Simulated microgravity

Microgravity has been shown to markedly affect reproduction in humans and animals, especially reproductive organs such as the ovaries. Granulosa cells are one of the important components of the ovary, playing an important role in supporting oocyte maturation and fertilization. However, the effects of microgravity on granulosa cells have not been well characterized.

7p vimulcahy 18-09-2023 5 2   Download

This study aimed to assess the effects of simulated microgravity (SMG) on senescent human fibroblasts (HFs). The HFs were treated with 150 µM H2O2 in a culture medium for 90 minutes for senescent induction. The senescent HFs were induced SMG for 72 hours by a Gravity simulator, while the control group was treated in the same CO2 incubator.

8p vicaptainmarvel 21-04-2023 5 2   Download

This study aimed to estimate the effects of simulated microgravity (SMG) on mesenchymal stem cells (MSCs). The 3D clinostat was applied to induce to simulated microgravity on MSC. The results showed that the MSC density in control group was higher than the SMG group. The cell cycle analysis demonstrated that the MSC ratio in G0/G1 phase in SMG group was higher than that of the control group, while the MSC ratio in S phase and G2/M phase in SMG group was lower than those of the control group.

8p spiritedaway36 25-11-2021 10 0   Download

The aim of this thesis was to gain an understanding of how the simulated microgravity condition affects the development of hucMSC by investigating the changes in cell morphology, proliferation and cytoskeleton structure of hucMSCs under in vitro condition.

27p beloveinhouse01 15-08-2021 16 4   Download

The present study investigated how mouse fibroblasts changed under microgravity (SMG) conditions (< 10-3 G) simulated by 3D clinostat. Results showed that SMG condition markedly reduced the proliferation of mouse fibroblasts, significantly reducing the nuclear area and intensity. Compared to the control group, the mouse fibroblasts ratio of the SMG group was higher in the G0/G1 phase but lower in the S phase and G2/M phase...

6p nguaconbaynhay10 20-02-2021 6 2   Download