Protein surface

This volume focuses on the transport of medically relevant bacterial protein toxins into mammalian cells, and on novel pharmacological strategies to inhibit toxin uptake. The first chapters review our current understanding of the cell-surface receptors and cellular transport processes of Clostridium botulinum neurotoxins, Clostridium botulinum C3 toxin, Clostridium difficile toxins, binary clostridial enterotoxins, anthrax toxins and diphtheria toxin.

261p vimeyers 29-05-2024 5 1   Download

The aim of this study was to evaluate the biological activity of some pyridine derivatives (compounds 1 to 15) on perfusion pressure in an isolated rat heart model. Furthermore, theoretical interaction of pyridine derivatives with the M2 muscarinic receptor was determined using acetylcholine, AF-DX 116 and the 3uon protein as theoretical tools in a docking model.

11p dianmotminh02 03-05-2024 1 1   Download

Ebook "TNF receptor associated factors (TRAFs)" is the only literature that is entirely devoted to TRAFs. Almost every aspect of TRAF signaling is covered, including the different TRAF family members, their distinct biological functions, the TRAF structures, their modes of receptor recognition, the signaling mechanisms, and the roles of TRAFs in normal cellular functions and in viral infection.

222p ladongphongthanh1008 22-04-2024 1 1   Download

Ebook "Advances in parasitology: Reflections on a century of malaria biochemistry" provides an overview of the research that has been done in malaria biochemistry in the quest to find a cure. It discusses how our understanding has helped us to develop better diagnostics and novel chemotherapies. Researchers will find having all of this information in one volume, annotated with personal reflections from a leader in the field, invaluable given the big push being made on various fronts to use the latest drug discovery tools to attack malaria and other developing country diseases.

397p tracanhphuonghoa1007 22-04-2024 3 1   Download

Ebook "Study of the peptide–peptide and peptide–protein interactions and their applications in cell imaging and nanoparticle surface modification" focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.

103p tracanhphuonghoa1007 22-04-2024 3 3   Download

Exosomes are promising tools for improving cancer care, but conversely may also contribute to tumor progression. Here, we highlight recently discovered roles of exosomes in modulating immune responses in cancer, with emphasis on exosomal surface proteins and on RNA and DNA content. We also discuss how exosomes could be exploited as biomarkers and delivery vehicles in cancer therapy.

4p vibransone 28-03-2024 2 2   Download

Ebook "Protein-Protein interactions (Topics in Medicinal chemistry, Volume 8)" surveys the field of inhibitors of the MDM2/p53 interaction, which essentially began with the high-profile disclosure of Nutlins, and quickly and steadily grew through programs at a number of pharmaceutical companies. The MDM2/p53 interaction constitutes a paradigm example of a relatively large, hydrophobic interaction surface for which lead compounds can easily be found.

276p coduathanh1122 27-03-2024 5 1   Download

Ebook "Electrochemical analysis of proteins and cells" presents the remarkable progress made over the years in the electrochemical analysis of proteins and cells, due to the rapid development of protein electrochemistry together with related technologies such as surface modification, molecular recognition, molecular assembly, and nanotechnology.

76p coduathanh1122 27-03-2024 6 1   Download

Ebook "Nanobioelectrochemistry: From implantable biosensors to green power generation" describes some of the different electrochemical techniques that can be used to study new strategies for patterning electrode surfaces with enzymes, organelles, cells and biomimetic systems. Also, it focuses on how enzymes and microorganisms can be used as biological catalysts in fuel cells for green power generation.

144p coduathanh1122 27-03-2024 2 1   Download

Ebook "Purification of peptides in high-complexity arrays: A new method for the specific surface exchange and purification of entire peptide libraries" focuses on improving the quality of in situ synthesized high-complexity peptide micro arrays. Micro arrays containing proteins or small protein fragments in the form of peptides have become of great interest in proteomic research.

138p coduathanh1122 27-03-2024 4 1   Download

Ebook "Viral entry into host cells" for a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane. Viruses have evolved specialized surface proteins to meet this challenge. These proteins facilitate delivery of the viral genetic information into the host cell by either fusing the viral envelope with a host cell membrane or by forming membrane pores. Membrane fusion and pore formation critically depend on the engagement of host cell receptors and receptor choice is a key determinant of viral tropism.

