Serum predictors

Hepatic proteins, including albumin, prealbumin, and transferrin have been confirmed to be prognostic predictors in various cancers. This study aimed to comprehensively assess the prognostic value of these three serum markers in patients with cancer cachexia.

12p vikoch 27-06-2024 1 1   Download

To improve the prognosis of patients with metastatic colorectal cancer (mCRC), investigating predictive biomarkers of their prognosis and chemotherapeutic responsiveness is necessary. This study aimed to analyze the clinical significance of serum proteinase-3 (PRTN3) as a predictor for prognosis and chemosensitivity, especially to bevacizumab therapy, in mCRC.

15p vikoch 27-06-2024 1 1   Download

Humoral immune responses to infectious agents or vaccination vary substantially among individuals, and many of the factors responsible for this variability remain to be defined. Current evidence suggests that human genetic variation influences (i) serum immunoglobulin levels, (ii) seroconversion rates, and (iii) intensity of antigenspecific immune responses.

13p vibransone 28-03-2024 4 2   Download

There is no consensus on the role of serum dehydroepiandrosterone (DHEA) concentrations in the detection of prostate cancer. This study examined the efectiveness of serum DHEA in predicting candidate patients for active surveillance (AS) prior to prostate biopsy.

9p vileonardodavinci 23-12-2023 3 2   Download

To describe pattern of multi-organ failure and predictive factors of mortality in septic shock patients with multi-organ failure treated at 108 Military Central Hospital. Subject and method: A prospective cross-sectional study was conducted on 98 septic shock patients with multi-organ failure in 108 Military Central Hospital from 2017 to 2018.

6p visoros 01-11-2023 5 1   Download

The systemic inflammation score (SIS), based on serum albumin (Alb) and lymphocyte-to-monocyte ratio (LMR), is a novel prognostic tool for some tumours. Studies indicate that the SIS can be used as a postoperative prognostic marker. However, its predictive value in elderly oesophageal squamous cell carcinoma (ESCC) patients treated with radiotherapy is unclear.

11p visharma 20-10-2023 2 2   Download

Neuroblastoma (NB) is a childhood malignant tumor,50% of high-risk NB children still have recurrence, and the long-term survival rate is very low. NB tumors expressing high levels of BDNF/TrkB are associated with poor survival outcomes.In this study, we show that the trends of serum concentration of BDNF at different growth stages after birth, and explore the relationship with NB replase.

9p vioracle 29-09-2023 3 2   Download

Serum chloride (Cl−) is one of the most essential extracellular anions. Based on emerging evidence obtained from patients with kidney or heart disease, hypochloremia has been recognized as an independent predictor of mortality. Nevertheless, excessive Cl− can also cause death in severely ill patients.

8p viisaacnewton 26-04-2022 15 1   Download

The ratio of serum apolipoprotein B (apoB) to apolipoprotein A-I (apoAI) had been reported as a prog‑ nostic factor in colorectal cancer. This retrospective study aimed to assess the implication of apoB-to-apoAI ratio in predicting liver metastasis from rectal cancer (RC).

8p vielonmusk 21-01-2022 13 0   Download

This study aims to evaluate the role of the fibrinogen/albumin ratio (FAR) in predicting platinum resistance and survival outcomes of patients with ovarian clear cell carcinoma (OCCC). Methods: Coagulation function and D-dimer, serum albumin, CA125 and HE4 levels were measured before surgery in OCCC patients undergoing initial surgery in our institution.

10p vielonmusk 21-01-2022 16 1   Download

Cardiac hypertrophy (CH), leading to cardiac failure is due to chronic metabolic alterations occurring during cellular stress. Besides the already known relationship between oxidative stress and CH, there are implications of reductive stress leading to CH. This study attempted to develop reductive stress-based CH rat model using n-acetyl-L-cysteine (NAC), a glutathione agonist that was compared with typical isoproterenol (ISO) induced CH model.

21p thiencuuchu 27-11-2021 11 1   Download

Increased serum urate levels are associated with poor outcomes including but not limited to gout. It is unclear whether serum urate levels are the sole predictor of incident hyperuricemia or whether demographic and clinical risk factors also predict the development of hyperuricemia.

8p viannito2711 20-04-2021 9 1   Download

Previous studies have shown that serum uric acid (UA) levels are correlated with the severity of idiopathic pulmonary arterial hypertension (IPAH) and are predictors of disease prognosis. Still, few studies have explored the value of serum UA in pulmonary arterial hypertension secondary to connective tissue disease (CTDPAH). This retrospective study aimed to investigate the clinical value of serum UA levels in patients with CTD-PAH.

9p vimichigan2711 26-03-2021 8 1   Download

The aim of the present study is to evaluate serum osteoprotegerin (OPG) and soluble receptor activator of nuclear factor κB ligand (sRANKL) levels in a randomly selected male cohort over 50 years of age and its association with cystatin C.

7p vioregon2711 22-02-2021 12 2   Download

The treatment strategy for evolutive septic arthritis (SA) with coexistent degenerative joint disease is not well established.

10p vivermont2711 28-01-2021 13 1   Download

Candidate predictive biomarkers for epidermal growth factor receptor inhibitors (EGFRi), skin rash and serum proteomic assays, require further qualification to improve EGFRi therapy in non-small cell lung cancer (NSCLC).

10p vijennie2711 25-09-2020 16 1   Download

Recently, the endothelial Activation and Stress Index (EASIX) score has been reported to predict overall survival (OS) after allogeneic stem cell transplantation. This study evaluated the prognostic role of EASIX score in patients with newly diagnosed multiple myeloma (MM).

10p vimoscow2711 29-08-2020 6 1   Download

Serum carcinoembryonic antigen (CEA) levels are a predictor of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) efficacy and are associated with epidermal growth factor receptor (EGFR) gene mutations.

7p vidhaka2711 31-07-2020 10 1   Download

An ideal tumor marker should be capable of being detected at any stage of the disease. However, gastric cancer patients do not always have elevated serum carcinoembryonic antigen (CEA) levels, even in advanced cases.

11p vibaku2711 22-07-2020 11 2   Download

Breast cancer is one of the most public and fatal malignancy worldwide. One of the main cytokines playing a role in breast cancer progression is TGF1. In this study we aimed to determine the clinical significance of the serum TGFβ1 levels in breast cancer patients by comparing the levels of TGFβ1 in breast cancer patients and in control females, assessment of the levels of TGFβ1 in diagnosed breast cancer patients before and after treatment and correlating between the levels of TGFβ1 in breast cancer patients with the laboratory and radiological findings.

12p angicungduoc6 22-07-2020 21 0   Download