Risk regulation

Ovarian cancer (OC) is a gynecological malignancy tumor with high recurrence and mortality rates. Programmed cell death (PCD) is an essential regulator in cancer metabolism, whose functions are still unknown in OC. Therefore, it is vital to determine the prognostic value and therapy response of PCD-related genes in OC.

17p vishanshan 27-06-2024 1 1   Download

Colorectal cancer (CRC) is a worldwide health concern. Chronic inflammation is a risk factor for CRC, and interleukin-6 (IL-6) plays a pivotal role in this process. Arginine-specific mono-ADP-ribosyltransferase-1 (ART1) positively regulates inflammatory cytokines.

13p vishanshan 27-06-2024 1 1   Download

This study aims to identify functionally relevant lncRNAs impacting OS proliferation and lipid metabolism and seeks to shed light on the upstream regulatory mechanisms governing lipogenic enzyme activity. Based on comprehensive bioinformatic analysis and the establishment of a risk model, we identified seven lncRNAs signifcantly associated with clinical characteristics and lipid metabolism-related genes in patients with OS.

15p vikoch 27-06-2024 1 1   Download

Ebook "Regulating chemical risks: European and global challenges" provides readers with contents including: chemical risk assessment and risk communication; chemical risk assessment in toxicological perspective; chemical regulation - politics, policy and management; global trends in chemicals management; regulatory futures in retrospect;...

347p giangdongdinh 28-05-2024 1 1   Download

The present paper studies the insufficiently studied problem of creating a conceptual apparatus for the practice of interaction between enterprises of the real and virtual sectors of the economy. The author sets a goal to analyze various aspects of this problem and formulate a number of concepts expanding and clarifying the system of ideas about the interaction of the real and virtual sectors of the economy.

5p longtimenosee10 26-04-2024 1 1   Download

Ebook "Food supplements containing botanicals: Benefits, side effects and regulatory aspects (The scientific inheritance of the EU project PlantLIBRA)" provides a detailed analysis of the scientific, technical and regulatory aspects of plant food supplements designed for integration into the normal diet. Each contributor is involved in the European Plant LIBRA project, and the chapters summarize the results of the project while integrating further research on botanical supplements.

474p tracanhphuonghoa1007 22-04-2024 2 2   Download

The 2023 series of bank collapses has underscored the vital importance of effective liquidity risk management in the banking industry. Liquidity risk in bank, with its potential to trigger bank runs and destabilize the global financial system, requires a comprehensive approach that considers market volatility, regulatory changes, and evolving business models. Collaboration among banks, regulators, and stakeholders is crucial at the system level.

12p longtimenosee09 08-04-2024 4 1   Download

In this paper, the author studies the impact of capital adequacy ratio on credit performance of Vietnamese commercial banks for both growth and credit risk aspects. Evaluate in detail and compare the difference of this relationship between commercial banks with different characteristics. Proposing a number of recommendations to help bank administrators and regulators be more proactive when assessing the impact of capital adequacy ratio on the individual characteristics of each bank.

10p longtimenosee09 08-04-2024 3 1   Download

One of the main trends in the law development is its digitalization under the supply chain strategies, which is manifested both in the digitalization of legal regulation, legal technologies, legal processes and law enforcement. In the emergence of regulations affecting the issues of the digital economy, electronic state, information security.

6p longtimenosee09 08-04-2024 4 0   Download

The etiology of ASD involves both inherited and environmental risk factors, with epigenetic processes hypothesized as one mechanism by which both genetic and non-genetic variation influence gene regulation and pathogenesis. The aim of this study was to identify DNA methylation biomarkers of ASD detectable at birth.

13p vibransone 28-03-2024 2 2   Download

Genome-wide association studies have identified over 160 loci that are associated with coronary artery disease. As with other complex human diseases, risk in coronary disease loci is determined primarily by altered expression of the causal gene, due to variation in binding of transcription factors and chromatin-modifying proteins that directly regulate the transcriptional apparatus.

18p vibransone 28-03-2024 4 1   Download

Ebook "Foods of non-animal origin: Chemistry, technology, inspection procedures" discusses aspects of the increasingly complex production of legal and reliable food products of non-animal origin. It introduces to the Food Safety Modernization Act (FSMA) in the USA (from January 2011), which requires the food industry to follow risk-based approaches with stronger self-regulation of food safety through measures such as the foreign supplier verification programs (FSVPs).

61p tudohanhtau1006 29-03-2024 5 1   Download

Genome-wide association studies (GWAS) have identified more than 100 genetic loci associated with type 2 diabetes (T2D). However, the underlying biological mechanisms for many of these associations remain unknown. GWAS signals close to the glucokinase regulatory protein gene (GCKR) have been reported for lipid and glucose metabolism traits and the risk of T2D.

14p vioraclene 31-03-2024 2 2   Download

Worldwide, over 350 million people are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing progressive liver diseases. The confinement of HBV replication to the liver, which also acts as the central hub for metabolic and nutritional regulation, emphasizes the interlinked nature of host metabolism and the disease.

13p vioraclene 31-03-2024 6 2   Download

The bromodomain containing 1 (BRD1) gene has been implicated with transcriptional regulation, brain development, and susceptibility to schizophrenia and bipolar disorder. To advance the understanding of BRD1 and its role in mental disorders, we characterized the protein and chromatin interactions of the BRD1 isoforms, BRD1-S and BRD1-L.

20p vioraclene 31-03-2024 3 1   Download

Ebook "Risk regulation in non-animal food imports: The European union approach" aims at providing a general understanding of the rationale – scientific as well as political – behind EU policy and related risk management decisions in the area on non-animal food imports. Lately, various menaces associated with imported food and feed of non-animal origin appeared in the media: imported sprout seeds contaminated with E. coli, strawberries containing hepatitis A or noro viruses, to name but a few, are now as much discussed as the different well-known meat scandals.

109p tudohanhtau1006 29-03-2024 3 1   Download

The aim of this research is to explore socioeconomic risks and challenges, in the modern globalized production landscape from an end-to-end supply chain perspective. Given the sensitivity of a Russian regional economy contribution to its supply chains, any improvement in supply chains strategy will be beneficial for mines and their stakeholders.

8p longtimenosee06 27-03-2024 5 2   Download

Squamous cell carcinoma (SqCC) is a subtype of non-small cell lung cancer for which patient prognosis remains poor. The extracellular matrix (ECM) is critical in regulating cell behavior; however, its importance in tumor aggressiveness remains to be comprehensively characterized.

29p viellison 28-03-2024 4 2   Download

In ebook "Microbial food safety: An introduction" some of the most qualified scientists review different food safety topics, ranging from emerging and reemerging foodborne pathogens, food regulations in the USA, food risk analysis and the most important foodborne pathogens based on food commodities. This book provides the reader with the necessary knowledge to understand some of the complexities of food safety.

260p coduathanh1122 27-03-2024 5 1   Download

Hearing problems (HP) in adults are common and are associated with several comorbid conditions. Its prevalence increases with age, reflecting the cumulative effect of environmental factors and genetic predisposition. Although several risk loci have been already identified, HP biology and epidemiology are still insufciently investigated by large-scale genetic studies.

18p vicwell 29-02-2024 3 1   Download