Regarding subtype
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Numerous studies have indicated that cancer-associated fibroblasts (CAFs) play a crucial role in the progression of colorectal cancer (CRC). However, there are still many unknowns regarding the exact role of CAF subtypes in CRC.
20p vishanshan 27-06-2024 1 1 Download
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Clear cell renal cell carcinoma (ccRCC) is the prevailing histological subtype of renal cell carcinoma and has unique metabolic reprogramming during its occurrence and development. Cell senescence is one of the newly identified tumor characteristics. However, there is a dearth of methodical and all-encompassing investigations regarding the correlation between the broad-ranging alterations in metabolic processes associated with aging and ccRCC.
23p vishanshan 27-06-2024 2 1 Download
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Ebook "Acute neuronal injury: The role of excitotoxic programmed cell death mechanisms" is the result of a convergence of scientific information regarding mechanisms that produce acute nerve cell death in the brain.
303p tracanhphuonghoa1007 22-04-2024 4 3 Download
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Pleomorphic liposarcoma is the rarest subtype of liposarcoma. Pleomorphic liposarcomas are generally unresponsive to chemotherapy and radiotherapy. Moreover, metastasis in the liver, as the first and sole site, from a primary extremity soft tissue sarcoma, including pleomorphic liposarcoma, is extremely rare. Information regarding the appropriate management of these lesions is limited.
5p vitiki 30-01-2024 4 2 Download
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KRAS-mutated non-small cell lung cancer (NSCLC) accounts for 23–35% and 13–20% of all NSCLCs in white patients and East Asians, respectively, and is therefore regarded as a major therapeutic target. However, its epidemiology and clinical characteristics have not been fully elucidated because of its wide variety of mutational subtypes.
9p vileonardodavinci 23-12-2023 4 2 Download
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Triple-negative breast cancer (TNBC) is a heterogenous subtype involving different patterns of behavior and clinical course, demanding a complex, individualized sequence of treatment. The knowledge and attitudes of the affiliated members of the Brazilian Society of Mastology regarding TNBC were evaluated and a consensus regard‑ ing management and treatment was reached.
12p vileonardodavinci 23-12-2023 5 2 Download
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Villous adenoma is the one subtype of adenomatous polyp that is very uncommon in the stomach. Data regarding clinical characteristics, natural history, and prognosis were scarce. This report presented an 87-year-old Thai woman with a large gastric villous adenoma incidentally revealed in a computed tomography of chest for the evaluation of right pleural effusion.
5p vidoctorstrange 06-05-2023 3 2 Download
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Chromatin state provides a clear decipherable blueprint for maintenance of transcriptional patterns, exemplifying a mitotically stable form of cellular programming in dividing cells. In this regard, genomic studies of chromatin states within cancerous tissues have the potential to uncover novel aspects of tumor biology and unique mechanisms associated with disease phenotypes and outcomes.
15p vielonmusk 21-01-2022 10 0 Download
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Different pathological subtypes of invasive pulmonary adenocarcinoma (IPA) have different surgical methods and heterogeneous prognosis. It is essential to clarify IPA subtypes before operation and high-resolution computed tomography (HRCT) plays a very important role in this regard.
10p vimahuateng 26-11-2021 7 1 Download
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Factors that may increase the risk for delirium and the firm knowledge around mechanism for delirium in noninvasive ventilation (NIV) patients is lacking. We investigated the incidence, characteristics, and outcomes of delirium in NIV patients.
8p vijichoo2711 31-05-2021 4 1 Download
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While numerous subpopulations of BM-MSCs have been identified, the relevance of these findings regarding the functional properties remains mostly unclear. With regards to attempts of enhancing differentiation results by preselecting certain MSC subtypes, we have evaluated the efficiency of CD146 purification during expansion, and evaluated whether these measures enhanced MSC differentiation results.
10p viannito2711 20-04-2021 9 2 Download
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Studies have reported the subtypes of individuals with knee osteoarthritis (OA) attempting to cluster this heterogonous condition. Activity limitations are commonly used to set goals in knee OA management and better identify subgroups based on level of disability in this patient population.
8p vimariana2711 22-12-2020 14 2 Download
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Methylation of HIN-1 is associated with poor outcomes in patients with ovarian clear cell carcinoma (OCCC), which is regarded to be an aggressive, chemo-resistant histological subtype. This study aimed to evaluate whether 5-aza-2-deoxycytidine (5-aza-2-dC) can reverse methylation of the HIN-1 gene to restore chemo-sensitivity of OCCC and the possible mechanism.
12p vimoscow2711 29-08-2020 17 0 Download
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The term triple-negative breast cancer (TNBC) is used to describe breast cancers without expression of estrogen receptor, progesterone receptor or HER2 amplification. To advance targeted treatment options for TNBC, it is critical that the subtypes within this classification be described in regard to their characteristic biology and gene expression.
13p vikuala271 13-06-2020 10 0 Download
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The present panorama of communication features the co-employment of language and other semiotic resources. This paper addresses this fledging field, multimodal discourse analysis, by investigating a genre targeted at children. Specifically, it studies how meanings in comics for children are constructed both verbally and visually. The data for the study is one comic - Little Red Riding Hood, which is presented via colored images and verbal texts in English.
12p quenchua1 11-11-2019 28 0 Download
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Histones are proteins that protect DNA from restriction enzymes and also act as bolsters in chromosome condensation, (Ito, 2007). A “Histone Core”, made of nine types of histone proteins, is attached to DNA molecules whose length varies from 146bp to 148bp. In the histone core, a combination of modifications, within specific amino acids in each histone subtype leads to gene expression or inactivation, (Kouzarides, 2007).
292p yeutinh98 22-09-2012 59 5 Download