Schiff base compounds
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The wave function regards like localized orbital locator, electron localized function, average localized ionization energy and non-covalent interaction are also examined as a means of theoretical evidence of the titled compound. The NBO calculations probe the intermolecular and intramolecular movement of charges, and additionally the molecule's stability. The ADMET properties are also considered for the compound with the assistance of Swiss ADMET online tool.
17p dianmotminh02 03-05-2024 1 1 Download
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In recent times many research activities have been carried out to prove the metal ion detection ability of Schiff bases. [13,14] In the present study, a new Schiff base has been synthesized from 5-bromo-2- hydroxybenzaldehyde and naphthalene-1,8-diamine and it is complexated with Co(II), Ni(II), Cu(II) and Zn(II) ions. The biological application of all the compounds has been analyzed and metal ions recognition property of the Schiff base has also been studied.
16p dianmotminh02 03-05-2024 5 1 Download
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In the present paper, the fluorescence sensor based on Schiff base and boric acid was developed for easy and rapid detection of L-tryptophan in different samples such as milk and bovine serum albumin. The photoluminescence intensity was measured by using fluorescent measurements and the results indicated that the developed fluorescent sensor was exhibited selective, sensitive, reliable determination against L-tryptophan, and a series of various analytes such as cations, amino acids, and organic compounds were used to investigate the selectivity of the fluorescent chemosensor.
13p lyhuyenthu 31-01-2023 2 2 Download
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In this study, the synthesis of dimeric disulfide-Schiff bases was carried out using two methods. The structures of the obtained Schiff bases were elucidated by various spectroscopic methods as well as elemental analysis. The Schiff base derivative compounds (3a-6) were screened for in vitro antibacterial activity against multidrug-resistant microorganisms using microdilution method. All the tested compounds showed varying inhibition zones against the pathogens.
22p lyhuyenthu 31-01-2023 9 2 Download
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In this study, Schiff bases of chitosan (CS) were synthesized using citronellal, citral, and their derivatives containing selenium and sulfur. Organoselenium and organosulfur compounds show attractive biological and pharmaceutical activities, which can be beneficial to CS-based materials.
11p vihermione 06-01-2023 4 2 Download
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The newly synthesized compounds were screened for their antimicrobial activities; some of them were found to be active towards the test microorganisms as the results demonstrated that the synthesized compounds exhibited a broad spectrum of activity with minimum inhibitory concentration (MIC) values of 31.3–500 µg/mL against gram-positive and gram-negative bacteria, Candia albicans and Saccharomyces cerevisiae.
12p langthannam 29-12-2021 9 0 Download
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A new anthracene derivative of calix[4]arene was synthesized as a highly fluorescent compound. This compound was examined for its fluorescent properties towards different metal ions (Li+, Na+, Mg2+, Ca2+, Ba2+, Ni2+, Cu2+, Zn2+, Pb2+) by UV and fluorescence spectroscopy. On complexation by alkaline earth metal cations and transition metal cations, the fluorescence spectrum was quenched. In particular, Ca2+ caused greater than 98% quenching of the anthracene derivative of calix[4]arene.
8p langthannam 29-12-2021 11 0 Download
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Comparison between the calculated and experimental results covering molecular structures, assignment of fundamental vibrational modes, and thermodynamic properties were investigated. The optimized molecular geometries were compared with the experimental data obtained from X-ray data of a similar complex, which indicated that the theoretical results agree with the corresponding experimental values. The UV-Vis spectrum of the compound was also recorded and some properties, such as HOMO and LUMO energies and λmax , were determined using DFT (PW91) method.
12p langthannam 29-12-2021 20 0 Download
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A series of dimeric unsymmetrical liquid crystals derived from heterocyclic 1,3-dimethylbarbituric acid exhibiting smectic A and nematic phase are reported. All compounds were prepared by the condensation of 4’-(R-(4- formylphenoxy)butoxy)biphenyl-4-carboxylate with 1,3-dimethylbarbituric acid in ethanol. The mesomorphic properties were investigated by DSC and POM, where the type of phase depends on the length of spacer alkoxy chains and the length of the terminal chain.
11p langthannam 29-12-2021 12 1 Download
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A number of novel N-acyl/aroyl-2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazides (4a–j) of biological interest were efficiently synthesized by treating 2-(5-phenyl-2H-tetrazole-2-yl)acetohydrazide (3) with a variety of aroyl/heterocyclyl or alkanoyl chlorides. FTIR, 1H NMR, 13C NMR, GC-MS, and elemental analyses data confirmed the structures assigned to the newly synthesized compounds.
7p langthannam 29-12-2021 13 0 Download
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All the complexes showed nonelectrolytic behavior. Moreover, the newly synthesized mixed ligand complexes were evaluated for their in vitro antimicrobial efficiency against bacteria and yeast. The compound named Co(L1 L) had good antifungal activity against Candida species, but no profound antibacterial effect against bacterial strains.
