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Significant biological processes
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Professional teaching competence is significantly influenced by beliefs about teaching and learning. Prospective teachers start their teacher training with quite persistent beliefs about learning processes. The present study investigated how prospective teachers remembered their previous biology lessons as well as how they imagine the lessons they will conduct in the future.
13p
viarnault
25-04-2024
1
1
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The growth factor receptor network (GFRN) plays a significant role in driving key oncogenic processes. However, assessment of global GFRN activity is challenging due to complex crosstalk among GFRN components, or pathways, and the inability to study complex signaling networks in patient tumors.
19p
vioraclene
31-03-2024
3
2
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Ebook "MicroRNA detection and pathological functions" summarizes microRNA (miRNA) biology in a variety of pathological processes, emphasizing the significant potential applications of miRNA in diagnostics and prognostics, as well as novel drug targets. The conventional techniques used for miRNA detection including standard PCR, Northern blotting, microarray and clone methods are addressed.
108p
nhanphanguyet
28-01-2024
3
2
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Ebook "Agrobacterium: From biology to biotechnology" continues with a description of how Agrobacterium is used as a tool in plant biotechnology. The next two chapters describe our knowledge of the Agrobacterium genome gained with the advent of genomics approaches and place Agrobacterium in the taxonomic context of related bacterial species. The main portion of the book, which comprises 11 chapters, provides a detailed review of virtually all molecular aspects of the genetic transformation process, including chemistry, biochemistry and molecular biology of host recognition and attachment,...
768p
tachieuhoa
28-01-2024
6
2
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Ebook "Asking questions in biology: A guide to hypothesis testing, experimental design and presentation in practical work and research projects" to introduce students in the biological sciences to the skills of observation and enquiry, but focusing on the process of enquiry – how to formulate hypotheses and predictions from raw information, how to design critical observations and experiments, and how to choose appropriate analyses – rather than on laboratory, field and analytical techniques perse.
263p
lucchinguyen
28-12-2023
5
3
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Molecule interacting with CasL 1 (MICAL1), a multidomain flavoprotein monooxygenase, is strongly involved in the biological processes related to cancer cell proliferation and metastasis. However, there were few reports on the clinical significance of MICAL1 in renal clear cell carcinoma.
15p
vileonardodavinci
23-12-2023
3
2
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Obesity is heritable. It predisposes to many diseases. The objectives of this study were to create a compendium of genes relevant to feeding behavior (FB) and/or body weight (BW) regulation; to construct and to analyze networks formed by associations between genes/proteins; and to identify the most significant genes, biological processes/pathways, and tissues/organs involved in BW regulation.
28p
vinarcissa
21-03-2023
4
1
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Pancreatic cancer (PC) is a highly lethal disease and an increasing cause of cancer-associated mortality worldwide. Interferon regulatory factors (IRFs) play vital roles in immune response and tumor cellular biological processes.
11p
vihagrid
30-01-2023
9
4
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The mutational processes underlying non-coding cancer mutations and their biological significance in tumor evolution are poorly understood. To get better insights into the biological mechanisms of mutational processes in breast cancer, we integrate whole-genome level somatic mutations from breast cancer patients with chromatin states and transcription factor binding events.
15p
vigalileogalilei
27-02-2022
24
2
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Structural variations (SVs) account for about 1% of the differences among human genomes and play a significant role in phenotypic variation and disease susceptibility. The emerging nanopore sequencing technology can generate long sequence reads and can potentially provide accurate SV identification.
13p
vielonmusk
30-01-2022
10
0
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A-to-I RNA editing is an important step in RNA processing in which specific adenosines in some RNA molecules are post-transcriptionally modified to inosines. RNA editing has emerged as a widespread mechanism for generating transcriptome diversity. However, there remain significant knowledge gaps about the variation and function of RNA editing.
15p
vialfrednobel
29-01-2022
11
0
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: It has been a long time since researchers have focused on the cytoskeletal proteins’ unconventional functions in the nucleus. Subcellular localization of a protein not only affects its functions but also determines the accessibility for cellular processes. Desmin is a muscle-specific, cytoplasmic intermediate filament protein, the cytoplasmic roles of which are defined. Yet, there is some evidence pointing out nuclear functions for desmin. In silico and wet lab analysis shows that desmin can enter and function in the nucleus.
9p
langthannam
29-12-2021
10
0
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An efficient, convenient, and environmentally benign procedure for the synthesis of novel benzo[a]chromeno[2,3-c]phenazine derivatives has been developed by domino four-component condensation reaction between 2-hydroxynaphthalene-1,4-dione, o−phenylenediamine, aromatic aldehydes, and naphthols or phenol in the presence of a catalytic amount of DABCO as an expedient, ecofriendly, and reusable base catalyst under microwave irradiation in EtOH/H2O (1:1).
10p
tudichquannguyet
29-11-2021
13
1
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Hepatocellular carcinoma (HCC) is one of the deadliest cancers. Research on HCC so far primarily focused on genes and provided limited information on genomic repeats, which constitute more than half of the human genome and contribute to genomic stability. In line with this, repeat dysregulation was significantly shown to be pathological in various cancers and other diseases. In this study, we aimed to determine the full repeat expression profile of HCC for the first time.
14p
thiencuuchu
27-11-2021
21
3
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The osteogenic differentiation markers BMP2, BMP4, COL1A1, OPN, OCN and PF4 evaluated using RT-PCR. The tumor dimensions in the hMSCs group were significantly higher than those of the remaining groups (p < 0.01). The number of metastatic foci in the BMP2+hMSCs group was significantly lower than those of the other groups (p < 0.01). The current results showed that the intraperitoneal route could be efficiently used for targeting hMSCs to the tumoral tissues for effective BMP2 delivery.
13p
thiencuuchu
27-11-2021
14
1
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Next-generation sequencing (NGS) has revolutionized almost all fields of biology, agriculture and medicine, and is widely utilized to analyse genetic variation. Over the past decade, the NGS pipeline has been steadily improved, and the entire process is currently relatively straightforward. However, NGS instrumentation still requires upfront library preparation, which can be a laborious process, requiring significant hands-on time.
6p
vibeauty
23-10-2021
11
0
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Genome wide association studies (GWAS) have helped identify large numbers of genetic loci that significantly associate with increased risk of developing diseases. However, translating genetic knowledge into understanding of the molecular mechanisms underpinning disease (i.e. disease-specific impacted biological processes) has to date proved to be a major challenge. This is primarily due to difficulties in confidently defining candidate genes at GWAS-risk loci.
8p
vibeauty
23-10-2021
5
0
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The parasite Varroa destructor represents a significant threat to honeybee colonies. Indeed, development of Varroa infestation within colonies, if left untreated, often leads to the death of the colony. Although its impact on bees has been extensively studied, less is known about its biology and the functional processes governing its adult life cycle and adaptation to its host.
19p
vibeauty
23-10-2021
4
1
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Histone modifications play a significant role in the regulation of transcription and various biological processes, such as development and regeneration. Though a few genomic (including DNA methylation patterns) and transcriptomic studies are currently available in switchgrass, the genome-wide distribution of histone modifications has not yet been studied to help elucidate gene regulation and its application to switchgrass improvement.
15p
visilicon2711
20-08-2021
13
1
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K-mer-based methods have greatly advanced in recent years, largely driven by the realization of their biological significance and by the advent of next-generation sequencing. Their speed and their independence from the annotation process are major advantages.
22p
vilichoo2711
23-06-2021
17
1
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