Protective immunity and vaccines

Although HPV prophylactic vaccines can provide effective immune protection against high-risk HPV infection, studies have shown that the protective effect provided by them would decrease with the increased age of vaccination, and they are not recommended for those who are not in the appropriate age range for vaccination.

11p vikoch 27-06-2024 1 1   Download

Part 1 book "Principles of fish immunology - From cells and molecules to host protection" includes content: Anatomy of teleost fish immune structures and organs; innate immunity; adaptive immunity; cellular immune responses; lymphocytes of teleosts; fish macrophages; immunoglobulins inteleost; b-cell responses and antibody repertoires in teleost fish - from ag receptor diversity to immune memory and vaccine developm; complement activation in fish with emphasis on MBL masp; cytokines and immunity.

358p muasambanhan02 25-12-2023 3 2   Download

Part 2 book "Encyclopedia of immunobiology (Vol 3 - Activation of the immune system)" includes content: TNF and TNFR family members and B cell activation, cytokine-Producing effector B cells, vaccines to program protective humoral immunity, B cell leukemia and lymphoma, modification of T cell functions at sites of infection and inflammation,...and other contents.

278p oursky06 17-10-2023 7 3   Download

The poultry industry in Vietnam is vulnerable to many viral diseases. Since antibiotics and vaccination provide inadequate protection, it will be beneficial to have alternative immunostimulants to boost non-specific immunity in poultry. Chicken interferon-alpha (ChIFNα) has been described previously with antiviral activity against many pathogens.

9p vicaptainmarvel 21-04-2023 4 2   Download

Glaesserella parasuis, the causative agent of Glӓsser’s disease, is widespread in swine globally resulting in significant economic losses to the swine industry. Prevention of Glӓsser’s disease in pigs has been plagued with an inability to design broadly protective vaccines, as many bacterin based platforms generate serovar or strain specific immunity.

9p vigandhi 23-02-2022 11 1   Download

Foot-and-mouth disease (FMD) is a highly transmissible disease that leads to vast economic losses in many countries. Prevention using inactivated vaccines is one effective measure used to control FMD. Unfortunately, inactivated FMD vaccines provide only short-term protection and require a cold-chain system.

9p vidarwin 23-02-2022 10 1   Download

Infectious bronchitis virus (IBV), a coronavirus, is one of the most important poultry pathogens worldwide due to its multiple serotypes and poor cross-protection. Vaccination plays a vital role in controlling the disease. The efficacy of vaccination in chicken flocks can be evaluated by detecting neutralizing antibodies with the neutralization test. However there are no simple and rapid methods for detecting the neutralizing antibodies.

7p vidarwin 23-02-2022 9 1   Download

Bacillus anthracis is the causative agent of anthrax, a disease of both humans and various animal species, and can be used as a bioterror agent. Effective vaccines are available, but those could benefit from improvements, including increasing the immunity duration, reducing the shot frequency and adverse reactions. In addition, more sophisticated antigen delivery and potentiation systems are urgently required.

10p vigandhi 23-02-2022 8 1   Download

Genome editing of malaria parasites is key to the generation of live attenuated parasites used in experimental vaccination approaches. DNA repair in Plasmodium generally occurs only through homologous recombination. This has been used to generate transgenic parasites that lack one to three genes, leading to developmental arrest in the liver and allowing the host to launch a protective immune response.

18p viaristotle 29-01-2022 11 0   Download

The bacillus Calmette-Guérin (BCG) vaccine protects against tuberculosis and heterologous infections but elicits high inter-individual variation in specific and nonspecific, or trained, immune responses. While the gut microbiome is increasingly recognized as an important modulator of vaccine responses and immunity in general, its potential role in BCG-induced protection is largely unknown.

