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Several metabolites
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Interactions between the gut microbiota, diet, and host metabolism contribute to the development of cardiovascular disease, but a firm link between disease-specific gut microbiota alterations and circulating metabolites is lacking.
12p
vicwell
29-02-2024
9
1
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Ebook "Phytochemicals, plant growth, and the environment (Phytochemicals, plant growth, and the environment, Volume 42)" includes a total of seven articles, many, but not all, based on talks presented at the 50th annual meeting of the PSNA. As was seen in RAP volume 41, These seven Perspectives give a very good picture of the breadth of plant (bio)chemistry research in North America, which is also indicative of the state of the field worldwide.
179p
manmanthanhla0201
26-02-2024
1
1
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Several generic products containing simvastatin are circulating on the Vietnamese market at a more inexpensive price than that of a brand-name one. These formulations, however, have not been assessed for in vivo bioequivalence to the reference product.
9p
vikissinger
21-12-2023
2
1
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The aerial parts of Artemisia absinthium and Artemisia vulgaris are used in infusions for the treatment of several diseases. Besides secondary metabolites, carbohydrates are also extracted with hot water and are present in the infusions. The plant carbohydrates exhibit several of therapeutic properties and their biological functions are related to chemical structure.
8p
vihermione
06-01-2023
10
2
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Recent advances in metabolomics have enabled larger proportions of the human metabolome to be analyzed quantitatively. However, this usually requires the use of several chromatographic methods coupled to mass spectrometry to cover the wide range of polarity, acidity/basicity and concentration of metabolites.
11p
viginny
23-12-2022
10
4
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Although several novel resistant breast cancer cell lines have been established, only a few resistant breast cancer cell lines overexpress breast cancer resistance proteins (BCRP). The aim of this study was to establish new resistant breast cancer cell lines overexpressing BCRP using SN38 (7-ethyl-10-hydroxycamptothecin), an active metabolite of irinotecan and was to discover genes and mechanisms associated with multidrug resistance.
14p
vikolindagrabar
27-07-2022
5
1
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Considering the high incidence of equine asthma (> 14%) within horse population and the importance of this animal model for human disease, we aimed to investigate the metabolomic profile of bronchoalveolar lavage fluid (BALF) and exhaled breath condensate (EBC) in healthy and asthmatic horses.
9p
vigandhi
23-02-2022
14
1
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Curculigo orchioides and Curculigo latifolia (Hypoxidaceae) have been widely used as traditional medicines in Indonesia and other Asian countries for antihyperglycemic, aphrodisiac, antioxidant, and antimicrobial treatments. This work aimed to determine the distribution of secretory structures and metabolites. Metabolite profiling approach of the plant organs was determined by UHPLC-QOrbitrap-HRMS.
32p
tudichquannguyet
29-11-2021
11
1
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Tumor cells exhibit enhanced metabolism of nutrients to satisfy the demand of sustained proliferation in vivo. Seminal reports have presented evidence that tryptophan (Trp) metabolic reprogramming induced by aberrant indoleamine 2,3-dioxygenases could promote tumor development in several cancer types. However, the underlying mechanism of Trp metabolism associated tumor progression is not fully understood.
11p
vimahuateng
26-11-2021
8
1
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Black Aspergilli represent one of the most important fungal resources of primary and secondary metabolites for biotechnological industry. Having several black Aspergilli sequenced genomes should allow targeting the production of certain metabolites with bioactive properties.
16p
vibeauty
23-10-2021
14
1
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RNAseq against total RNA from RD and SD cultivars found several phenylpropanoid genes, metabolite transporter genes and genes involved in gene regulation or modification to be differentially expressed between CDC Pintium and 1533–15.
13p
vibeauty
23-10-2021
12
0
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Soybean cyst nematode, Heterodera glycines, is one of the most devastating pathogens of soybean and causes severe annual yield losses worldwide. Different soybean varieties exhibit different responses to H. glycines infection at various levels, such as the genomic, transcriptional, proteomic and metabolomic levels.
17p
vijichea2711
28-05-2021
7
1
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Fusarium oxysporum f. sp. niveum (FON) causes Fusarium wilt in watermelon. Several disease-resistant watermelon varieties have been developed to combat Fusarium wilt. However, the key metabolites that mount defense responses in these watermelon varieties are unknown.
12p
vijichea2711
28-05-2021
33
1
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Seven compounds were isolated and characterized from the culture broth of the marine bacteria Nocardiopsis sp. (strain G057), which was isolated from sediment collecting at Cô Tô – Quảng Ninh. Their structures were determined by spectroscopic analysis including MS and 2D NMR, as well as by comparison with reported data in the literature. All compounds were evaluated for their antimicrobial activity against a panel of clinically significant microorganisms. Compounds 1, 2 and 7 selectively inhibited Escherichia coli with a MIC value of 32, 64, 8 μg/mL, respectively.
5p
cothumenhmong11
10-05-2021
8
1
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The objectives of the thesis: Study on chemical constituents of three Antidesma species including A. acidum, A. ghaesembilla, and A. hainanensis growing in Vietnam; evaluation of biological activities of isolated metabolites to find potential compounds.
27p
capheviahe27
23-02-2021
26
4
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In this study, we evaluated chemical responses of K. obovata and S. caseolaris through comparisons of the content of metabolites and element ions in leaves of mangrove plants located under different ecological conditions in the Red River delta. In the low salinity area (Thuy Truong), specific leaf areas of K. obovata and S. caseolaris were much lower while the succulent index was higher compared to those in the high salinity area (Kim Trung).
13p
nguaconbaynhay10
20-02-2021
9
2
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The circadian clock is a critical regulator of biological functions controlling behavioral, physiological and biochemical processes. Because the liver is the primary regulator of metabolites within the mammalian body and the disruption of circadian rhythms in liver is associated with severe illness, circadian regulators would play a strong role in maintaining liver function.
14p
vikentucky2711
26-11-2020
10
1
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Identification of individual components in complex mixtures is an important and sometimes daunting task in several research areas like metabolomics and natural product studies. NMR spectroscopy is an excellent technique for analysis of mixtures of organic compounds and gives a detailed chemical fingerprint of most individual components above the detection limit.
8p
vikentucky2711
26-11-2020
12
1
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Glyoxalase 1 is a key enzyme in the detoxification of reactive metabolites such as methylglyoxal and induced Glyoxalase 1 expression has been demonstrated for several human malignancies.
9p
vidhaka2711
31-07-2020
7
2
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Antidesma bunius known as ‘currant tree’ is a popular fruit in several Asian countries. During our exploration of wild fruits of Manipur, India, we identified this edible fruit growing naturally in their wild habitat. An exhaustive biochemical analyses revealed very high concentration of mineral contents relative to other well known fruits. Correlation analysis showed significant relationship between ascorbic acid content and antioxidant oxidant activity.
12p
kethamoi6
29-06-2020
11
2
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