Significant contributor
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Long non-coding RNA (lncRNA) H19 has gained significant recognition as a pivotal contributor to the initiation and advancement of gynecologic cancers, encompassing ovarian, endometrial, cervical, and breast cancers. H19 exhibits a complex array of mechanisms, demonstrating dualistic effects on tumorigenesis as it can function as both an oncogene and a tumor suppressor, contingent upon the specific context and type of cancer being investigated.
14p vishanshan 27-06-2024 2 1 Download
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The swine farming has a significant potential for biogas emissions and is a substantial contributor to greenhouse gas emissions within Vietnam's agricultural sector. This study was conducted to determine the total amount of CH4, and CO2 (eq) released from mature management activities and emission coefficients of CH4 and CO2 (eq) at different swine farms in Northern, Central and Southern regions, using tier 1 and tier 2 according to IPCC method.
8p visergeyne 18-06-2024 11 0 Download
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With the emerging trends in supply chain management, this research aims in providing the effect of supply chain contributors including partnership, collaboration and integration on financial performance of SMEs in Thailand. It also examine the mediation impact of supply chain performance between these strategies and overall financial performance of these firms. Questionnaires were designed to obtain required information from the manager, representatives and key members of SMEs in Thailand. The sample size selected is 334. The collected information is analyzed using SPSS and AMOS.
10p longtimenosee10 26-04-2024 2 1 Download
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The fishery sector is one of the main contributors to the economic growth of the region. It plays a significant role in sustainable livelihoods and poverty reduction in several households and communities. The purpose of this study is to investigate the supply chain strategy for developing fishery industry in Aceh province and examine the mediating role of competitive advantage in the relationship between service quality and fishery industry performance, Indonesia.
11p longtimenosee07 29-03-2024 3 2 Download
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Air pollution is one of the leading risk factors for death but also a significant contributor to the global disease burden, affecting quality of life. According to a World Health Organisation (WHO) report, seven million people die from air pollution every year, and 9 out of 10 people worldwide breathe polluted air. Any person can be affected by exposure to polluted air, especially the elderly, children, pregnant women, and people with comorbidities.
9p viellison 28-03-2024 2 1 Download
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Lung cancer is one of the most lethal tumors with a poor survival rate even in those patients receiving new therapies. Metabolism is considered one of the hallmarks in carcinogenesis and lipid metabolism is emerging as a significant contributor to tumor metabolic reprogramming. We previously described a profile of some lipid metabolism related genes with potential prognostic value in advanced lung cancer.
10p vileonardodavinci 23-12-2023 2 2 Download
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Mercury (Hg) is a global pollutant that has gained monumental attention in recent decades due to its neurotoxicity and great bioaccumulation features. The atmosphere plays a key role in the movement of Hg in the environment, and residential combustion is a significant contributor to atmospheric Hg.
9p viwhitewolf 11-07-2023 6 3 Download
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Mycoplasma bovis causes mastitis, otitis, pneumonia and arthritis in cattle and is a major contributor to bovine respiratory disease complex. Around the year 2000, it emerged as a significant threat to the health of North American bison. Whether healthy bison are carriers of M. bovis and when they were first exposed is not known.
10p vigandhi 23-02-2022 13 1 Download
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The designed catalyst has shown an enzyme-like kinetics profile with a significant substrate affinity. The cooperative action in between catalytic triad amino acids has shown improved catalytic activity in comparison to only the histidine-containing control group. Histidine is an irreplaceable contributor to catalytic action and this is an additional reason for control group selection. This new method based on the self-assembly of covalently conjugated action units offers a new platform for enzyme investigations and their further applications.
9p tudichquannguyet 29-11-2021 8 1 Download
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Pacu (Piaractus mesopotamicus) is one of the most important Neotropical aquaculture species from South America. Disease outbreaks caused by Aeromonas hydrophila infection have been considered significant contributors to the declining levels of pacu production.
13p vijeeni2711 30-06-2021 14 2 Download
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A resource model of extension as suggested by Salmon (1980), puts farmers and researchers as equally important contributors. The function of the extension is to transfer and nurture this pool of knowledge within the rural system. The concept of leadership has undergone considerable change as research in this area of study progressed.
10p trinhthamhodang11 27-04-2021 10 1 Download
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Carpal tunnel syndrome (CTS) is the most common neuropathy of the upper limb and a significant contributor to hand functional impairment and disability. Effective treatment options include conservative and surgical interventions, however it is not possible at present to predict the outcome of treatment.
7p viannito2711 20-04-2021 21 2 Download
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Low back pain (LBP) and knee osteoarthritis (OA) are major contributors to disability worldwide. These conditions result in a significant burden at both individual and societal levels. Engagement in regular physical activity and exercise programs are known to improve physical function in both chronic LBP and knee OA populations.
11p vivermont2711 28-01-2021 6 2 Download
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Advanced glycation end products (AGEs) and their receptor RAGE emerge as important pathogenic contributors in colorectal carcinogenesis. However, their relationship to the detoxification enzyme Glyoxalase (GLO)-I and Adiponectin receptors (AdipoR1, AdipoR2) in colorectal carcinoma (CRC) is currently understudied.
14p vinaypyidaw2711 26-08-2020 11 2 Download
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Epigenetic alterations have been recognized as important contributors to the pathogenesis of PDAC. However, the role of histone variants in pancreatic tumor progression is still not completely understood. The aim of this study was to explore the expression and prognostic significance of histone protein variants in PDAC patients.
9p vimanama2711 30-07-2020 11 2 Download
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Prostate cancer is a major contributor to mortality worldwide, and significant efforts are being undertaken to decipher specific cellular and molecular pathways underlying the disease.
10p vimanama2711 30-07-2020 14 2 Download
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This article presents an editorial perspective on the challenges associated with e-mail management for academic physicians. We include 2-week analysis of our own e-mails as illustrations of the e-mail volume and content. We discuss the contributors to high e-mail volumes, focusing especially on unsolicited e-mails from medical/scientific conferences and open-access journals (sometimes termed “academic spam emails”), as these e-mails comprise a significant volume and are targeted to physicians and scientists.
8p caothientrangnguyen 10-05-2020 19 0 Download
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Agriculture is one of the significant contributors to the Indian economy. Growing a good crop depends on multiple factors like soil condition, climatic condition, rainfall, selection of good variety etc. and selection of crop plays a very important role in getting a good return. India has a unique position as a major supplier of seed spices in the international trade. Some major seed spices are Cumin, Coriander, Fennel and Fenugreek and minor seed spices are Ajwain, Nigella, Aniseed, Dill, Caraway, and Celery.
10p caygaocaolon4 04-04-2020 21 2 Download
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Cerebral palsy is the most common cause of physical disability in childhood. Spasticity is a significant contributor to the secondary impairments impacting functional performance and participation.
13p vinatri2711 29-02-2020 14 0 Download
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Livestock sector plays important role in Indian economy. The dairy industry can go a long way in augmenting the income of the farmers. The present paper focuses on the factors affecting farm income. The study was conducted in the two agroclimatic zones of Punjab state i.e. kandi and plain zone. From each zone two districts, one block from each district and further three villages from each block and fifteen farmers from each village were selected randomly. The data was collected with personal interview method. The annual income realized by farmers varied a lot in both the regions.
6p caygaocaolon3 27-02-2020 22 0 Download