Properties of biomolecules

Ebook "Dynamic studies through control of relaxation in NMR spectroscopy" offers a remarkably cogent view of highly sophisticated NMR methods. Salvi developed these methods in order to characterize the amplitudes and frequency ranges of local motions in biomolecules such as proteins. These local motions play an essential role since they can explain many of the remarkable properties of proteins and enable them to carry out all sorts of vital functions, from enzymatic catalysis to intermolecular recognition and signalling in cells.

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Ebook "Nitric oxide in plants: Metabolism and role in stress physiology" covers the key features of nitric oxide (NO) in plants. Comprising nine chapters, Part I highlights its metabolism and identification in plants. Part II, which consists of eight chapters, focuses on the chemical, physical and biochemical properties of the NO molecule and its derivatives; on its functional role and mode of action; and on its signaling and interaction with phytohormones, mineral nutrients, biomolecules, ions and ion channels in plants under abiotic stresses.

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Optical properties of protein-conjugated metallic nanowires are theoretically investigated based on the Mie theory and the core-shell model. Our numerical calculations show that optical spectra of protein-conjugated nanowires can have more a maximum compared to these nanowires without biomolecules.

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Panax vietnamensis Ha et Grushv. is a species of the genus Panax native to Central Vietnam, containing a family of triterpene saponins named ginsenosides. This group of biomolecules possesses valuable therapeutic properties against cancer, hepatitis, diabetes, inflammation as well as stress and anxiety.

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The mixed ligand coordination compounds containing acesulfamato and N,N-diethylnicotinamide biomolecules of some rare earth metal cations (Eu3+, Tb3+, Ho3+, Er3+ and Yb3+) were synthesized, and their structural properties were investigated. Possible structural formulas have been proposed by determining the chemical composition of molecules (elemental analysis), binding properties (infrared spectroscopy, mass analysis, solid-state UV-vis spectroscopy), thermal degradation properties (TGA / DTA curves).

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Nanoparticles (NPs) are receiving increasing interest in biomedical research owing to their comparable size with biomolecules, novel properties and easy surface engineering for targeted therapy, drug delivery and selective treatment making them a better substitute against traditional therapeutic agents.

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Colorectal cancer is one of the most commonly diagnosed malignancies are mainly initiated by the mutations in the wnt signalling proteins, viz., Adenomatous polyposis coli (APC), β-Catenin and glycogen synthase kinase 3 β (GSK-3 β). The present study focuses on molecular docking analysis of bioactive molecules isolated from Stoechospermum marginatum against wnt signalling proteins. Twelve bioactive molecules from S. marginatum were evaluated for their potential to interact with wnt signalling proteins. The biomolecules were screened for their in silico ADMET properties.

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In this chapter, the following content will be discussed: Distinctive properties of living systems, biomolecules: molecules of life, biomolecular hierarchy, properties of biomolecules, organization and structure of cells, viruses as cell parasites.

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Chapter 3 introduce the Thermodynamics of biological systems. The following will be discussed in this chapter: Basic thermodynamic concepts, physical significance of thermodynamic properties, pH and the standard state, the effect of concentration, coupled processes, high-energy biomolecules.

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Biomolecule–nanoparticle (NP) [or quantum-dot (QD)] hybrid systems combine the recognition and biocatalytic properties of biomolecules with the unique electronic, optical, and catalytic features of NPs and yield com-posite materials with new functionalities.

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Carbon-based nanoparticles and nanostructures, such as carbon nanotubes (CNTs), have drawn great attention in both academia and industry due to their wide potential applica‐ tions. Owing to their well-defined one-dimensional (1D) interior, CNTs serve as desirable materials for encapsulating molecules, such as water [1-4], ionic liquid [5], drug molecules [6], and biomolecules [7].

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The invention of scanning tunneling microscope (STM) by Binnig and his colleagues in 1982 opened up the possibility of imaging material surfaces with spatial resolution much superior to the conventional microscopy techniques. The STM is the first instrument capable of directly obtaining three-dimensional images of solid surfaces with atomic resolution. Even though STM is capable of achieving atomic resolution, it can only be used on electrical conductors. This limitation has led to the invention of atomic force microscope (AFM) by Binnig and his co-workers in 1986.

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the micro- and nano- transport of biomolecules is of interest to a wide range of scientific and engineering communities. application areas include miniaturized technology that will support and advance key sectors, including healthcare, food provisioning, environment services, etc. this is generally intended for undergraduate students from chemical, life and physical sciences wanting to find out about the basic properties of biomolecules and how they can be transported in liquids on the micro- to nano-scale.

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A rigorous understanding of any biological system that undergoes some change requires quantification of its thermodynamic and kinetic properties. Combined with structural detail, these data can be assimilated to enable a picture of the mechanism of the change (for example, going from the free to bound state in a biomolecular interaction, or from the folded to the unfolded state of a biomolecule). Isothermal titration calorimetry (ITC) and differential scanning calorimetry (DSC) provide the thermodynamic data required for developing this understanding.

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Progress in modern science is impossible without reliable tools for characterization of structural, physical, and chemical properties of materials and devices at the micro-, nano-, and atomic scale levels. While structural information can be obtained by such established techniques as scanning and transmission electron microscopy, high-resolution examination of local electronic structure, electric potential and chemical functionality is a much more daunting problem.

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