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Regulate homeostasis
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Transforming growth factor-β (TGF-β) is a cytokine with multiple functions, including cell growth regulation, extracellular matrix production, angiogenesis homeostasis adjustment and et al. TGF-β pathway activation promotes tumor metastasis/progression and mediates epithelial-mesenchymal transmission suppressing immunosurveillance in advanced tumors.
13p
vishanshan
27-06-2024
2
1
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Peroxisome proliferator-activated receptor gamma (PPARG) is a member of the nuclear receptor family. It is involved in the regulation of adipogenesis, lipid metabolism, insulin sensitivity, vascular homeostasis and inflammation.
12p
vikoch
27-06-2024
1
1
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Ebook "Molecular biology of metal homeostasis and detoxification: From microbes to man" brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription.
519p
ladongphongthanh1008
22-04-2024
7
2
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Ebook "Copper and bacteria: Evolution, homeostasis and toxicity" summarizes the current knowledge of copper toxicity, homeostasis and resistance in bacteria, in which proteins like copper ATPases, copper chaperones and copper-responsive regulators of gene expression play major roles. The author also discusses the metallation of cuproenzymes. The evolution of the use of copper by cells and of copper-homeostatic proteins are is also considered in this brief.
99p
tracanhphuonghoa1007
22-04-2024
2
2
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The interplay of epigenetic processes and the intestinal microbiota may play an important role in intestinal development and homeostasis. Previous studies have established that the microbiota regulates a large proportion of the intestinal epithelial transcriptome in the adult host, but microbial effects on DNA methylation and gene expression during early postnatal development are still poorly understood.
15p
vibransone
28-03-2024
3
1
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The liver X receptors (LXRs, NR1H2 and NR1H3) and peroxisome proliferator-activated receptor gamma (PPARG, NR1C3) nuclear receptor transcription factors (TFs) are master regulators of energy homeostasis. Intriguingly, recent studies suggest that these metabolic regulators also impact tumor cell proliferation.
16p
vioraclene
31-03-2024
5
2
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Ebook "Bone morphogenetic proteins: Systems biology regulators" focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders.
448p
cotieubac1004
15-03-2024
3
0
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Part 2 book "Integrated principles of zoology" includes content: Trilobites, chelicerates and myriapods; crustaceans; hexapods; chaetognaths, echinoderms and hemichordates; chordates; fishes; early tetrapods and modern amphibians; amniote origins and nonavian reptiles; birds; mammals; support, protection, and movement; homeostasis - osmotic regulation, excretion, and temperature regulation; homeostasis - internal fluids and respiration.... and other contents.
495p
muasambanhan05
16-01-2024
1
0
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Ebook "Cellular quiescence: Methods and protocols" explores methods and protocols that aim to increase our understanding of how cells enter a quiescent state during homeostasis and how cells exit quiescence and re-enter differentiating cell divisions to restore damaged tissues, essential for developing new approaches in regenerative medicine in the future.
301p
lucchinguyen
28-12-2023
8
2
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Ebook "Cholesterol homeostasis: Methods and protocols" provides state-of-the-art techniques for studying various aspects of cholesterol homeostasis, including its uptake, synthesis and efflux from the cell, as well as its trafficking within the cell. Chapters also cover techniques for studying the regulation of cholesterol homeostasis at both the transcriptional and post-translational levels, as well as studying the membrane topology and structure of cholesterol-related proteins.
298p
lucchinguyen
28-12-2023
7
2
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Breast cancer is the most common female tumors arising worldwide, and genetic and epigenetic events are constantly accumulated in breast tumorigenesis. The melastatin-related transient receptor potential 7 channel (TRPM7) is a nonselective cation channel, mainly maintaining Zn2+, Ca2+ and Mg2+ homeostasis. It is also involved in regulating proliferation and migration in various cancers including breast cancer.
10p
vialfrednobel
23-12-2023
5
4
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Pancreatic cancer is a highly lethal disease with no effective treatments. Lactobacillus casei (L. casei) and Lactobacillus reuteri (L. reuteri) exhibited therapeutic effects on several cancers, but their roles in pancreatic cancer are unknown. This study aims to explore how L. casei & L. reuteri influence pancreatic cancer and the underlying mechanisms.
14p
vialfrednobel
23-12-2023
2
2
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Part 3 book "Berne and levy physiology" includes content: elements of renal function; solute and water transport along the nephron - tubular function; control of body fluid osmolality and volume; potassium, calcium, and phosphate homeostasis; role of the kidneys in the regulation of acid base balance; introduction to the endocrine system; hormonal regulation of energy metabolism; hormonal regulation of calcium and phosphate metabolism; the hypothalamus and pituitary gland,... and other contents.
413p
oursky07
24-10-2023
4
1
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Leucine-rich pentatricopeptide repeat containing (LRPPRC) is a potential oncogene in multiple tumor types, including lung adenocarcinoma, esophageal squamous cell carcinoma and gastric cancer. LRPPRC exerts its tumor-promoting effects mainly by regulating mitochondrial homeostasis and inducing oxidative stress.
11p
visharma
20-10-2023
4
2
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Apoptosis or programmed cell death plays a vital role in maintaining homeostasis and, therefore, is a tightly regulated process. Deregulation of apoptosis signalling can favour carcinogenesis. Apoptosis inhibitor 5 (Api5), an inhibitor of apoptosis, is upregulated in cancers. Interestingly, Api5 is shown to regulate both apoptosis and cell proliferation.
17p
visharma
20-10-2023
3
3
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Part 2 book "Vertebrate endocrinology" includes content: Comparative aspects of vertebrate adrenals, the endocrinology of mammalian reproduction, comparative aspects of vertebrate reproduction, chemical regulation of feeding, digestion and metabolism, comparative aspects of feeding, digestion, and metabolism, regulation of calcium and phosphate homeostasis in vertebrates.
286p
oursky05
20-09-2023
3
1
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In this study, we conducted the sequence polymorphisms analysis in the OsHKT1;5 coding region in order to detect the potential allelic variants in some local rice cultivars in Viet Nam. In silico analysis of protein structure and post-translational modifications indicated that amino acid substitutions had no influence on protein structure but led to changes in post-translational modifications such as phosphorylation and SUMOylation.
14p
vimulcahy
18-09-2023
4
3
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Low serum magnesium levels have been associated with multiple chronic diseases. The regulation of serum magnesium homeostasis is not well understood. A previous genome-wide association study (GWAS) of European ancestry (EA) populations identified nine loci for serum magnesium.
9p
vinarcissa
21-03-2023
5
1
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Circadian rhythms regulate key biological processes and the dysregulation of the intrinsic clock mechanism affects sleep patterns and obesity onset. The CLOCK (circadian locomotor output cycles protein kaput) gene encodes a core transcription factor of the molecular circadian clock influencing diverse metabolic pathways, including glucose and lipid homeostasis.
10p
vinarcissa
21-03-2023
1
1
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HFE, a major regulator of iron (Fe) homeostasis, has been suggested to be under positive selection in both European and Asian populations. While the genetic variant under selection in Europeans (a non-synonymous mutation, C282Y) has been relatively well-studied, the adaptive variant in Asians and its functional consequences are still unknown.
11p
vinarcissa
21-03-2023
8
1
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