![](images/graphics/blank.gif)
Sequence alignment probability
-
Read alignment is the first step in most sequencing data analyses. Because a read’s point of origin can be ambiguous, aligners report a mapping quality, which is the probability that the reported alignment is incorrect. Despite its importance, there is no established and general method for calculating mapping quality.
12p
vialfrednobel
29-01-2022
12
0
Download
-
Reconstruction of multiple sequence alignments (MSAs) is a crucial step in most homology-based sequence analyses, which constitute an integral part of computational biology. To improve the accuracy of this crucial step, it is essential to better characterize errors that state-of-the-art aligners typically make.
19p
vioklahoma2711
19-11-2020
11
4
Download
-
Insertions and deletions (indels) account for more nucleotide differences between two related DNA sequences than substitutions do, and thus it is imperative to develop a method to reliably calculate the occurrence probabilities of sequence alignments via evolutionary processes on an entire sequence.
21p
vioklahoma2711
19-11-2020
18
2
Download
-
This paper presents a translation model that is based on tree sequence alignment, where a tree sequence refers to a single sequence of subtrees that covers a phrase. The model leverages on the strengths of both phrase-based and linguistically syntax-based method. It automatically learns aligned tree sequence pairs with mapping probabilities from word-aligned biparsed parallel texts.
9p
hongphan_1
15-04-2013
42
2
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)