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Pulmonary fibrosis
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Ebook "Studies on respiratory disorders (Oxidative stress in applied basic research and clinical practice series)" covers data describing the role of free radicals and antioxidants in respiratory disorders, including the data that deal with clinical and pre-clinical trials. Chapters describe the relationship of oxidative stress to a number of respiratory and pulmonary conditions from a basic science and clinical perspective, including chronic obstructive pulmonary disease, asthma, acute lung injury, pulmonary hypertension, toxicity and fibrosis, cancer and asbestosis.
396p
manmanthanhla0201
26-02-2024
2
1
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Idiopathic pulmonary fibrosis is a disease with a poor prognosis and has been associated with increased lung cancer incidence. We report the case of a Caucasian 75-year-old woman, a former smoker, hospitalized for breathlessness with a chest computed tomography scan showing an interstitial lung disease.
4p
vilazada
31-01-2024
3
2
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In patients receiving single lung transplantation for idiopathic pulmonary fibrosis, worsening of fibrosis of the native lung is usually progressive over time, with no significant effects on gas exchange.
6p
vilazada
31-01-2024
5
2
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Ebook "Autophagy in health and disease: Potential therapeutic approaches" cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson's, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and 'bench to bedside'.
182p
lamquandat
28-12-2023
3
2
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Single nucleotide polymorphism (SNP) is a genetic variation that occurs when a single nucleotide base in the DNA sequence varies between individuals and is present in at least 1% of the population. Genetic variants in FAM13A are associated with different types of chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), and lung cancer.
9p
vioracle
29-09-2023
8
4
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This article describes two cases of patients presenting with biliary tract manifestations simulating lymphoproliferative disease and adenocarcinoma, respectively. Clinical, radiological, and histopathological findings ultimately led to the correct diagnosis, and revealed useful nuances for detection of future cases.
6p
viwhitewolf
03-07-2023
7
2
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The United States has the highest rate of maternal mortality of any developed country in the world. This excess mortality burden is related, in part, to the rising prevalence of pregnant people with chronic diseases, such as systemic lupus erythematosus, pulmonary hypertension, asthma, cystic fibrosis, diabetes, hypertension, epilepsy, chronic kidney disease, and inflammatory bowel disease.
7p
vigamora
25-05-2023
4
3
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Pulmonary actinomycosis is a chronic disease characterized by abscess formation, draining sinuses, fistulae, and tissue fibrosis. It can mimic other conditions, particularly malignant and granulomatous diseases, and is perhaps extremely challenging to diagnose.
5p
vigamora
23-05-2023
3
2
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Fibrotic idiopathic interstitial pneumonias (fIIP) are a group of fatal lung diseases with largely unknown etiology and without definitive treatment other than lung transplant to prolong life. There is strong evidence for the importance of both rare and common genetic risk alleles in familial and sporadic disease.
12p
vinarcissa
21-03-2023
1
1
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Pulmonary hypertension (PH) is a known co-morbidity in West Highland white terriers (WHWTs) affected with canine idiopathic pulmonary fibrosis (CIPF). The pulmonary vein-to-right pulmonary artery ratio (PV/ PA) has recently been described for the detection of pre-capillary PH in dogs.
7p
vidarwin
23-02-2022
8
1
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In humans with idiopathic pulmonary fibrosis (IPF), specific thoracic computed tomographic (CT) features in the correct clinical context may be used in lieu of histologic examination. Cats develop an IPF-like condition with similar features to humans.
9p
vidarwin
22-02-2022
20
2
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The mortality risk of chronic interstitial lung disease (ILD) is currently assessed using the ILD-GAP score. The present study evaluates whether the addition of cardiopulmonary ultrasound parameters to the ILD-GAP score can further improve the predictive value of ILD-GAP.
9p
vimackenziebezos
29-11-2021
7
1
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Although antifibrotic drugs, including nintedanib and pirfenidone, slow the progression of idiopathic pulmonary fbrosis (IPF), there is little data about the timing of start of antifibrotic treatment in real-world clinical practice. The present study aimed to clarify the efficacy of nintedanib and pirfenidone in patients with early-stage IPF.
10p
vimackenziebezos
29-11-2021
13
0
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Cystic fbrosis (CF) is a life-threatening multiorgan genetic disease, particularly affecting the lungs, where recurrent infections are the main cause of reduced life expectancy. In CF, mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein impair transepithelial electrolyte and water transport, resulting in airway dehydration, and a thickening of the mucus associated with abnormal viscoelastic properties.
10p
vimackenziebezos
29-11-2021
7
0
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Idiopathic Pulmonary Fibrosis is a chronic, progressive interstitial lung disease for which there is no cure. However, lung function decline, hospitalizations, and mortality may be reduced with the use of the antifibrotic medications, nintedanib and pirfenidone.
14p
vimackenziebezos
29-11-2021
9
0
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Adult patients with cystic fibrosis (CF) experience daily physical symptoms and disabilities that can be challenging to address for health care teams. Methods: We sought to identify the most frequent topics that CF adults need to discuss with health care teams using a custom questionnaire including 62 items.
8p
vimackenziebezos
29-11-2021
13
1
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Functional Respiratory Imaging (FRI) combines HRCT scans with computational fluid dynamics to provide objective and quantitative information about lung structure and function. FRI has proven its value in pulmonary diseases such as COPD and asthma, but limited studies have focused on cystic fbrosis (CF).
11p
vimackenziebezos
29-11-2021
9
1
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While lung transplant (LTX) can be an effective therapy to provide the survival benefits in selected populations, post-transplant outcome in LTX recipients with bronchiectasis other than cystic fbrosis (CF) has been less studied. Pseudomonas aeruginosa, often associated with exacerbations in bronchiectasis, is the most common micro-organism isolated from LTX recipients.
10p
vimackenziebezos
29-11-2021
9
1
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Dyskeratosis congenita (DC) is a rare genetic disorder of poor telomere maintenance. Pulmonary fbrosis (PF) related to DC is rarely reported. It is common for DC-associated PF to occur later in life without significant hematological manifestations. Mutations in the genes encoding different components of the telomere maintenance pathway were associated with clinical phenotypes and prognosis.
10p
vimackenziebezos
29-11-2021
8
1
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Interstitial lung disease is a debilitating condition associated with significant dyspnoea, fatigue, and poor exercise tolerance. Pulmonary rehabilitation is an effective and key intervention in people with interstitial lung disease.
9p
vimackenziebezos
29-11-2021
8
1
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