22p viarchimedes 26-01-2022 12 0   Download

Ebolavirus (EBOV) is responsible for one of the most fatal diseases encountered by mankind. Cellular T-cell responses have been implicated to be important in providing protection against the virus. Antigenic variation can result in viral escape from immune recognition. Mapping targets of immune responses among the sequence of viral proteins is, thus, an important first step towards understanding the immune responses to viral variants and can aid in the identification of vaccine targets.

13p vilarryellison 29-10-2021 15 1   Download

Hepatitis B Infection is an occupational high risk factor. Immune response for vaccination was measured by Antibody to Hepatitis B surface antigen (anti HBs) levels. A course of Hep B vaccine yields a protective immune response (anti-HBs ≥10 mIU/mL) this study was designed to determine the anti HBs levels in Health Care Workers (HCWs) working as laboratory technician and staff nurses.

7p angicungduoc6 22-07-2020 17 2   Download

Vaccination is the best method for controlling the disease and the protection of the livestock. During the vaccination, most of the animals get stressed which will influence the development of the immunity against the vaccination. The present study was conducted to evaluate the herbal anti-stressor product (Restobal® , M/s Ayurvet Limited) against the management of vaccination stress in buffaloes.

5p nguaconbaynhay5 16-05-2020 8 0   Download

Engineered vaccine proteins incorporating both antigen and adjuvant components are constructed with the aim of combining functions to induce effective protective immunity. Bacterial flagellin is a strong candidate for an engineered vaccine scaffold as it is known to provide adjuvant activity through its TLR5 and inflammasome activation.

11p vihamax2711 21-04-2020 7 0   Download

Measles is a highly contagious vaccine-preventable disease caused by the Morbilivirus. Measles vaccine was introduced in India in 1985 as a part of Universal Immunization Programme (UIP) which was given at 9 completed months of age. As vaccine coverage has increased, there has been a marked reduction in measles incidence in the pediatric age group; but at the same time, the average age, at which measles infection occurs, has significantly increased.

8p chauchaungayxua3 07-02-2020 14 3   Download

Passive transferred antibodies to the fetus play an essential role on protecting neonates and young infants until infant vaccination is more efficacious. However, very little is known about the discrepancy of DTP vaccine associated antibodies level in neonates from different economic areas in China.

7p vivalletta2711 11-01-2020 10 1   Download

Childhood vaccinations have been shown to be effective in protecting children against vaccinepreventable diseases. The systematic investigation of the causes of incomplete immunization is critical for the full immunization and develop health system interventions to improve immunization coverage.

8p virome2711 13-01-2020 13 1   Download

Schistosomiasis is a debilitating parasitic disease caused by platyhelminthes of the genus Schistosoma, notably Schistosoma mansoni, Schistosoma haematobium, and Schistosoma japonicum. Pioneer researchers used radiation-attenuated (RA) schistosome larvae to immunize laboratory rodent and non-human primate hosts. Significant and reproducible reduction in challenge worm burden varying from 30% to 90% was achieved, providing a sound proof that vaccination against this infection is feasible.

13p trinhthamhodang1 16-11-2019 18 0   Download

Uric acid is synthesized mainly in the liver, intestines and the vascular endothelium as the end product of an exogenous pool of purines, and endogenously from damaged, dying and dead cells, whereby nucleic acids, adenine and guanine, are degraded into uric acid. Mentioning uric acid generates dread because it is the established etiological agent of the severe, acute and chronic inflammatory arthritis, gout and is implicated in the initiation and progress of the metabolic syndrome.

7p trinhthamhodang1 14-11-2019 28 1   Download

Papain, an experimental model protease, was used to decipher the protective mechanism(s) of the cysteine peptidase-based schistosomiasis vaccine. To examine the role of T lymphocytes, athymic nude (nu/nu) and immunocompetent haired (nu/+) mice were subcutaneously (sc) injected with 50 mg active papain two days before percutaneous exposure to 100 cercariae of Schistosoma mansoni. Highly significant (P < 0.005) reductions in worm burden required competent T lymphocytes, while significant increases (P < 0.

12p caygaocaolon1 13-11-2019 17 2   Download