213p cotieubac1004 15-03-2024 0 0   Download

Ebook "Analytics of Protein–DNA interactions (Advances in biochemical engineering/biotechnology, Volume 104)" focuses on the fascinating possibilities that emerged during the last years to study protein–DNA interactions in vitro. As an essential part of transcriptional activity during development and in tumorgenesis a separate chapter describing the analysis of DNA modification especially methylation of cytosines at their carbon-5 position was included.

212p manmanthanhla0201 27-02-2024 4 2   Download

Ebook "Food emulsifiers and their applications (Second edition)" has focused on the design and application of emulsifiers as versatile food ingredients. The second edition has updated and expanded applications, from both theoretical and practical perspectives. The first three chapters describe design, synthesis, analysis, and commercial preparation of emulsifiers. Synergistic and antagonistic interactions with other food ingredients, such as carbohydrates, proteins, and water, are discussed in the next three chapters.

433p manmanthanhla0201 27-02-2024 2 1   Download

Part 2 book "Molecular cell biology" includes content: Post transcriptional gene control and nuclear transport, signaling at the cell surface, signaling pathways that control gene activity, integration of signals and gene controls, moving proteins into membranes and organelles, vesicular traffic, secretion and endocytosis, metabolism and movement of lipids, microfilaments and intermediate filaments, microtubules, regulating the eukaryotic cell cycle, cell birth, lineage and death, cancer.

477p muasambanhan07 18-02-2024 5 1   Download

Ebook "Adhesive interactions of mussel foot proteins" presents recent progress in understanding the basic surface and intermolecular interactions employed by mussels to achieve strong and durable wet adhesion. The surface forces apparatus (SFA) and various other techniques were applied to measure the interactions between mussel foot protein-3 fast (Mfp-3 fast) and the model substrate, mica, as well as the interactions between various mussel adhesive proteins.

79p nhanphanguyet 28-01-2024 5 2   Download

Part 1 book "Gram-Positive pathogens" includes content: The gram positive cell wall, surface proteins on gram positive bacteria, capsular polysaccharide of group a streptococc, toxins and superantigens of group a streptococci, toxins and superantigens of group a streptococci, genetics of group a streptococci, extracellular matrix interactions with gram positive pathogens,... and other contents.

506p muasambanhan05 22-01-2024 4 2   Download

Part 2 book "Gram-Positive pathogens" includes content: Staphylococcal plasmids, transposable and integrative elements; temperate phages of staphylococcus aureus; pathogenicity islands and their role in staphylococcal biology; respiration and small colony variants of staphylococcus aureus; the staphylococcal cell wall; staphylococcal protein secretion and envelope assembly; surface proteins of staphylococcus aureus, immune evasion by staphylococcus aureus,... and other contents.

390p muasambanhan05 22-01-2024 5 2   Download

Part 1 book "Control of pig reproduction VIII" includes content: The physiological roles of the boar ejaculate, molecular kinetics of proteins at the surface of porcine sperm before and during fertilization, optimal characteristics of spermatozoa for semen technologies in pigs, recent advances in boar semen cryopreservation, selection for boar fertility and semen quality - the way ahead,... and otehr contents.

173p oursky10 04-12-2023 8 4   Download

Epstein Barr virus (EBV)-associated endemic Burkitt’s Lymphoma pediatric cancer is associated with morbidity and mortality among children resident in holoendemic Plasmodium falciparum regions in western Kenya.

12p visharma 20-10-2023 3 2   Download

The accumulation of lipid droplets (LDs) in hepatocytes is the main pathogenesis in nonalcoholic fatty liver disease (NAFLD), which is also the key risk factor for the progression of hepatocellular carcinoma (HCC). LDs behaviors are demonstrated to be associated with HCC advancement, and are tightly regulated by a subset protein localized on the surface of LDs. However, the role of LDs-localized protein in HCC has been rarely investigated.

14p vioracle 29-09-2023 3 2   Download