Residual tumour
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Response guided treatment in breast cancer is highly desirable, but the effectiveness is only estab‑ lished based on residual cellularity from histopathological analysis after surgery. Tubule formation, a key component of grading score, is directly associated with cellularity, with significant implications on prognosis.
12p vikolindagrabar 27-07-2022 5 1 Download
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Few studies have addressed colon cancer surgery outcomes in an unselected cohort of octogenarian patients. The present study aimed to evaluate the relative survival of octogenarian patients after a major resection of colon cancer with a curative intent.
15p viangelamerkel 27-07-2022 2 1 Download
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The recommended treatment for patients with non-metastatic muscle-invasive bladder cancer (MIBC) is neoadjuvant chemotherapy (NAC) and radical cystectomy (RC). Following NAC, 20–40% of patients experience a complete pathological response (pCR) in the RC specimen and these patients have excellent long-term overall survival.
11p vimahuateng 26-11-2021 6 1 Download
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We assessed visual residual tumour cells (VRTC) with both Becker’s tumour regression grading (TRG) system and Japanese TRG system in esophageal squamous cell carcinoma (ESCC) patients treated with neoadjuvant therapy followed by surgery.
10p vianrose2711 27-04-2021 15 1 Download
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The JAK2 V617F mutation is the most frequent somatic change in myeloproliferative neoplasms, making it an important tumour-specific marker for diagnostic purposes and for the detection of minimal residual disease.
13p vijennie2711 29-09-2020 15 1 Download
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To access the clinical and subclinical response of patients with pituitary adenoma by Gamma knife in Choray Hospital. Subjects and methods: A clinical, intervention study with no control group on 81 patients with definite diagnosis of recurrent or residual pituitary adenoma at Gamma Knife Unit, Choray Hospital from January 2012 to December 2016. Results: 23 patients with functioning tumours and 58 patients with nonfunctioning tumours. The average age was 43.35 ± 11.98 years, the youngest was 18, the oldest was 73 years old. Average volume of pituitary adenoma was 5,553.73 ± 2,991.15 mm3 .
9p caygaolon 31-10-2019 24 1 Download
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a-Sarcin, a cyclizing ribonuclease secreted by the mould Aspergillus giganteus, is one of the best characterized members of a family of fungal ribotoxins. This protein induces apoptosis in tumour cells due to its highly specific activity on ribosomes. Fungal ribotoxins display a threedimensional protein fold similar to those of a larger group of microbial noncytotoxic RNases, represented by RNases T1 and U2.
7p system191 01-06-2013 24 2 Download
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Nitric oxide (NO • ) strongly inhibits the proliferation of human A431 tumour cells. It also inhibits tyrosine phos-phorylation of a 170-kDa band corresponding to the epidermal growth factor receptor (EGFR) and induces the phosphorylation at tyrosine residue(s) of a 58-kDa protein which we have denoted NOIPP-58 (nitric oxide-induced 58-kDa phosphoprotein). The NO • -induced phosphoryla-tion of NOIPP-58 is strictly dependent on the presence of EGF. Phosphorylation of NOIPP-58 and inhibition of the phosphorylation of the band corresponding to EGFR are both cGMP-independent processes. ...
10p fptmusic 16-04-2013 27 2 Download