydomonas reinhardtiiwas characterized by nondena-turing electrophoresis, immunoblotting and MS. The detected ClpP complex has a native mass of
540 kDa, which is
200 kDa higher than ClpP complexes in higher plant chloroplasts, mitochondria or bacteria. The 540-kDa ClpP complex contains two nuclear-encoded ClpP proteins (ClpP3 and P5) and five ClpR (R1, R2, R3, R4 and R6) proteins, as well two pro-teins, ClpP1Land ClpP1H, both probably derived from the plastid clpP1 gene. ...

14p fptmusic 12-04-2013 42 1   Download

The explosion of new technologies in the post-genomic era is allowing the study of biological systems on a genome-wide scale, at the main functional genomic levels: (epi)-genome, transcriptome, proteome, endo- and exometabolome, and their interactions. At the same time that these techniques are being applied and refined, the complexity of biological systems is being rediscovered (1) with thousands of components (e.g., genes, transcripts, proteins, metabolites) participating in finely tuned metabolic and regulatory networks.

550p bachduong1311 10-12-2012 68 12   Download

This new and updated deals with all aspects of Monte Carlo simulation of complex physical systems encountered in condensed-matter physics and statistical mechanics as well as in related fields, for example polymer science, lattice gauge theory and protein folding. After briefly recalling essential background in statistical mechanics and probability theory, the authors give a succinct overview of simple sampling methods. The next several chapters develop the importance sampling method, both for lattice models and for systems in continuum space....

449p chuyenphimbuon 21-07-2012 87 21   Download