Public health concern globally

Carbapenem-resistant Enterobacteriaceae are considered by WHO as “critical” priority pathogens for which novel antibiotics are urgently needed. The dissemination of carbapenemase-producing Escherichia coli (CP-Ec) in the community is a major public health concern. However, the global molecular epidemiology of CP-Ec isolates remains largely unknown as well as factors contributing to the acquisition of carbapenemase genes.

18p vibransone 28-03-2024 4 2   Download

The cancer burden is a global public health concern associated with high morbidities and mortalities. Low and middle-income countries are more affected including South Africa. Limited access to oncology services contributes to the late presentation, late diagnosis, and treatment of cancer.

9p visharma 20-10-2023 6 2   Download

Vitamin A Supplementation (VAS) is a low-cost high impact, acceptable, and clinically effective intervention recommended by the World Health Organization to combat the effects of the prevalent Vitamin A deficiency in children 6-59 months which remains a public health concern globally.

9p viisac 23-09-2023 5 1   Download

Despite a global decrease in malaria burden worldwide, malaria remains a major public health concern, especially in Benin children, the most vulnerable group. A better understanding of malaria’s spatial and agedependent characteristics can help provide durable disease control and elimination.

15p viferrari 29-10-2022 2 2   Download

Access to sexual and reproductive health and rights (SRHR) information during adolescence has become a global concern. This study explored factors that enable or prevent young adolescents from accessing to SRHR information from the perspective of the key informants in Rwanda.

14p viferrari 29-10-2022 4 2   Download

Obesity and hypertension are global health concerns. Both are linked with increased risks of allcause and cardiovascular mortality. Several early studies reported the prevalence of obesity and hypertension in Bangladeshi adults, but the associated factors in this country population are not clear yet.

14p viferrari 29-10-2022 10 2   Download

Population aging has been an emerging public and health concern globally. Balance performance can be applied as an indicator of functional status and a predictor of health outcomes in the elderly. However, reference data of balance performance in the elderly generated from large scale studies have been very limited.

11p vinobelprisen 26-03-2022 17 5   Download

Tuberculosis remains a serious public health concern globally. The enormous social, economic, and health impacts of the diseases are attributed to the lack of updated data on the prevalence, geospatial distribution, population structures, and genotypic variants of the circulating M. tuberculosis.

12p vimackenziebezos 29-11-2021 8 2   Download

Diphtheria remains a major public health concern with multiple recent outbreaks around the world. Moreover, invasive non-toxigenic strains have emerged globally causing severe infections. A diphtheria epidemic in the former Soviet Union in the 1990s resulted in ~5000 deaths. In this study, we analysed the genome sequences of a collection of 93 C. diphtheriae strains collected during and after this outbreak (1996 – 2014) in a former Soviet State, Belarus to understand the evolutionary dynamics and virulence capacities of these strains.

10p vilarryellison 29-10-2021 9 0   Download

The increasing spectrum of multidrug-resistant bacteria is a major global public health concern, necessitating discovery of novel antimicrobial agents. Here, members of the genus Bacillus are investigated as a potentially attractive source of novel antibiotics due to their broad spectrum of antimicrobial activities. We specifically focus on a computational analysis of the distinctive biosynthetic potential of Bacillus paralicheniformis strains isolated from the Red Sea, an ecosystem exposed to adverse, highly saline and hot conditions.

11p vibeauty 23-10-2021 13 0   Download

Typhoid fever, caused by Salmonella Typhi, follows a fecal-oral transmission route and is a major global public health concern, especially in developing countries like Bangladesh. Increasing emergence of antimicrobial resistance (AMR) is a serious issue; the list of treatments for typhoid fever is ever-decreasing.

15p visilicon2711 20-08-2021 14 1   Download

The hepatitis E virus (HEV) is the causative pathogen of hepatitis E, a global public health concern. HEV comprises 8 genotypes with a wide host range and geographic distribution. This study aims to determine the genetic factors influencing the molecular adaptive changes of HEV open reading frames (ORFs) and estimate the HEV origin and evolutionary history.

16p viansan2711 30-07-2021 16 1   Download

Emergence of antibiotic resistance is a global public health concern. The relationships between antibiotic use, the gut community composition, normal physiology and metabolism, and individual and public health are still being defined.

18p vijeeni2711 24-07-2021 9 0   Download

Globally, tuberculosis (TB) lasts a major public health concern. Using feasible strategies to estimate TB infectious periods is crucial. The aim of this study was to determine the magnitude of TB infectious period and associated factors in East Gojjam zone.

11p vimaine2711 26-03-2021 10 2   Download

With the global spread of multi drug resistance in pathogenic microbes, infectious diseases emerge as a key public health concern of the recent time. Identification of host genes associated with infectious diseases will improve our understanding about the mechanisms behind their development and help to identify novel therapeutic targets.

12p vicolorado2711 23-10-2020 14 2   Download

Dengue is the most critical arthropod borne viral infection and a major public health concern globally in recent years infecting about 50 million people each year. Dengue infected patients present with symptoms varying from mild fever to life threatening shock. Associated thrombo cytopaenia is a hall mark of a life threatening dengue infection. A platelet count of less than 100,000/µl is a diagnostic criteria for dengue haemorrhagic fever (DHF) as per World Health Organization (WHO) guidelines, 2015.

6p nguaconbaynhay6 23-06-2020 12 0   Download

Reducing child mortality and morbidity is a public health concern globally. Like many other developing countries, Bangladesh is struggling to improve child health status as the use of medical treatment is still not at a satisfactory level.

11p viorochimaru2711 29-05-2020 22 1   Download

Human Immunodeficiency Virus (HIV) is one of the main causes of morbidity and mortality; because of this it continues to be a major global public health concern. It has believed to kill more than 34 million lives so far.

8p vimax2711 30-03-2020 6 1   Download

Cancer is a major public health concern globally and chemotherapy remains the principal mode of the treatment of various malignant diseases.

10p vienzym2711 30-03-2020 15 1   Download

Neonatal mortality remains a serious global public health problem, but Sub-Saharan Africa (SSA), in particular, is largely affected. Current evidence on neonatal mortality is essential to inform programs and policies, yet there is a scarcity of information concerning neonatal mortality in our study area.

11p vivalanbo2711 19-03-2020 10 1   Download