Protein molecule

Molecular targeted therapy using a drug that suppresses the growth and spread of cancer cells via inhibition of a spe‑ cifc protein is a foundation of precision medicine and treatment. High expression of the proto-oncogene Bcl-3 promotes the proliferation and metastasis of cancer cells originating from tissues such as the colon, prostate, breast, and skin.

12p vishanshan 27-06-2024 1 1   Download

The chapters are divided into 4 parts: Part I describes flagellar type III protein exports, assembly, and gene regulation in S.

318p vimeyers 29-05-2024 5 2   Download

Ebook "DNA helicases and DNA motor proteins" is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in response to different cellular stresses and are integrated into large macromolecular assemblies to form a complex and adaptive living system.

308p ladongphongthanh1008 22-04-2024 4 2   Download

Ebook "Biophysics of DNA-protein interactions: From single molecules to biological systems" would focus on the specific topic of the biophysics of DNA-protein interactions, and would include the use of new approaches, including both bulk methods as well as single molecule methods. This would make the book attractive to anyone working in the general area of DNA-protein interactions, which is of course a much wider market than just single molecule biophysicists or even biophysicists.

354p ladongphongthanh1008 22-04-2024 8 2   Download

Ebook "Membrane biophysics: New insights and methods" highlights recent advances in and diverse techniques for exploring the plasma membrane’s structure and function. It starts with two chapters reviewing the history of membrane research and listing recent advances regarding membrane structure, such as the semi-mosaic model for red blood cell membranes and the protein layer-lipid-protein island model for nucleated tissue cell membranes.

425p tracanhphuonghoa1007 22-04-2024 4 3   Download

Ebook "Targeting protein-protein interactions by small molecules" comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies of small molecule PPI inhibitors. The first part discusses various discovery strategies for small molecule PPI inhibitors, such as high throughput screening, hot spot-based design, computational approaches, and fragment-based design.

332p tracanhphuonghoa1007 22-04-2024 4 2   Download

In ebook "Single-molecule fluorescence spectroscopy of the folding of a repeat protein" single-molecule fluorescence resonance energy transfer (FRET) spectroscopy was used to study the folding of a protein that belongs to the large and important family of repeat proteins. Cohen shows that the dynamics of the expanded conformations is likely to be very fast, suggesting a spring-like motion of the whole chain. The findings shed new light on the elasticity of structure in repeat proteins, which is related to their function in binding multiple and disparate partners.

70p tracanhphuonghoa1007 22-04-2024 4 3   Download

Ebook "Chemical evolution of nitrogen-based compounds in mozzarella cheeses" summarizes how the presence of amines is influenced by different factors such as cheese variety, seasoning and microflora. The authors compare typical profiles of different products, e.g. ripe vs. unripe cheeses, focusing also on the different types of mozzarella cheeses. The Brief also introduces several analytical methods and simulation techniques, which are being used to evaluate the evolutive profiles of different selected molecules, protein aggregation, or proteolysis.

48p tracanhphuonghoa1007 22-04-2024 3 2   Download

Ebook "SUMO regulation of cellular processes (Second edition)" of a very well received book that details how the sumoylation system functions and how it modulates numerous cellular activities. SUMO is a post-translational modifier in the ubiquitin super-family that has gained recognition over the last twenty years as an essential and prevalent regulatory molecule. Individual chapters explore the biochemistry, molecular biology, and cell biology of the sumoylation system and its substrate proteins.

413p cotieubac1004 15-03-2024 1 0   Download

Ebook "Computational modeling of biological systems: From molecules to pathways" provides an overview of the established computational methods used for modeling biologically and medically relevant systems. Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to model, visualize, and rationally alter systems at various length scales, starting from molecular modeling and design at atomic resolution to cellular pathways modeling and analysis.

