Reversibility of glycolysis

Carbohydrate Metabolism: Glycolysis, Citric acid cycle, Gluconeogenesis, Glycogen metabolism. Invite you to consult for additional documents for the academic needs and research.

22p kimtuoi2410 22-09-2015 59 2   Download

Glucose-6-phosphate isomerase catalyzes the reversible aldose-ketose isomerization of D-glucose-6-phosphate to D-fructose-6-phosphate in glycolysis and gluconeogenesis, and in the recycling of hexose-6-phosphate in the pentose phosphate pathway. The unicellular protozoans,Trypan-osoma brucei, T. cruziandLeishmaniaspp., of the order Kinetoplastida are important human parasites responsible for African sleeping sickness, Chagas’ disease and leish-maniases, respectively. In these parasites, glycolysis is an important (and in some cases the only) metabolic pathway for ATP supply....

8p dell39 03-04-2013 37 3   Download

Phosphoglycerate kinase (EC 2.7.2.3) catalyzes reversible phosphoryl trans-fer from 1,3-bisphosphoglycerate to ADP to synthesize 3-phosphoglycerate and ATP during glycolysis. Phosphoglycerate kinases from several sources can use GDP⁄GTP as alternative substrates to ADP⁄ATP; however, the maximal velocities (Vm) reached with the guanine nucleotides are 50% of those displayed with the adenine nucleotides.

11p viettel02 22-02-2013 31 3   Download