13p langthannam 29-12-2021 11 1 Download
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The newly synthesized compounds were characterized and confirmed by analytical and spectroscopic data (IR, MS, 1H NMR, and 13C NMR). Pyrazolo[1,5-a]pyrimidines 5a–c and 9a–c and Schiff bases 11b–f were investigated for their cytotoxicity against four human cancer cell lines (colon HCT116, lung A549, breast MCF-7, and liver HepG2) according to SRB assay and the structure–activity relationship was discussed.
12p langthannam 29-12-2021 14 0 Download
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Four new chiral Schiff base ligands (3a–4a, 3b–4b) have been prepared using aminoisopropylidene derivatives of glucose and aminochloralose derivatives of mannose. The synthesized compounds 1 and 2 were characterized by nuclear magnetic resonance ( 1 H and 13 C NMR), Fourier transform infrared spectroscopy (FTIR), UV/visible spectroscopy, and elemental analysis.
11p langthannam 29-12-2021 7 0 Download
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Novel compounds based on the 1,2,4-triazole skeleton were synthesized. A class of 4-amino-5-alkyl-4H-1,2,4-triazole-3- thione created by reaction of thiocarbohydrazide with long-chain aliphatic carboxylic acids, and then the Schiff bases were obtained in the media of heat and microwave waves, in the presence and the absence of a catalyst. Their chemical structures were assayed by elemental analysis, also device spectroscopic methods.
69p langthannam 29-12-2021 4 0 Download
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Coumarinyl 1,3,4-oxadiazoles were synthesized from Schiff bases and acetic anhydride. All compounds were characterized by melting points and their structures confirmed by mass and 1H and 13C NMR spectrometry. These novel coumarinyl derivatives were subjected to antibacterial, antifungal, antaflatoxigenic, and antioxidant activity. Their activity varied depending on their structure, where 2-(3-acetyl-5-(((4-methyl-2-oxo-2 H -chromen-7-yl)oxy)methyl)- 2,3-dihydro-1,3,4-oxadiazol-2-yl)-1,4-phenylene diacetate showed significant antioxidant and antibacterial activity on B. subtilis.
25p tudichquannguyet 29-11-2021 7 1 Download
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Synthesis of a new (E)-N1-((9-ethyl-9H-carbazol-3-yl)methylene)-5-nitrobenzene-1,2-diamine as a fluorescent chemosensor for selective detection of Fe3+ ion over a number of other metal ions is described. The method for the synthesis of the carbazole Schiff base was based on the condensation of carbazole-3-carbaldehyde with 4-nitro-ophenyldiamine in dimethylformamide in a moderate yield. The structure of the final compound was characterized by 1H NMR, 13C NMR, IR, mass spectrometry, and single crystal X-ray diffraction.
18p tudichquannguyet 29-11-2021 20 1 Download
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New Schiff bases were synthesized by condensation of methyl-5-(furan-2-yl)-5-oxopentanoate, methyl-4- (furan-2-yl)-4-oxobutanoate, methyl-5-(thiophene-2-yl)-5-oxopentanoate, and methyl-4-(thiophene-2-yl)-4-oxobutanoate with p-anisidine and n-butylamine. The structures of these synthesized compounds were clarified on the basis of elemental analysis, IR, 1H NMR, 13C NMR, and GC-MS spectroscopic techniques. In addition, antioxidant activity of the synthesized compounds was evaluated on the basis of DPPH radical.
28p tudichquannguyet 29-11-2021 17 1 Download
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In this study, a series of cyclotriphosphazene derivatives containing a Schiff base (3a–3d) were synthesized by the reactions of hexachlorocyclotriphosphazene (1) with bis-aryl Schiff bases (2a–2d) having different terminal groups (H, F, Cl, and Br). The products (3a–3d) were characterized by elemental and mass analyses, FT-IR, and 1 H, 13 C, and 31P NMR spectroscopies. Furthermore, the structure of compound 3a was also determined by X-ray crystallography.
17p tudichquannguyet 29-11-2021 10 1 Download
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New bis(isatins-thio/carbohydrazones) based on Schiff bases were prepared from terephthalaldehyde biscarbohydrazone and 5-substituted isatins in the presence of a drop of sulfuric acid under reflux in ethanol. Terephthalaldehyde bis(thio/carbohydrazone) was synthesized by the reaction of (thio)/carbohydrazide and terephthalaldehyde in the presence of a few drops of acetic acid under reflux in ethanol. The structures of these synthesized compounds were determined using IR, 1H NMR, and 13C NMR spectroscopy and elemental analysis.
20p tudichquannguyet 29-11-2021 14 1 Download
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Since benzo [b] thiophene scaffold is one of the privileged structures in drug discovery as this core exhibitsactivities for different biological problems, in this study bis (benzo[ b ]thiophene-2-yl) alkyl methanimine derivatives (1-9) were synthesized by reacting benzo[b]thiophene-2-carbaldehyde with diamines. All newly compounds were characterized by IR, 1H NMR and 13C NMR spectroscopic methods.
26p tudichquannguyet 29-11-2021 6 1 Download