Schiff’ bases adducts of gossypol

Gossypol, a yellow pigment, isolated from cotton seeds, exhibits many interesting biological activities: antitumor, antimalarial, anti-HIV [1]. But gossypol is toxic and this toxicity may be related to the two-functional aldehyde groups [2]. Many authors prepared the Schiff’s’ base adducts of gossypol from 1985 to 2002, but these authors did not pay attention to the factor that these adducts may present under or the imine form or the enamine one.

5p uocvong04 24-09-2015 37 5   Download