Real-world study

Patients from non-small cell lung cancer (NSCLC) controlled clinical trials do not always reflect realworld heterogeneous patient populations. We designed a study to describe the real-world patient characteristics and treatment patterns of first-line treatment in patients in the US with NSCLC.

14p vishanshan 27-06-2024 2 1   Download

Health services worldwide face similar challenges of workforce issues to provide patient care. The findings of this study will help others to learn from Scottish experiences and provide guidance to conduct similar studies targeting healthcare reform.

12p vishanshan 27-06-2024 2 1   Download

Anti-vascular endothelial growth factor monoclonal antibody (anti-VEGF) or immune checkpoint inhibitors (ICIs) combined with chemotherapy are commonly administered to cancer patients. Although cancer patients receiving anti-VEGF or ICIs have been reported to experience an increased risk of acute kidney injury (AKI), comparative studies on the AKI incidence have not been evaluated.

9p vikoch 27-06-2024 1 1   Download

Incidence and risk factors for seizures among women with advanced breast cancer (BC) and brain metastases are not well characterized across treatment-related or clinical subtypes. This study leveraged a large realworld dataset to describe incidence and risk factors for seizures in BRCA-associated metastatic breast cancer.

12p vischultz 20-10-2023 6 1   Download

The secondary fracture prevention gap in the osteoporosis field has been previously described as a ‘crisis’. Closing this gap is increasingly important in the context of accumulating evidence showing that an incident fragility fracture is associated with an increased risk of subsequent fracture within 1–2 years, known as imminent fracture risk

10p vianttinic2711 20-04-2021 9 1   Download

A randomized clinical trial has found that the addition of erlotinib to gemcitabine (GEM-E) for pancreatic cancer led to a modest increase in survival. The aim of this national population-based retrospective study was to compare the effectiveness of GEM-E to GEM alone for pancreatic cancer patients in real clinical practice.

7p vinaypyidaw2711 26-08-2020 10 2   Download

Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II) is an efficient biomarker specific for hepatocellular carcinoma (HCC). Some researchers have proved that levels of PIVKA-II reflect HCC oncogenesis and progression. However, the effectiveness of PIVKA-II based on real-world clnical data has barely been studied.

10p vimanama2711 30-07-2020 9 1   Download

This paper analysed the real-world driving data to determine the representative parameters of driving cycle for the purpose of the typical driving cycle development of bus in Hanoi. The realworld driving data of bus in Hanoi were collected by using the Global positioning system technique with 1Hz data update rate. The real-world driving data of fifteen bus routes in the inner city were collected continuously, on weekdays as well as at weekends. The data, then, were used to calculate 33 kinematics parameters reflecting the realistic driving characteristics, including vehicle-specific power.

11p kequaidan6 11-07-2020 25 3   Download

Adjuvant chemotherapy is relatively underused in older patients with colon cancer in Japan, and its age-specific effects on clinical outcomes remain unclear. This study aimed to assess the effect of adjuvant chemotherapy on survival benefit in stage III colon cancer patients stratified by age in a Japanese real-world setting.

10p vikuala271 13-06-2020 12 1   Download

We initiate a study comparing effectiveness of the transformed spaces learned by recently proposed supervised, and semisupervised metric learning algorithms to those generated by previously proposed unsupervised dimensionality reduction methods (e.g., PCA). Through a variety of experiments on different realworld datasets, we find IDML-IT, a semisupervised metric learning algorithm to be the most effective.

5p hongdo_1 12-04-2013 68 3   Download