360p duongthandue0501 28-02-2024 6 1   Download

Ebook "Molecular mechanisms of exocytosis ((Molecular biology intelligence unit)" written by recognized experts in the field aims at clarifying for a non-specialist audience the role of the key players in the exocytotic process not only in neuronal and endocrine cells but also in a variety of other relevant cell systems. The book represents a unique collection of up-to-date reviews that will introduce researchers and students to the forefront of this rapidly moving and fascinating field.

186p duongthandue0501 28-02-2024 2 1   Download

Ebook "Fluorescent proteins II: Application of fluorescent protein technology" highlights the physicochemical and biophysical aspects of fluorescent protein technology beyond imaging. It is tailored to meet the needs of physicists, chemists and biologists who are interested in the fundamental properties of fluorescent proteins, while also focussing on specific applications. The implementations described are cutting-edge studies and exemplify how the physical and chemical properties of fluorescent proteins can stimulate novel findings in life sciences.

287p manmanthanhla0201 26-02-2024 2 1   Download

Ebook "Kinesin protocols (Methods in molecular biology, Volume 164)" present a wide range of domain organizations with a motor domain located at different positions in the molecule. Their motility properties are also variable in directionality, velocity, and such other characteristics as bundling activity and processivity. Finally, and most important, they practicipate in a multitude of cellular functions.

228p manmanthanhla0201 26-02-2024 3 1   Download

Ebook "Sample preparation in biological mass spectrometry" is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis.

1081p manmanthanhla0201 26-02-2024 2 2   Download

Ebook "Fluorescence spectroscopy in biology: Advanced methods and their applications to membranes, proteins, dna, and cells" focuses on two new approaches in cell fluorescence microscopy. R. Brock shows how to characterize diffusion in cells by fluorescence correlation spectroscopy. The last two contributions by S. Rosenthal and O. Minet are devoted to photophysics and the use of quantum dots in cell imaging.

315p manmanthanhla0201 27-02-2024 3 2   Download

Part 1 book "Molecular cell biology" includes content: Life begins with cells, chemical foundations, protein structure and function, basic molecular genetic mechanisms, biomembranes and cell architecture, integrating cells into tissues, transport of ions and small molecules across cell membranes, cellular energetics, molecular genetic techniques and genomics, molecular structures of genes and chromosomes, transcriptional control of gene expression.

490p muasambanhan07 18-02-2024 2 2   Download

Ebook "Advancements of mass spectrometry in biomedical research" explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered.

601p nhanphanguyet 28-01-2024 2 2   Download

Ebook "NMR in biological systems: From molecules to humans" caters to the needs of: (i) graduate students who mostly learn such techniques from senior post-docs in the laboratory; (ii) those who are not experts in NMR but wish to understand if a particular problem in animal, plant, medical and pharmaceutical sciences can be answered by NMR; and (iii) those who are experts in chemistry and biochemistry and wish to know how NMR can provide them information on structural or functional aspect of proteins, nucleic acids, cells and tissues, human and plant organs and other biological materials.

552p tachieuhoa 28-01-2024 8 2   Download

Ebook "Biophysical chemistry of proteins: An introduction to laboratory methods" is structured in nine sections, each containing several chapters. The volume starts with an overview of analytical techniques and progresses through purification of proteins; protein modification and inactivation; protein size, shape, and structure; enzyme kinetics; protein-ligand interactions; industrial enzymology; and laboratory quality control. The book is targeted at all scientists interested in protein research.

490p tachieuhoa 28-01-2024 6 2   Download

Ebook "Endocytosis in plants" presents an overview of our current knowledge of endocytosis in plants with a main focus on the key molecules undergoing and regulating endocytosis. It also provides up to date methodological approaches as well as principles of protein, structural lipid, sugar and microbe internalization in plant cells. The individual chapters describe clathrin-mediated and fluid-phase endocytosis, as well as flotillin-mediated endocytosis and internalization of microbes.

337p tachieuhoa 28-01-2024 7 2   Download