Randomly combining

Glioblastoma is the most common and most aggressive malignant primary brain tumor in adults. Glioblastoma cells synthesize and secrete large quantities of the excitatory neurotransmitter glutamate, driving epilepsy, neuronal death, tumor growth and invasion.

7p vishanshan 27-06-2024 2 1   Download

For chronic pain after thoracic surgery, optimal timing of its diagnosis and effective treatment remains unresolved, although several treatment options are currently available. We examined the efficacy and safety of mirogabalin, in combination with conventional pain therapy (nonsteroidal anti-infammatory drugs and/or acetaminophen), for treating peripheral neuropathic pain (NeP) after thoracic surgery.

15p vishanshan 27-06-2024 1 1   Download

Road traffic injuries are a major concern worldwide, with Thailand facing high accident mortality rates. Drunk driving is a key factor that requires countermeasures. Random breath testing (RBT) and mass media campaigns recommended by the World Health Organisation intend to deter such behaviour. This study aimed to evaluate the cost-effectiveness of implementing RBT in combination with mass media campaigns in Thailand.

11p vishanshan 27-06-2024 2 1   Download

Many randomized controlled trials (RCTs) and network meta-analyses have demonstrated that the progression-free survival (PFS) and overall survival (OS) of advanced non-small cell lung cancer (NSCLC) patients can be improved through combination immunotherapy or monotherapies.

9p vikoch 27-06-2024 1 1   Download

Advanced pancreatic cancer is one of the leading causes of cancer-related deaths. This prospective study aims to evaluate whether the addition of antibiotics improves the treatment efficacy of GEM/nabPTX as a first-line chemotherapy in patients with advanced pancreatic cancer.

8p vikoch 27-06-2024 1 1   Download

Anomaly detection for Internet of things (IoT) networks is a challenging issue due to the huge number of devices that connect to each other and generate huge amounts of data. In this study, we propose a model combining Autoencoder (AE) with classification algorithms to build an endto-end architecture for processing, feature extraction and data classification.

13p viambani 18-06-2024 7 1   Download

In this work, we replaced the conventional solvents such as dimethyl sulfoxide (DMSO) or dimethylformamide (DMF) by deep eutectic solvents (DES) in the synthesis of methylammonium lead iodide perovskite (MAPbI3). The first DES system was based on the combination of acetamide and urea (A–U–P system), the homogenous solution was formed at relative low temperature (~40℃). For the second system which was based on acetamide and choline chloride (A–C–P system), lead nitrate only dissolved at higher temperature (~100℃).

6p dianmotminh02 03-05-2024 4 2   Download

In this article, we introduced Bayesian Group Chain Sampling Plan (BGChSP) using different combination of parameters. In acceptance sampling plan, the random fluctuations can be describe in the selection of distribution Bayesian approach which is based on prior process history. We apply beta distribution as a suitable prior distribution. By considering consumer’s and producer’s risks, we consider Probabilistic and Indifference Quality Regions for the specified AQL and LQL. For the selection of parameters in BGChSP, Maximum Allowable Percent Defectives (MAPD) is also considered.

6p longtimenosee09 08-04-2024 1 0   Download

Ebook "An introduction to the physical chemistry of food" introduces the physical chemistry essential to understanding the behavior of foods. Starting with the simplest model of molecules attracting and repelling one another while being moved by the randomizing effect of heat, the laws of thermodynamics are used to derive important properties of foods such as flavor binding and water activity.

192p nhanphanguyet 28-01-2024 4 2   Download

The combination of taxanes and anthracyclines is still the mainstay of chemotherapy for early breast cancer. Capecitabine is an active drug with a favorable toxicity profile, showing strong anti-tumor activity against metastatic breast cancer.

11p vileonardodavinci 23-12-2023 2 2   Download

Adult eczema (AE) has been reported to have a poor quality of life (qoL). Auricular acupuncture (AA) is a method that has been studied a lot recently. Our study is to determine the effects of combining AA and modern medication in the relief of symptoms and the improvement in qoL in AE.

6p vikissinger 21-12-2023 5 1   Download

The role of adjuvant radiation in pancreatic adenocarcinoma (PDAC) remains unclear. We aimed to investigate the efficacy of gemcitabine combined with stereotactic body radiation therapy (SBRT) as adjuvant therapy for resected stage II PDAC.

7p vialfrednobel 23-12-2023 4 3   Download

The non-inferiority of dexamethasone (DEX) on day 1, with or without low-dose DEX on days 2 and 3, combined with oral NEPA (netupitant/palonosetron), compared with the guideline-consistent use of DEX was demonstrated in cisplatin. Here, we complete the analysis by assessing the impact of emesis on daily lives of patients receiving DEX-sparing regimens using the Functional Living Index-Emesis (FLIE).

8p vialfrednobel 23-12-2023 3 3   Download

Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) comprise several rare hematologic malignancies with shared concomitant dysplastic and proliferative clinicopathologic features of bone marrow failure and propensity of acute leukemic transformation, and have significant impact on patient quality of life.

15p vialfrednobel 23-12-2023 6 4   Download

Recently, the combination of the programmed death-ligand 1 (PD-L1) inhibitor atezolizumab with first-line chemotherapy has demonstrated to improve outcome for patients with advanced small cell lung cancer (SCLC), leading to approval of this regimen.

9p vialfrednobel 23-12-2023 7 3   Download

Composition of the intestinal microbiota has been correlated to therapeutic efficacy of immune check‑point inhibitors (ICI) in various cancer entities including melanoma. Prediction of the outcome of such therapy, how‑ever, is still unavailable.

11p vialfrednobel 23-12-2023 2 2   Download

Hepatitis B infection has become a social burden in over the world due to its high prevalence, while the treatments still do not offer the desired effects. Literature showed that combining traditional medicine with modern drugs was able to inhibit the proliferation of the hepatitis B virus, thus making it an effective treatment.

11p vikissinger 21-12-2023 5 2   Download

To evaluate the intravenous patient-controlled analgesic (PCA) effects of a combination of fentanyl and nefopam in patients who underwent spinal fusion surgery. Methods: 60 patients, who underwent spinal fusion surgery at the Spine Surgery Department, Military Hospital 103, from April to November 2022, were divided randomly into two groups: The F group (30 patients received fentanyl via intravenous PCA) and the NF group (30 patients received fentanyl and nefopam mixture via intravenous PCA).

12p vishekhar 31-10-2023 9 3   Download

Using texture features derived from contrast-enhanced computed tomography (CT) combined with general imaging features as well as clinical information to predict treatment response and survival in patients with hepatocellular carcinoma (HCC) who received transarterial chemoembolization (TACE) treatment.

12p vischultz 20-10-2023 2 1   Download

Soft tissue sarcomas (STS) are a rare type of malignancy comprising a variety of histological diagnoses. Chemotherapy constitutes the standard treatment for advanced STS. Doxorubicin-based regimens, which include the administration of doxorubicin alone or in combination with ifosfamide or dacarbazine, are widely accepted as first-line chemotherapy for advanced STS.

8p vischultz 20-10-2023 2 1   Download