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Secreted peptide
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Ebook "The evolution of molecular biology: The search for the secrets of life" provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language that accommodates readers from a variety of backgrounds.
244p
lucchinguyen
28-12-2023
9
3
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Part 1 book "Metabolic and endocrine physiology" includes content: Endocrine system, endocrine secretory control, hormone disposition, measurement and secretion, mechanisms of catecholamine and polypeptide hormone action, steroid and thyroid hormones, hypothalamus and pituitary, proopiomelanocortin and related peptides,... and other contents.
110p
oursky07
24-10-2023
7
2
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It was examined whether undigested protein, namely resistant protein, affects glucagon-like peptide-1 (GLP-1) secretion in rats fed high amylose corn starch (HACS). Rats were fed one of three experimental diets for 28 d: casein without HACS, casein with HACS or dashigara with HACS.
8p
viisac
23-09-2023
5
1
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Patients with long QT syndrome due to rare loss-of-function mutations in the human ether-á-go-gorelated gene (hERG) have prolonged QT interval, risk of arrhythmias, increased secretion of insulin and incretins and impaired glucagon response to hypoglycemia.
9p
vinarcissa
21-03-2023
3
1
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As in animals, cell–cell communication plays a pivotal role in male–female recognition during plant sexual reproduction. Prelaid peptides secreted from the female reproductive tissues guide pollen tubes towards ovules for fertilization. However, the elaborate mechanisms for this dialogue have remained elusive, particularly from the male perspective.
29p
viaristotle
29-01-2022
10
0
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Antimicrobial resistance (AMR) is a significant threat to human health globally. Diseases caused by AMR are getting more challenging to cure due to the increasing rate of resistance of microbial pathogens. Drugs formulated with antimicrobial peptide (AMP) can be applied to treat these diseases. AMPs are found naturally within organisms, especially amphibians, and is related to the high adaptability of defence mechanisms against various pathogens and predators in the environment.
12p
dolomite36
30-12-2021
8
0
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The purpose of the study was to measure the secretion levels of recombinant glucoamylase from Pichia pastoris, by using the α-mating factor secretion signal peptide (α-MF) and the native signal peptide of glucoamylase from Aspergillus flavus NSH9. The Aspergillus flavus NSH9 gene (with and without native signal sequences), encoding a pH and thermostable glucoamylase with an SBD, was successfully cloned and expressed in Pichia pastoris to produce recombinant glucoamylases.
4p
mudbound
10-12-2021
11
1
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Antimicrobial peptides (AMPs) are multifunctional effector molecules that often combine direct antimicrobial activities with signaling or immunomodulatory functions. The skin secretions of anurans contain a variety of such bioactive peptides. The identification of AMPs from frog species often requires sacrificing several specimens to obtain small quantities of crude peptides, followed by activity based fractionation to identify the active principles.
10p
vitzuyu2711
29-09-2021
8
1
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Many small peptides regulate eukaryotic cell biology. In fungi, some of these peptides are produced after KEX2 protease activity on proteins displaying repetitions of identical or nearly identical motifs. Following this endoprotease activity, peptides are released in the extracellular space.
15p
vigiselle2711
30-08-2021
5
1
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Chemoresistance is one of the main problems in treatment of cancer. Periostin (PN) is a stromal protein which is mostly secreted from cancer associated fibroblasts in the tumor microenvironment and can promote cancer progression including cell survival, metastasis, and chemoresistance.
16p
vianrose2711
27-04-2021
13
2
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Light, tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted peptide of the TNF superfamily. It binds to the herpesvirus entry mediator (HVEM). Light/HVEM signaling is well reported as an important factor linking inflammation and obesity.
6p
tamynhan5
10-12-2020
14
2
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Human Hematopoietic Signal peptide-containing Secreted 1 (hHSS1) is a truly novel protein, defining a new class of secreted factors. We have previously reported that ectopic overexpression of hHSS1 has a negative modulatory effect on cell proliferation and tumorigenesis in glioblastoma model systems.
17p
vilisa271
22-09-2020
13
1
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Luteinizing hormone-releasing hormone receptor (LHRHr) represents a promising therapeutic target for treating sex hormone-dependent tumors. We coupled cecropin B, an antimicrobial peptide, to LHRH’, a form of LHRH modified at carboxyl-terminal residues 4–10, which binds to LHRHr without interfering with luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion.
9p
vinaypyidaw2711
26-08-2020
12
1
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Gastrointestinal tract function and it’s integrity are controlled by a number of peptides whose secretion is influenced by severe inflammation. In stomach the main regulatory peptide is ghrelin.
9p
viorochimaru2711
30-05-2020
7
1
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The therapeutic use of α-amidated peptides (e.g. calcitonin, glucagon-like peptide) has increased dramatically, but there are major impediments to wider use of such peptides. Larger peptides are expensive to synthesize, and short plasma half-lives frequently limit the clinical circumstances in which the peptides would be useful.
13p
viuchiha2711
21-04-2020
14
0
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Site-specific integration system allows foreign DNA to be integrated into the specific site of the host genome, enabling stable expression of heterologous protein. In this study, integrative vectors for secretion and surface display of proteins were constructed based on a lactococcal phage TP901–1 integrating system.
12p
vihamax2711
21-04-2020
14
1
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The R-Spondin proteins comprise a family of secreted proteins, known for their important roles in cell proliferation, differentiation and death, by inducing the Wnt pathway. Several studies have demonstrated the importance of RSPOs in regulation of a number of tissue-specific processes, namely: bone formation, skeletal muscle tissue development, proliferation of pancreatic β-cells and intestinal stem cells and even cancer.
14p
vihamax2711
21-04-2020
17
1
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Antifungal activity of lactic acid bacteria in food preservation is one of the technological properties sought. The antifungal effect of lactic acid bacteria has been studied. Four strains namely Lactobacillus plantarum G100, Lactobacillus brevis L62, Lactobacillus rhamnosus THT and Pediococcus pentosaceus Hela showed inhibitory activity against Tricoderma F14, Penicillium canescens 10-10 C, Aspergillus niger and Rhyzopus stoloniferous. Antifungal activity of L. rhamnosus THT strain depended mostly on the presence of these organic acids. L. brevis L62 and P.
12p
chauchaungayxua1
04-12-2019
21
1
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Proton pump inhibitor (PPI) use was reportedly associated with an excess of adverse cardiovascular (CV) events, thus making their systemic effects relevant to public health. PPIs reduce gastric acid secretion, causing increased gastrin release.
7p
vicaracas2711
27-11-2019
11
0
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Diabetes mellitus is a chronic disease in which the pancreas no longer produces enough insulin. Pancreatic alpha cell mass increases in response to insufficient insulin secretion. However, the reason for this increase is not clear.
7p
vinasaki2711
12-11-2019
10
0
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