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RNA velocity
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Single-cell technologies are transforming biomedical research, including the recent demonstration that unspliced pre-mRNA present in single-cell RNA-Seq permits prediction of future expression states.
22p
viarchimedes
26-01-2022
6
0
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Emerging single-cell technologies profile multiple types of molecules within individual cells. A fundamental step in the analysis of the produced high-dimensional data is their visualization using dimensionality reduction techniques such as t-SNE and UMAP.
9p
viarchimedes
26-01-2022
16
0
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The simultaneous quantification of protein and RNA makes possible the inference of past, present, and future cell states from single experimental snapshots. To enable such temporal analysis from multimodal single-cell experiments, we introduce an extension of the RNA velocity method that leverages estimates of unprocessed transcript and protein abundances to extrapolate cell states.
6p
viarchimedes
26-01-2022
10
0
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The present study examined the effects of 24-h and 72-h NaCl treatment on germination, germination velocity, and the associated biochemical changes in protein and RNA contents of 2 seed morphs, and compared these effects after transfer into distilled water or 10 mM thiourea solution.
9p
vitamix
15-02-2019
18
1
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