Rectal cancer surgery

For patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment through the integration of radiotherapy and systemic chemotherapy before surgery, was commonly recommended as the standard treatment.

10p vishanshan 27-06-2024 1 1   Download

Local recurrence after surgery and radiochemotherapy seriously affects the prognosis of locally advanced rectal cancer (LARC) patients. Studies on molecular markers related to the radiochemotherapy sensitivity of cancers have been widely carried out, which might provide valued information for clinicians to carry out individual treatment.

8p vishanshan 27-06-2024 1 1   Download

Whether Transanal drainage tubes (TDTs) placement reduces the occurrence of anastomotic leakage (AL) after rectal cancer (RC) surgery remains controversial. Most existing meta-analyses rely on retrospective studies, while the prospective studies present an inadequate level of evidence.

12p vikoch 27-06-2024 2 1   Download

While an important surgical landmark of the dentate line has been established for locally advanced lower rectal cancer (LALRC), the prognostic significance of dentate line invasion (DLI) has not been well defined. This study aimed to explore the impact of DLI on prognosis in LALRC patients with anal sphincter involvement after neoadjuvant chemoradiotherapy followed by surgery.

12p vileonardodavinci 23-12-2023 3 3   Download

Colorectal cancer is the third most diagnosed cancer globally and the second leading cause of cancer death. We examined colon and rectal cancer treatment patterns in Australia.

13p vileonardodavinci 23-12-2023 3 3   Download

Chemoradiation therapy (CRT) followed by surgery is currently the standard of care to treat patients with locally advanced rectal cancer (LARC). CRT reduces local recurrences, but is associated with significant damage to the surrounding healthy tissue that can severely impact patients quality of life.

6p vileonardodavinci 23-12-2023 4 3   Download

Rectal cancer is one of the most lethal of gastrointestinal malignancies. Metabonomics has gradually developed as a convenient, inexpensive and non-destructive technique for the study of cancers.

13p vialfrednobel 23-12-2023 4 3   Download

Though our previous study has demonstrated that the single-incision plus one-port laparoscopic surgery (SILS+1) is safe and feasible for sigmoid colon and upper rectal cancer and has better short-term outcomes compared with conventional laparoscopic surgery (CLS), the long-term outcomes of SILS+1 remains uncertain and are needed to evaluated by an RCT. Methods Patients with clinical stage

9p vialfrednobel 23-12-2023 7 3   Download

Recent studies have shown that deficient mismatch repair (dMMR) rectal cancer may be related to treatment resistance, resulting in a worse prognosis than proficient MMR (pMMR) rectal cancer. The purpose of this study was to explore whether surgery plus other treatments (radiotherapy and chemotherapy) can bring more benefits to these patients than surgery alone.

11p vialfrednobel 23-12-2023 5 3   Download

To assess the feasibility, safe, effectiveness of laparoscopic lateral pelvic lymph node dissection (LPLD) for treatment in low rectal cancer. Subject and method: This was a prospective cohort study of rectal cancers for multidisciplinary treatment with LPLD at Department of Colon and Rectal Surgery, 108 Military Central Hospital between July 2018 and July 2019.

7p visoros 01-11-2023 3 1   Download

Neoadjuvant chemoradiation(nCRT) has been considered the preferred initial treatment strategy for distal rectal cancer. Advantages of this approach include improved local control after radical surgery but also the opportunity for organ preserving strategies (Watch and Wait-WW).

10p visharma 20-10-2023 4 2   Download

The impact of sarcopenia on the outcome of patients with left-sided colon and rectal cancer has not been exhaustively investigated. Thus, the present study was performed to evaluate the effect of sarcopenia on the outcome of patients with left-sided colon and rectal cancer.

13p vioracle 29-09-2023 7 2   Download

For locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT) may enhance tumour response, reduce recurrence, and improve patient compliance compared to upfront surgery. Recent studies have shown that chemoradiotherapy (CRT) followed by consolidation chemotherapy leads to higher rate of pathologic complete response (pCR) than induction chemotherapy followed by CRT.

7p vioracle 29-09-2023 8 2   Download

To evaluate the major outcomes of laparoscopic surgery for rectal cancer by the use of a circular side stapling technique at Military Hospital 103, Military Medical University from 1/2016 to 4/2019. Subjects and methods: A cross-sectional study was conducted on 88 patients with rectal cancer.

11p viangelamerkel 18-07-2022 5 2   Download

The ratio of serum apolipoprotein B (apoB) to apolipoprotein A-I (apoAI) had been reported as a prog‑ nostic factor in colorectal cancer. This retrospective study aimed to assess the implication of apoB-to-apoAI ratio in predicting liver metastasis from rectal cancer (RC).

8p vielonmusk 21-01-2022 13 0   Download

Many patients complain of pain following laparoscopic surgery. Clinicians have used ultrasoundguided posterior transversus abdominis plane block (TAPB) and rectus sheath block (RSB) for multimodal analgesia after surgery. We investigated the analgesic effects of US-guided posterior TAPB with RSB on postoperative pain following laparoscopy-assisted radical resection of early-stage rectal cancer.

9p vidietmarhopp 28-12-2021 14 0   Download

Total mesorectal excision (TME) and lateral lymph node dissection (LLND) without radiotherapy (RT) are standard treatment for lower cT3/4 rectal cancers in Eastern countries. In comparative studies, both TME + LLND and RT + TME yield good local control.

8p vimahuateng 26-11-2021 17 1   Download

To assess the short-term outcomes of transanal total mesorectal excision (TaTME) laparoscopic surgery for treatment of the mid and distal rectal cancer. Subjects and methods: Clinical intervention, prospective, follow-up study without comparison in 57 patients with mid and distal rectal cancer who underwent TaTME in Gastrointestinal Surgery Derpartment, Millitary Central Hospital 108, from July 2017 to December 2019.

8p vimanoban2711 13-04-2021 26 1   Download

Circumferential resection margin (CRM) and distal resection margin (DRM) have different impact on clinical outcomes after preoperative chemoradiotherapy (CRT) followed by surgery. Effect and adequate length of resection margin as well as impact of treatment response after preoperative CRT was evaluated.

9p vijennie2711 29-09-2020 14 0   Download

Neoadjuvant radiochemotherapy (RCT) is now part of the armamentarium of cancer of the lower and middle rectum. It is recommended in current clinical practice prior to surgical excision if the lesion is classified T3/T4 or N+.

8p vijennie2711 29-09-2020 16 1   Download