Salivary gland proteins
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To combat malaria transmission, the Ugandan government has embarked upon an ambitious programme of indoor residual spraying (IRS) with a carbamate class insecticide, bendiocarb. In preparation for this campaign, we characterized bendiocarb resistance and associated transcriptional variation among Anopheles gambiae s.s. mosquitoes from two sites in Uganda.
12p vibeauty 23-10-2021 3 0 Download
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Salivary gland cancer (SGC) is one of the common malignancies of the head and neck area. It develops in the minor and major salivary glands and sometimes metastasizes to other organs, particularly to the lungs. Inhibitors of differentiation (Id) proteins are negative regulators of basic helix-loop-helix transcription factors that control malignant cell behavior and tumor aggressiveness in many tissues.
8p vijisoo2711 29-09-2020 12 1 Download
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Treatment options for advanced head and neck adenoid cystic carcinoma (AdCC) are limited. Prostate-Specific Membrane Antigen (PSMA), a transmembrane protein that is known for its use in diagnostics and targeted therapy in prostate cancer, is also expressed by AdCC.
9p vikuala271 13-06-2020 15 1 Download
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Ticks are economically devastating arthropod ectoparasites of livestock that exclusively feed on host blood. Ticks saliva is a crucial weapon against host-defense systems. Several small fragmented attempts are made by researchers to characterize these biomolecules. Being extremely small in size and quantity, numerous such molecules escape the deep insight of biochemists employing routine gel electrophoresis followed by Coomasie brilliant blue (CBB) staining.
8p trinhthamhodang5 16-05-2020 13 1 Download
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The X-ray structure of variant A of authentic boar salivary lipocalin (SAL), a pheromone-binding protein specifically expressed in the submaxillary glands of the boar, has been solvedandrefinedat 2.1 A ˚ resolution.The structuredisplays a classical lipocalin fold with a nine-stranded sandwiched bbarrel and anahelix.
8p research12 29-04-2013 35 1 Download
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To facilitate feeding, certain hematophagous invertebrates possess inhibi-tors of collagen-induced platelet aggregation in their saliva. However, their mechanisms of action have not been fully elucidated. Here, we describe two major salivary proteins, triplatin-1 and -2, from the assassin bug, Tria-toma infestans, which inhibited platelet aggregation induced by collagen but not by other agents including ADP, arachidonic acid, U46619 and thrombin.
8p inspiron33 25-03-2013 49 3 Download
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Triatoma infestans(Hemiptera: Reduviidae) is a hematophagous insect that transmits the protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas’ disease. Its saliva contains trialysin, a protein that forms pores in membranes. Peptides based on the N-terminus of trialysin lyse cells and fold into a-helical amphipathic segments resembling antimicrobial peptides. Using a specific antiserum against trialysin, we show here that trialysin is synthesized as a precursor that is less active than the protein released after saliva secretion. ...
9p media19 06-03-2013 45 1 Download
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Aegyptin is a 30 kDa mosquito salivary gland protein that binds to collagen and inhibits platelet aggregation. We have studied the biophysical properties of aegyptin and its mechanism of action. Light-scattering plot showed that aegyptin has an elongated monomeric form, which explains the apparent molecular mass of 110 kDa estimated by gel-filtration chromatography.
15p mobifone23 18-01-2013 29 3 Download
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Mumps is an acute, systemic, communicable viral infection whose most distinctive feature is swelling of one or both parotid glands. Involvement of other salivary glands, the meninges, the pancreas, and the gonads also is common. Etiologic Agent Mumps virus, a paramyxovirus, is pleomorphic and has a diameter ranging from 100 to 300 nm. The virion is composed of RNA and seven proteins. The RNA is surrounded by an envelope composed of glycoproteins, including a hemagglutinin-neuraminidase (HN), a hemolysis cell fusion antigen (F), and a matrix envelope protein (M).
6p crazy_sms 09-05-2012 49 4 Download
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Dengue viruses binding proteins from Aedes aegypti and Aedes polynesiensis salivary glands
4p dauphong5 25-12-2011 42 3 Download
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Salivary gland derived peptides as a new class of anti-inflammatory agents: review of preclinical pharmacology of C-terminal peptides of SMR1 protein...
11p thulanh27 12-12-2011 36 5 Download