Recessive model

Majority of 37 human aminoacyl tRNA synthetases have been incriminated in diverse, mostly recessive, genetic diseases. In accordance with this, we uncovered a novel homozygous valyl-tRNA synthetase 1 (VARS1) gene variant, leading to p.T1068M mutation. As in the previously reported VARS1 mutations, the affected individual harboring p.T1068M was experiencing a neurodevelopmental disorder with intractable seizures, psychomotor retardation, and microcephaly.

12p lyhuyenthu 31-01-2023 7 2   Download

Brachygnathia, cardiomegaly and renal hypoplasia syndrome (BCRHS, OMIA 001595–9940) is a previously reported recessively inherited disorder in Australian Poll Merino/Merino sheep. Affected lambs are stillborn with various congenital defects as reflected in the name of the disease, as well as short stature, a short and broad cranium, a small thoracic cavity, thin ribs and brachysternum.

11p vihagrid 30-01-2023 8 3   Download

The association between CD14-159C/T polymorphism and sepsis has been assessed but results of current studies appeared conflicting and inconstant. This analysis was aimed to determine whether the CD14-159C/T polymorphism confers susceptibility to sepsis or is associated with increased risk of death from sepsis.

11p viottohahn 30-03-2022 5 1   Download

This study tests the predictive ability of the Tuckman-Chang model by applying it to charitable organizations that survived and did not survive the Great Recession, an economic event that negatively affected the charitable sector. Charitable organizations listed in the 2006 IRS Statistics of Income Exempt Organizations Sample File (SOI), hosted by the National Center for Charitable Statistics (NCCS) Data Archive, were compared to those listed in the 2011 IRS SOI File.

95p inception36 25-11-2021 29 3   Download

The symptoms of cool-temperature-induced chlorosis (CTIC) are widely existed in higher plants. Although many studies have shown that the genetic mechanism of CTIC is generally controlled by recessive genes in model plants, the dominant inheritance of albinism has not been reported thus far.

11p vijichea2711 28-05-2021 5 1   Download

Concerned by the environmental and economic threats posed by fossil fuels as the source of energy, this study uses the case of Nigeria economy to understand the extent to which economic growth and carbon emissions matters for renewable energy demands. Exploring both the linear and nonlinear ARDL modelling framework, the main empirical findings are that the amplified responsiveness of the consequence of climate change has led to increase in the demand for renewable energy particularly when the underlying source of the emissions is attributable to activities in the transport sector.

7p caygaocaolon11 18-04-2021 10 1   Download

Lecture 25: Investment - II. After studying this chapter you will be able to understand: Things that shift the investment function, why investment rises during booms and falls during recessions.

26p larachdumlanat124 28-11-2020 23 1   Download

"Ebook Rethinking housing bubbles present the content - The role of household and bank balance sheets in modeling economic cycles" present the content economic crises, economic policy, and economic analysis; goods and services markets versus asset markets; asset performance housing and the great recession; the great depression; what may have triggered or sustained the housing bubble...

310p hoangvietq2000 08-09-2020 19 1   Download

Late leaf spot caused by Phaeoisariopsis personata is the most important disease on groundnut worldwide. Although fungicide treatment is effective, it is uneconomical to use because of high cost, hazardous to environment and insensitivity build up in pathogen. The deployment of resistant cultivars is a better option to control LLS disease in groundnut the investigation was undertaken to determine the mode of genetic inheritance of LLS resistance in two F2 and F3 segregating populations of groundnut.

7p cothumenhmong3 22-02-2020 22 1   Download

Economic performance evaluation problem consists many criteria and sub criteria. Therefore it is a kind of multi-criteria decision making (MCDM) problem. It is very important for a country to monitor performance parameters in order to ensure that appropriate and timely decisions and plans can be made. Suitable performance measures can ensure that governments adopt a long-term perspective and allocate the country’s resources to the most effective activities. Fragile five (F5) countries namely Brazil, Turkey, India, Indonesia and South Africa have large and fast growing economies.

