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RNAi pathways
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Homologous recombination (HR) is the primary pathway for repairing double-strand DNA breaks implicating in the development of cancer. RNAi-based knockdowns of BRCA1 and RAD51 in this pathway have been performed to investigate the resulting transcriptomic profiles.
15p
vioraclene
31-03-2024
3
2
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RNA interference (RNAi) is a highly conserved, sequence-specific gene silencing mechanism present in Eukaryotes. Three RNAi pathways are known, namely micro-RNA (miRNA), piwi-interacting RNA (piRNA) and short interfering RNA (siRNA). However, little knowledge exists about the proteins involved in these pathways in Acari.
16p
vijeeni2711
30-06-2021
13
1
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The AMP-activated protein kinase (AMPK) is an intracellular fuel sensor for lipid and glucose metabolism. In addition to the short-term regulation of metabolic enzymes by phosphorylation, AMPK may also exert long-term effects on the transcription of downstream genes through the regulation of transcription factors and coactivators.
13p
vijeeni2711
30-06-2021
7
1
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The RNA interference (RNAi) pathway is a gene regulation mechanism that utilizes small RNA (sRNA) and Argonaute (Ago) proteins to silence target genes. Our previous work identified a functional RNAi pathway in the protozoan parasite Entamoeba histolytica, including abundant 27 nt antisense sRNA populations which associate with EhAgo2–2 protein.
18p
vilichoo2711
25-06-2021
10
0
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RNA interference (RNAi) regulates gene expression in most multicellular organisms through binding of small RNA effectors to target transcripts. Exploiting this process is a popular strategy for genetic manipulation and has applications that includes arthropod pest control.
11p
vilichoo2711
25-06-2021
10
1
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Banana is a tropical fruit with a high economic impact worldwide. Cold stress greatly affects the development and production of banana. In the present study, we investigated the functions of MaMAPK3 and MaICE1 involved in cold tolerance of banana. The effect of RNAi of MaMAPK3 on Dajiao (Musa spp. ‘Dajiao’; ABB Group) cold tolerance was evaluated.
18p
vijichea2711
28-05-2021
5
1
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RNA interference (RNAi) pathway is a gene silencing process during which small double-stranded RNA (dsRNA) molecules trigger the degradation of homologous RNA targets. Small interfering RNAs (siRNAs) are the mediators of the RNAi that can be induced in vitro and in vivo by direct application of chemically synthesized siRNAs.
6p
vivant2711
01-02-2019
27
0
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RNomics is a newly emerging sub-discipline of genomics that categorically studies the structure, function and processes of non-coding ribo nucleic acids in a cell. MicroRNomics is a sub-field of RNomics that describes the biogenesis and mechanisms of tiny RNA regulators, and their involvement in the processes of development, differentiation, cell proliferation, cell death, chromosomal segregation and metabolism. The discovery of microRNAs in species ranging from Caenorhabditis elegans (C.
580p
hyperion75
18-01-2013
60
7
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Trong vòng 10 năm trở lại đây kể từ sau khi các nhà sinh học phân tử khám phá ra cơ chế kiềm hãm sự biểu hiện gene đặc hiệu nào đó thông qua RNA – gọi là con đường gây nhiễu gene thông qua RNA (the RNA interference (RNAi) pathway) – việc nghiên cứu cơ chế và ứng dụng này ngày càng trở nên một vấn đề lý thú thu hút khá nhiều sự quan tâm của các nhà sinh học góp phần tạo nên cơn sốt "thế giới RNA – RNA World". ...
14p
heoxinhkute4
28-09-2010
158
20
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