Random walk with restart algorithm

Identifying relatedness among diseases could help deepen understanding for the underlying pathogenic mechanisms of diseases, and facilitate drug repositioning projects. A number of methods for computing disease similarity had been developed; however, none of them were designed to utilize information of the entire protein interaction network, using instead only those interactions involving disease causing genes.

13p vioklahoma2711 19-11-2020 15 2   Download

Netpredictor is an R package for prediction of missing links in any given unipartite or bipartite network. The package provides utilities to compute missing links in a bipartite and well as unipartite networks using Random Walk with Restart and Network inference algorithm and a combination of both.

10p viconnecticut2711 28-10-2020 12 0   Download

Finding underlying molecular mechanisms of diseases is one of the important issues in biomedical research. In which, prediction of novel disease-associated genes is mostly focused. Many methods have been proposed based on biological networks and shown effectively for the problem.

9p vititan2711 13-08-2019 11 1   Download