17p trinhthamhodang2 21-01-2020 58 1   Download

This paper presents an application of the split-population duration model in identifying operating strategies and structural attributes of commercial banks that increased their financial and temporal endurance (translated into probability and duration of survival, respectively) during the late 2000s recession. This study’s results identify the isolated effects of certain variables on a bank’s temporal endurance that have not been captured by other commonly used survival models.

16p trinhthamhodang2 21-01-2020 24 1   Download

The authors wanted to find out how recent financial crisis influenced performance of Croatian banks measured with ROA, ROE, NIM and Tobin's Q. Having this aim in mind, we have used many bank-specific, industry-specific or structural variables and macroeconomic variables. The analysis refers to 2007-2015 period. The research is conducted using static panel model on a balanced sample of Croatian banks listed on Zagreb Stock Exchange. The results of the analysis show that crisis dummy variable significantly influences performance but its direction is not uniform.

25p trinhthamhodang2 21-01-2020 15 1   Download

Cloud computing is a pattern for delivering ubiquitous and on demand computing resources based on pay-as-you-use financial model. Typically, cloud providers advertise cloud service descriptions in various formats on the Internet. On the other hand, cloud consumers use available search engines (Google and Yahoo) to explore cloud service descriptions and find the adequate service. Unfortunately, general purpose search engines are not designed to provide a small and complete set of results, which makes the process a big challenge.

8p trinhthamhodang1 14-11-2019 20 2   Download

Although the pathogenesis of paediatric-onset autoimmune hepatitis (pAIH) remains incompletely understood, genetic variants and environmental factors are known to be involved. Caspase recruitment domain family member 10 (CARD10) is a scaffold protein that participates in a complex pathway activating nuclear factor kappa-B (NFjB) and tumour necrosis factor alpha (TNF-a). This study aimed to investigate the association of CARD10 rs6000782 (g.37928186A > C) and TNF gene promoter rs1799724 (c.-1037C > T) variants with pAIH susceptibility in a cohort of Egyptian children.

8p trinhthamhodang1 14-11-2019 40 2   Download

The concept of change management has been evident for centuries. However, it has dramatically increased in the twenty first century as forces driving change are evolving at an increasing speed and the effects of a worldwide recession can be felt. Throughout the years organisations have put in place various methods and methodologies to manage change which include; structural, process and technological change. However, it is interesting to note that despite the fact that change is a topical subject amongst academics and consultants, only one third of all change initiatives succeed.

212p nguyenyenyn117 18-06-2019 54 7   Download

After reading this chapter, you should be able to: Define aggregate demand (AD) and explain the factors that cause it to change; define aggregate supply (AS) and explain the factors that cause it to change; discuss how AD and AS determine an economy's equilibrium price level and level of real GDP; describe how the AD-AS model explains periods of demand-pull inflation, cost-push inflation, and recession; identify how the aggregate demand curve relates to the aggregate expenditures model.

22p dien_vi03 08-10-2018 32 1   Download

After completing this chapter, students will be able to: Describe how the aggregate demand-aggregate supply model explains periods of demand-pull inflation, cost-push inflation, and recession; identify how the aggregate demand curve relates to the aggregate expenditures model.

3p dien_vi03 08-10-2018 25 1   Download

After completing this chapter, students will be able to: Explain the relationship between short-run aggregate supply and long-run aggregate supply; discuss how to apply the "extended" (short-run/long-run) AD-AS model to inflation, recessions, and economic growth;...

16p dien_vi03 08-10-2018 32 1   Download

(bq) part 1 book "macroeconomics" has contents: introduction to macroeconomics, measuring the macroeconomy, a model of production, the solow growth model, growth and ideas, the great recession - a first look, an introduction to the short run,...and other contents.

334p bautroibinhyen23 02-04-2017 40 4   Download

(bq) part 2 book "macroeconomics" has contents: monetary policy and the phillips curve, the government and the macroeconomy, international trade, exchange rates and international finance, parting thoughts, the great recession and the short run model,...and other contents.

307p bautroibinhyen23 02-04-2017 37 4   Download