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Quercetin derivatives
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Several novel of polymethoxyquercetin Mannich base derivatives (2-7) were synthesized through O-methylation and based on Mannich reaction with various secondary amines and formaldehyde, starting from abundant and inexpensive natural sources quercetin.
8p
vimarillynhewson
02-01-2024
1
1
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In this study, we report the correlation between the structure and activity of flavone and the flavone derivatives that semi-synthesized and synthesized from the flower buds of the Styphnolobium japonicum (Leguminosae family) and the citrus peel, with effects against AChE. Results showed that the new functional groups of compounds Q2 and Q4 increased AChE inhibition 3 times better than quercetin. The molecular docking study was investigated in order to illuminate the experimental results and find binding modes of these prospective derivatives.
10p
spiritedaway36
25-11-2021
4
1
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Their chemical structures were characterized using HR-ESI-MS, NMR data and comparison with published data. Compounds (3, 4 & 7) were notified from the Macrosolen genus for the first time, whereas, all isolated compounds were informed for the first time from this species.
5p
nguaconbaynhay11
16-04-2021
14
2
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Staphylococcus epidermidis is one of the most multiple resistances to antibiotics in the recent years. Therefore, practically-prescribed antibiotics in the treatment of these strains are not effective. Plant-derived antibacterial is one of the most interesting sources of new therapeutics.
14p
vienzym2711
30-03-2020
18
2
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A chemical investigation of the rhizomes of Zingiber collinsii Mood & Theilade (Zingiberaceae) resulted in the isolation and identification of seven compounds, including a sesquiterpenoid (zerumbone(1)), acoumarin (scopoletin (2)), two flavonoids (quercetin (3), rutin (4)),afurfural derivative (5-(hydroxymethyl)furfural (5)), and two curcuminoids (bisdemethoxycurcumin (6),demethoxycurcumin (7)). The chemical structures of the seven compounds were determined on the basis of NMR and MS analyses.
7p
cumeo3000
01-08-2018
37
2
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Acetaldehyde, Acrylamide, Aflatoxin, Allyl isothiocyanate, Aniline, Benzaldehyde, Benzene, Benzo(a)pyrene, Benzofuran, Benzyl acetate, Caffeic acid, Catechol, Coumarin, 1,2,5,6-dibenz(a)anthracene, Estragole, Ethyl alcohol, Ethyl acrylate, Ethyl benzene, Ethyl carbamate, Furan and furan derivatives, Furfural, Heterocyclic amines, Hydrazines Hydrogen peroxide, Hydroquinone, d-limonene, 4-methylcatechol, Methyl eugenol, Psoralens, Quercetin glycosides, Safrole While this may seem frightening, the levels of these chemicals and pesticide residues found in food are too low to affect heal...
17p
cao_can
02-01-2013
60
4
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